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Sökning: WFRF:(Benediktsdottir Bryndis) > (2020-2024) > Nocturnal gastro-oe...

  • Emilsson, Össur IngiUppsala universitet,Lung- allergi- och sömnforskning,Univ Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland. (författare)

Nocturnal gastro-oesophageal reflux and respiratory symptoms are increased in sleep apnoea : comparison with the general population

  • Artikel/kapitelEngelska2024

Förlag, utgivningsår, omfång ...

  • BMJ Publishing Group Ltd,2024
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-526213
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-526213URI
  • https://doi.org/10.1136/bmjresp-2023-002192DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Aim To assess respiratory symptoms and nocturnal gastro-oesophageal reflux (nGER) among untreated obstructive sleep apnoea (OSA) patients, compared with the general population. Also, if nGER associates differently with respiratory symptoms among OSA patients.Methods 2 study cohorts were included: 822 newly diagnosed subjects with moderate–severe OSA and 738 Icelandic general population study participants. All participants answered the same questionnaires. Those reporting nGER symptoms at least once per week were defined as ‘with nGER’; those without nGER symptoms and without nGER medication were defined as ‘no nGER’; and other participants were defined as having ‘possible nGER’. Propensity score-based weights were used to minimise confounding and selection bias and facilitate causal interpretations.Results The prevalence of nGER among OSA patients was 14.1%, compared with 5.8% in the general population. This increased prevalence in OSA was not explained by differences in age, gender, body mass index, smoking, hypertension and diabetes (adjusted OR (95% CI)=3.79 (2.24 to 6.43)). OSA patients ‘with nGER’ and with ‘possible nGER’ reported more wheezing (44% and 44% vs 25%, respectively) and productive cough (47% and 42% vs 29%, respectively), compared with OSA patients with ‘no nGER’. The same pattern was seen in the general population, although with a generally lower prevalence. The effect of nGER on respiratory symptoms was similar between the two cohorts.Conclusion nGER was more often reported among untreated moderate–severe OSA patients than in the general population. Participants with nGER had more wheezing and productive cough, both among untreated OSA patients and in the general population.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Aspelund, ThorUniv Iceland, Ctr Publ Hlth Sci, Reykjavik, Iceland. (författare)
  • Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning(Swepub:uu)chrisjn (författare)
  • Benediktsdottir, BryndisUniv Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland.;Natl Univ Hosp Iceland, Dept Sleep, Landspitali, Reykjavik, Iceland. (författare)
  • Juliusson, SigurdurNatl Univ Hosp Iceland, Dept Otolaryngol, Landspitali, Reykjavik, Iceland. (författare)
  • Maislin, GregUniv Penn, Perelman Sch Med, Dept Med, Philadelphia, PA USA. (författare)
  • Pack, Allan, IUniv Penn, Perelman Sch Med, Dept Med, Philadelphia, PA USA. (författare)
  • Keenan, Brendan T.Univ Penn, Perelman Sch Med, Dept Med, Philadelphia, PA USA. (författare)
  • Gislason, ThorarinnUniv Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland.;Natl Univ Hosp Iceland, Dept Sleep, Landspitali, Reykjavik, Iceland. (författare)
  • Uppsala universitetLung- allergi- och sömnforskning (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:BMJ Open Respiratory Research: BMJ Publishing Group Ltd11:12052-4439

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