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Performance of crea...
Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil, and Africa
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- Delanaye, Pierre (författare)
- Department of Nephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hôpital Universitaire Carémeau, Nîmes, France
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- Vidal-Petiot, Emmanuelle (författare)
- Assistance Publique-Hôpitaux de Paris, Bichat Hospital, and Université de Paris, INSERM U1149, Paris, France.,Université Paris Cité
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- Björk, Jonas (författare)
- Lund University,Lunds universitet,Centrum för ekonomisk demografi,Ekonomihögskolan,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Kirurgi och folkhälsa,Forskargrupper vid Lunds universitet,EPI@LUND,Centre for Economic Demography,Lund University School of Economics and Management, LUSEM,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Surgery and public health,Lund University Research Groups,Skåne University Hospital
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- Ebert, Natalie (författare)
- Charité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.,Charité - University Medicine Berlin
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- Eriksen, Björn O (författare)
- Section of Nephrology, University Hospital of North Norway and Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway.
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- Dubourg, Laurence (författare)
- Néphrologie, Dialyse, Hypertension et Exploration Fonctionnelle Rénale, Hôpital Edouard Herriot, Hospices Civils de Lyon, France.
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- Grubb, Anders (författare)
- Lund University,Lunds universitet,Cystatin C, njursjukdom, amyloidos och antibiotika,Forskargrupper vid Lunds universitet,Cystatin C, renal disease, amyloidosis and antibiotics,Lund University Research Groups,Skåne University Hospital
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- Hansson, Magnus (författare)
- Karolinska Institutet,Karolinska University Hospital
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- Littmann, Karin (författare)
- Karolinska Institute,Karolinska Institutet
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- Mariat, Christophe (författare)
- Service de Néphrologie, Dialyse et Transplantation Rénale, Hôpital Nord, CHU de Saint-Etienne, France.
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- Melsom, Toralf (författare)
- rch Group, UiT The Arctic University of Norway, Tromsö, Norway.,Section of Nephrology, University Hospital of North Norway and Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway
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- Schaeffner, Elke (författare)
- Charité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.,Charité - University Medicine Berlin
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- Sundin, Per-Ola, 1971- (författare)
- Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Geriatrics,School of Medical Sciences, Örebro University, Örebro, Sweden.
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- Bökenkamp, Arend (författare)
- Department of Paediatric Nephrology, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
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- Berg, Ulla B (författare)
- Karolinska Institutet,Karolinska University Hospital
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- Åsling-Monemi, Kajsa (författare)
- Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
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- Åkesson, Anna (författare)
- Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Skåne University Hospital
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- Larsson, Anders (författare)
- Uppsala University,Uppsala universitet,Klinisk kemi,Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden
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- Cavalier, Etienne (författare)
- Department of Clinical Chemistry, University of Liège (ULiege), CHU Sart Tilman, Liège, Belgium,University of Liège Hospital
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- Dalton, R Neil (författare)
- The Wellchild Laboratory, Evelina London Children's Hospital, London, United Kingdom.,Evelina London Children's Healthcare
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- Courbebaisse, Marie (författare)
- Physiology Department, Georges Pompidou European Hospital, Assistance Publique Hôpitaux de Paris, Paris University, INSERM, ParisFrance.,Physiology Department, Georges Pompidou European Hospital, Assistance Publique Hôpitaux de Paris, Paris University, INSERM, Paris, France
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- Couzi, Lionel (författare)
- CHU de Bordeaux, Nephrologie - Transplantation - Dialyse, Université de Bordeaux, CNRS-UMR Immuno ConcEpT, France.,Centre Hospitalier Universitaire de Bordeaux
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- Gaillard, Francois (författare)
- Service de transplantation et immunologie clinique, Hopital Edouard Herriot, Hospices civils de Lyon, LyonFrance.,Service de transplantation et immunologie clinique, Hopital Edouard Herriot, Hospices civils de Lyon, Lyon, France
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- Garrouste, Cyril (författare)
- Department of Nephrology, Clermont-Ferrand University Hospital, Clermont-Ferrand, France.
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- Jacquemont, Lola (författare)
- Renal Transplantation Department, CHU Nantes, Nantes University, Nantes, France.,Nantes University Hospital
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- Kamar, Nassim (författare)
- Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, INSERM U1043, IFR -BMT, University Paul Sabatier, Toulouse, France.,Rangueil Hospital
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- Legendre, Christophe (författare)
- Hôpital Necker, Assistance Publique Hôpitaux de Paris, Paris University, France.,Necker-Enfants Malades Hospital
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- Rostaing, Lionel (författare)
- Service de Néphrologie, Hémodialyse, Aphérèses et Transplantation Rénale, Hôpital Michallon, CHU Grenoble-Alpes, France.,Grenoble University Hospital
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- Stehlé, Thomas (författare)
- Université Paris Est Créteil, INSERM, Institut Mondor de Recherche Biomédicale (IMRB), Créteil, France; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Henri Mondor, Service de Néphrologie et Transplantation, Fédération Hospitalo-Universitaire « Innovative therapy for immune disorders », Créteil, France
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- Haymann, Jean-Philippe (författare)
- Physiology Department, Assistance Publique- Hôpitaux de Paris, Hôpital Tenon, Paris, France.
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- da Silva Selistre, Luciano (författare)
- Curso de pós-graduação em Ciências da Saúde, Universidade de Caxias do Sul, Hospital Geral de Caxias do Sul, Caxias do Sul, Brazil.,University of Caxias do Sul
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- Strogoff-de-Matos, Jorge P (författare)
- Nephrology Division, Department of Medicine, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.,Fluminense Federal University
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- Bukabau, Justine B (författare)
- Renal Unit, Department of Internal Medicine, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
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- Sumaili, Ernest K (författare)
- Département de Biochimie, UFR Sciences Pharmaceutiques et Biologiques, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.,Renal Unit, Department of Internal Medicine, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo
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- Yayo, Eric (författare)
- Département de Biochimie, UFR Sciences Pharmaceutiques et Biologiques, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
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- Monnet, Dagui (författare)
- Département de Biochimie, UFR Sciences Pharmaceutiques et Biologiques, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
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- Nyman, Ulf (författare)
- Lund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Radiology Diagnostics, Malmö,Lund University Research Groups
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- Pottel, Hans (författare)
- Department of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.,Catholic University of Leuven
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- Flamant, Martin (författare)
- Assistance Publique-Hôpitaux de Paris, Bichat Hospital, and Université de Paris, Cordeliers Research Center, Paris, France.,Centre de Recherche des Cordeliers
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Department of Nephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hôpital Universitaire Carémeau, Nîmes, France Assistance Publique-Hôpitaux de Paris, Bichat Hospital, and Université de Paris, INSERM U1149, Paris, France (creator_code:org_t)
- 2022-08-24
- 2022
- Engelska.
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Ingår i: Nephrology, Dialysis and Transplantation. - : Oxford University Press. - 0931-0509 .- 1460-2385. ; 38:1, s. 106-118
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- BACKGROUND: A new Chronic Kidney Disease Epidemiology equation without race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared to the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts.METHODS: Standardized creatinine and measured glomerular filtration rate (GFR) from the European EKFC cohorts (n = 13 856 including 6031 individuals in the external validation cohort), from France, (n = 4429, including 964 Black Europeans), from Brazil (n = 100), and from Africa (n = 508) were used to test the performances of the equations. A matched analysis between White Europeans and Black Africans or Black Europeans was performed.RESULTS: In White Europeans (n = 9496), both the EKFC and LMREV equations outperformed CKD-EPIAS (bias of -0.6 and -3.2, respectively versus 5.0 mL/min/1.73m², and accuracy within 30% of 86.9 and 87.4, respectively versus 80.9%). In Black Europeans and Black Africans, the best performance was observed with the EKFC equation using a specific Q-value ( = concentration of serum creatinine in healthy males and females). These results were confirmed in matched analyses, which showed that serum creatinine concentrations were different in White Europeans, Black Europeans, and Black Africans for the same measured GFR, age, sex and body mass index. Creatinine differences were more relevant in males.CONCLUSION: In a European and African cohort, the performances of CKD-EPIAS remain suboptimal. The EKFC equation, using usual or dedicated, population-specific Q-values presents the best performance in the whole age range in the European and African populations included in this study.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- creatinine
- glomerular filtration rate
- race
- creatinine
- glomerular filtration rate
- race
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Delanaye, Pierre
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Vidal-Petiot, Em ...
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Björk, Jonas
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Ebert, Natalie
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Eriksen, Björn O
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Dubourg, Laurenc ...
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visa fler...
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Grubb, Anders
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Hansson, Magnus
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Littmann, Karin
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Mariat, Christop ...
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Melsom, Toralf
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Schaeffner, Elke
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Sundin, Per-Ola, ...
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Bökenkamp, Arend
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Berg, Ulla B
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Åsling-Monemi, K ...
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Åkesson, Anna
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Larsson, Anders
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Cavalier, Etienn ...
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Dalton, R Neil
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Courbebaisse, Ma ...
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Couzi, Lionel
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Gaillard, Franco ...
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Garrouste, Cyril
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Jacquemont, Lola
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Kamar, Nassim
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Legendre, Christ ...
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Rostaing, Lionel
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Stehlé, Thomas
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Haymann, Jean-Ph ...
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da Silva Selistr ...
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Strogoff-de-Mato ...
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Bukabau, Justine ...
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Sumaili, Ernest ...
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Yayo, Eric
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Monnet, Dagui
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Nyman, Ulf
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Pottel, Hans
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Flamant, Martin
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Urologi och njur ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Arbetsmedicin oc ...
- Artiklar i publikationen
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Nephrology, Dial ...
- Av lärosätet
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Uppsala universitet
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Örebro universitet
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Karolinska Institutet
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Lunds universitet