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  • Willms, A. G.German Armed Forces Cent Hosp Koblenz, Dept Gen Visceral & Thorac Surg, Rubenacher Str 170, D-56072 Koblenz, Germany. (författare)

Factors influencing the fascial closure rate after open abdomen treatment : Results from the European Hernia Society (EuraHS) Registry Surgical technique matters

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • 2020-11-21
  • Springer Nature,2022
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-479459
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-479459URI
  • https://doi.org/10.1007/s10029-020-02336-xDOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Purpose Definitive fascial closure is an essential treatment objective after open abdomen treatment and mitigates morbidity and mortality. There is a paucity of evidence on factors that promote or prevent definitive fascial closure. Methods A multi-center multivariable analysis of data from the Open Abdomen Route of the European Hernia Society included all cases between 1 May 2015 and 31 December 2019. Different treatment elements, i.e. the use of a visceral protective layer, negative-pressure wound therapy and dynamic closure techniques, as well as patient characteristics were included in the multivariable analysis. The study was registered in the International Clinical Trials Registry Platform via the German Registry for Clinical Trials (DRK00021719). Results Data were included from 630 patients from eleven surgical departments in six European countries. Indications for OAT were peritonitis (46%), abdominal compartment syndrome (20.5%), burst abdomen (11.3%), abdominal trauma (9%), and other conditions (13.2%). The overall definitive fascial closure rate was 57.5% in the intention-to-treat analysis and 71% in the per-protocol analysis. The multivariable analysis showed a positive correlation of negative-pressure wound therapy (odds ratio: 2.496, p < 0.001) and dynamic closure techniques (odds ratio: 2.687, p < 0.001) with fascial closure and a negative correlation of intra-abdominal contamination (odds ratio: 0.630, p = 0.029) and the number of surgical procedures before OAT (odds ratio: 0.740, p = 0.005) with DFC. Conclusion The clinical course and prognosis of open abdomen treatment can significantly be improved by the use of treatment elements such as negative-pressure wound therapy and dynamic closure techniques, which are associated with definitive fascial closure.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Schwab, R.German Armed Forces Cent Hosp Koblenz, Dept Gen Visceral & Thorac Surg, Rubenacher Str 170, D-56072 Koblenz, Germany. (författare)
  • von Websky, M. W.Univ Hosp Bonn, Dept Gen Visceral Thorac & Vasc Surg, Sigmund Freud Str 25, D-53127 Bonn, Germany. (författare)
  • Berrevoet, F.Ghent Univ Hosp, Dept Gen & HPB Surg & Liver Transplantat, Corneel Heymanslaan 10, B-9000 Ghent, Belgium. (författare)
  • Tartaglia, D.Cisanello Univ Hosp, Emergency Surg Unit, Via Paradisa 1, I-56124 Pisa, Italy. (författare)
  • Sorelius, K.Univ Copenhagen, Rigshosp, Dept Vasc Surg, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark. (författare)
  • Fortelny, R. H.Wilhelminenspital Stadt Wien, Dept Gen Visceral & Oncol Surg, A-1160 Vienna, Austria.;Sigmund Freud Univ Vienna, Med Fac, A-1020 Vienna, Austria. (författare)
  • Björck, MartinUppsala universitet,Kärlkirurgi(Swepub:uu)mabjo425 (författare)
  • Monchal, T.St Anne Mil Hosp, Dept Gen Surg, 2 Blvd St Anne, F-83000 Toulon, France. (författare)
  • Brennfleck, F.Regensburg Univ Hosp, Dept Surg, Franz Josef Str Allee 11, D-93053 Regensburg, Germany. (författare)
  • Bulian, D.Witten Herdecke Univ, Cologne Merheim Med Ctr, Dept Abdominal Tumor Transplant & Vasc Surg, Ostmerheimer Str 200, D-51109 Cologne, Germany. (författare)
  • Beltzer, C.German Armed Forces Hosp Ulm, Dept Gen Visceral & Thorac Surg, Ulm, Germany. (författare)
  • Germer, C. T.Univ Hosp Wurzburg, Dept Gen Visceral Transplantat Vasc & Pediat Surg, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany. (författare)
  • Lock, J. F.Univ Hosp Wurzburg, Dept Gen Visceral Transplantat Vasc & Pediat Surg, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany. (författare)
  • German Armed Forces Cent Hosp Koblenz, Dept Gen Visceral & Thorac Surg, Rubenacher Str 170, D-56072 Koblenz, Germany.Univ Hosp Bonn, Dept Gen Visceral Thorac & Vasc Surg, Sigmund Freud Str 25, D-53127 Bonn, Germany. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Hernia: Springer Nature26:1, s. 61-731265-49061248-9204

Internetlänk

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  • Hernia (Sök värdpublikationen i LIBRIS)

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