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Where to go to in chlamydia control? : From infection control towards infectious disease control

van Bergen, Jan E. A. M. (författare)
Amsterdam UMC, AMC, Dept Gen Practice Family Med, NL-1105 AZ Amsterdam, Netherlands.;STI AIDS Netherlands, Amsterdam, Netherlands.;Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.
Hoenderboom, Bernice Maria (författare)
Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.
David, Silke (författare)
Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.
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Deug, Febe (författare)
STI AIDS Netherlands, Amsterdam, Netherlands.
Heijne, Janneke C. M. (författare)
Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.
van Aar, Fleur (författare)
Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.
Hoebe, Christian J. P. A. (författare)
Maastricht Univ, Dept Social Med & Med Microbiol, Fac Hlth Med & Life Sci, Care & Publ Hlth Res Inst, Maastricht, Netherlands.;Publ Hlth Serv South Limburg, Dept Sexual Hlth Infect Dis & Environm Hlth, Heerlen, Netherlands.
Bos, Hanna (författare)
STI AIDS Netherlands, Amsterdam, Netherlands.
Dukers-Muijrers, Nicole H. T. M. (författare)
Maastricht Univ, Dept Hlth Promot, Care & Publ Hlth Res Inst, Maastricht, Netherlands.;Publ Hlth Serv South Limburg, Dept Sexual Hlth Infect Dis & Environm, Heerlen, Netherlands.
Götz, Hannelore M. (författare)
Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.;Rijnmond Publ Hlth Serv, Dept Infect Dis Control, Rotterdam, Netherlands.
Low, Nicola (författare)
Univ Bern, Inst Social & Prevent Med, Bern, Switzerland.
Morre, Servaas Antonie (författare)
Maastricht Univ, Fac Hlth Med & Life Sci, Inst Publ Hlth Genom Genet & Cell Biol, Maastricht, Netherlands.;Natl Inst Publ Hlth & Environm, Dutch Chlamydia Trachomatis Reference Lab, Bilthoven, Netherlands.
Herrmann, Björn, 1955- (författare)
Uppsala universitet,Klinisk mikrobiologi
van der Sande, Marianne A. B. (författare)
Inst Trop Med, Dept Publ Hlth, Antwerp, Belgium.;Univ Utrecht, Julius Ctr, Global Hlth, Utrecht, Netherlands.
de Vries, Henry J. C. (författare)
Publ Hlth Serv Amsterdam, Dept Infect Dis, Amsterdam, Netherlands.;Acad Med Ctr, Dept Dermatol, Amsterdam, Netherlands.
Ward, Helen (författare)
Imperial Coll London, Infect Dis Epidemiol, London, England.
van Benthem, Birgit H. B. (författare)
Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands.
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Amsterdam UMC, AMC, Dept Gen Practice Family Med, NL-1105 AZ Amsterdam, Netherlands;STI AIDS Netherlands, Amsterdam, Netherlands.;Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands. Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands. (creator_code:org_t)
2021-05-27
2021
Engelska.
Ingår i: Sexually Transmitted Infections. - : BMJ Publishing Group Ltd. - 1368-4973 .- 1472-3263. ; 97:7, s. 501-506
  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
Stäng  
  • Objectives: The clinical and public health relevance of widespread case finding by testing for asymptomatic chlamydia infections is under debate. We wanted to explore future directions for chlamydia control and generate insights that might guide for evidence-based strategies. In particular, we wanted to know the extent to which we should pursue testing for asymptomatic infections at both genital and extragenital sites.Methods: We synthesised findings from published literature and from discussions among national and international chlamydia experts during an invitational workshop. We described changing perceptions in chlamydia control to inform the development of recommendations for future avenues for chlamydia control in the Netherlands.Results: Despite implementing a range of interventions to control chlamydia, there is no practice-based evidence that population prevalence can be reduced by screening programmes or widespread opportunistic testing. There is limited evidence about the beneficial effect of testing on pelvic inflammatory disease prevention. The risk of tubal factor infertility resulting from chlamydia infection is low and evidence on the preventable fraction remains uncertain. Overdiagnosis and overtreatment with antibiotics for self-limiting and non-viable infections have contributed to antimicrobial resistance in other pathogens and may affect oral, anal and genital microbiota. These changing insights could affect the outcome of previous cost-effectiveness analysis.Conclusion: The balance between benefits and harms of widespread testing to detect asymptomatic chlamydia infections is changing. The opinion of our expert group deviates from the existing paradigm of 'test and treat' and suggests that future strategies should reduce, rather than expand, the role of widespread testing for asymptomatic chlamydia infections.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

Nyckelord

chlamydia Infections
diagnostic screening programs
health services research
infection control
pelvic inflammatory disease

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