NIV-NAVA versus NCPAP immediately after birth in premature infants: A randomized controlled trial

Lee, JuyoungInha Univ, Inha Univ Hosp, Dept Pediat, Coll Med, Incheon, South Korea. (författare)

NIV-NAVA versus NCPAP immediately after birth in premature infants : A randomized controlled trial

Objective: To evaluate whether noninvasive-neurally adjusted ventilatory assist (NIV-NAVA) decrease respiratory efforts compared to nasal continuous positive airway pressure (NCPAP) during the first hours of life.Methods: Twenty infants born between 28+0 and 31+6 weeks were randomized to NIV-NAVA or NCPAP. Positive end-expiratory pressure was constantly kept at 6 cmH(2)O for both groups and the NAVA level was 1.0 cmH(2)O/mu V for NIV-NAVA group. The electrical activity of diaphragm (Edi) were recorded for the first two hours.Results: Peak and minimum Edi decreased similarly in both groups (P = 0.98 and P = 0.59, respectively). Leakages were higher in the NIV-NAVA group than in the NCPAP group (P < 0.001). The neural apnea defined as a flat Edi for >= 5 s were less frequent in NIV-NAVA group than in NCPAP group (P = 0.046).Conclusions: Immediately applied NIV-NAVA in premature infants did not reduce breathing effort, measured as peak Edi. However, NIV-NAVA decreased neural apneic episodes compared to NCPAP.

Parikka, VilhelmiinaTurku Univ Hosp, Dept Pediat & Adolescent Med, Turku, Finland.;Univ Turku, Turku, Finland. (författare)
Oda, ArataNagano Childrens Hosp, Div Neonatol, Nagano, Japan. (författare)
Wallström, Linda,1973-Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning(Swepub:uu)linsi304 (författare)
Lehtonen, LiisaTurku Univ Hosp, Dept Pediat & Adolescent Med, Turku, Finland.;Univ Turku, Turku, Finland. (författare)
Soukka, HannaTurku Univ Hosp, Dept Pediat & Adolescent Med, Turku, Finland.;Univ Turku, Turku, Finland. (författare)
Inha Univ, Inha Univ Hosp, Dept Pediat, Coll Med, Incheon, South Korea.Turku Univ Hosp, Dept Pediat & Adolescent Med, Turku, Finland.;Univ Turku, Turku, Finland. (creator_code:org_t)

Av författaren/redakt...: Lee, Juyoung; Parikka, Vilhelm ...; Oda, Arata; Wallström, Linda ...; Lehtonen, Liisa; Soukka, Hanna

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Lungmedicin och ...

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Pediatrik

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