What does the distribution of fitness effects of new mutations reflect?: Insights from plants

Chen, JunZhejiang Univ, Coll Life Sci, Hangzhou 310058, Zhejiang, Peoples R China. (författare)

What does the distribution of fitness effects of new mutations reflect? : Insights from plants

The distribution of fitness effects (DFE) of new mutations plays a central role in molecular evolution. It is therefore crucial to be able to estimate it accurately from genomic data and to understand the factors that shape it. After a rapid overview of available methods to characterize the fitness effects of mutations, we review what is known on the factors affecting them in plants. Available data indicate that life history traits (e.g. mating system and longevity) have a major effect on the DFE. By contrast, the impact of demography within species appears to be more limited. These results remain to be confirmed, and methods to estimate the joint evolution of demography, life history traits, and the DFE need to be developed.

Bataillon, ThomasAarhus Univ, Bioinformat Res Ctr, CF Mollers Alle 8, DK-8000 Aarhus C, Denmark. (författare)
Glemin, SylvainUppsala universitet,Växtekologi och evolution,Univ Rennes, Ctr Natl Rech Sci CNRS, ECOBIO Ecosyst Biodiversite Evolut, Unite Mixte Rech UMR 6553, F-35000 Rennes, France.(Swepub:uu)sylgl118 (författare)
Lascoux, MartinUppsala universitet,Växtekologi och evolution(Swepub:uu)martlasc (författare)
Zhejiang Univ, Coll Life Sci, Hangzhou 310058, Zhejiang, Peoples R China.Aarhus Univ, Bioinformat Res Ctr, CF Mollers Alle 8, DK-8000 Aarhus C, Denmark. (creator_code:org_t)

Av författaren/redakt...: Chen, Jun; Bataillon, Thoma ...; Glemin, Sylvain; Lascoux, Martin

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