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Search: WFRF:(Botton G. A.) > PharmVar GeneFocus :

  • Sangkuhl, Katrin (author)

PharmVar GeneFocus : CYP2C9

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2021-07-12
  • John Wiley & Sons,2021
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-462626
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462626URI
  • https://doi.org/10.1002/cpt.2333DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature for the polymorphic human CYP2C9 gene. Genetic variation within the CYP2C9 gene locus impacts the metabolism or bioactivation of many clinically important drugs, including nonsteroidal anti-inflammatory drugs, phenytoin, antidiabetic agents, and angiotensin receptor blockers. Variable CYP2C9 activity is of particular importance regarding efficacy and safety of warfarin and siponimod as indicated in their package inserts. This GeneFocus provides a comprehensive overview and summary of CYP2C9 and describes how haplotype information catalogued by PharmVar is utilized by the Pharmacogenomics Knowledgebase and the Clinical Pharmacogenetics Implementation Consortium.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Claudio-Campos, Karla (author)
  • Cavallari, Larisa H (author)
  • Agundez, Jose A G (author)
  • Whirl-Carrillo, Michelle (author)
  • Duconge, Jorge (author)
  • Del Tredici, Andria L (author)
  • Wadelius, MiaUppsala universitet,Institutionen för medicinska vetenskaper,Science for Life Laboratory, SciLifeLab,Klinisk farmakogenomik och osteoporos, Clinical pharmacogenomics and osteoporosis(Swepub:uu)miawadel (author)
  • Rodrigues Botton, Mariana (author)
  • Woodahl, Erica L (author)
  • Scott, Stuart A (author)
  • Klein, Teri E (author)
  • Pratt, Victoria M (author)
  • Daly, Ann K (author)
  • Gaedigk, Andrea (author)
  • Uppsala universitetInstitutionen för medicinska vetenskaper (creator_code:org_t)

Related titles

  • In:Clinical Pharmacology and Therapeutics: John Wiley & Sons110:3, s. 662-6760009-92361532-6535

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