Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity

Hemming, Joanna M.Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England. (författare)

Exposure to the secondary pollutant ozone in ambient air is associated with adverse health effects when inhaled. In this work we use surface pressure measurements, combined with X-ray and neutron reflection, to observe changes in a layer of lung surfactant at the air water interface when exposed to gas phase ozone. The results demonstrate that the layer reacts with ozone changing its physical characteristics. A slight loss of material, a significant thinning of the layer and increased hydration of the surfactant material is observed. The results support the hypothesis that unsaturated lipids present in lung surfactant are still susceptible to rapid reaction with ozone and the reaction changes the properties of the interfacial layer.

Szyroka, JustynaUniv London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England. (författare)
Shokano, GraciaUniv London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England. (författare)
Arnold, ThomasEuropean Spallat Source, ESS Campus, Lund, Sweden.;CISIS Neutron & Muon Source, Sci & Technol Fac Council, Rutherford Appleton Lab, Harwell OX11 0QX, Berks, England.;Univ Bath, Dept Chem, Claverton Down, Bath BA2 7AY, Avon, England. (författare)
Skoda, Maximilian W. A.CISIS Neutron & Muon Source, Sci & Technol Fac Council, Rutherford Appleton Lab, Harwell OX11 0QX, Berks, England. (författare)
Rennie, Adrian R.,1957-Uppsala universitet,Institutionen för fysik och astronomi(Swepub:uu)adren227 (författare)
Thompson, Katherine C.Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England. (författare)
Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England.European Spallat Source, ESS Campus, Lund, Sweden.;CISIS Neutron & Muon Source, Sci & Technol Fac Council, Rutherford Appleton Lab, Harwell OX11 0QX, Berks, England.;Univ Bath, Dept Chem, Claverton Down, Bath BA2 7AY, Avon, England. (creator_code:org_t)

Ingår i:Environmental Science: Royal Society of Chemistry2:4, s. 753-7602634-3606

Av författaren/redakt...: Hemming, Joanna ...; Szyroka, Justyna; Shokano, Gracia; Arnold, Thomas; Skoda, Maximilia ...; Rennie, Adrian R ...; visa fler...; Thompson, Kather ...; visa färre...

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