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Mandibular resection in patients with head and neck cancer : acute and long-term complications after reconstruction

Sjöström, Mats (författare)
Umeå universitet,Institutionen för odontologi,Department of Odontology, Oral and Maxillofacial Surgery, Umeå University Hospital, Umeå, Sweden
Danielsson, Daniel (författare)
Karolinska Inst, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.;Karolinska Univ Hosp, Craniofacial Dis, Patient Area, Stockholm, Sweden,Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden;Patient Area, Craniofacial Diseases, Karolinska University Hospital, Stockholm, Sweden
Munck-Wikland, Eva (författare)
Karolinska Inst, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.;Karolinska Univ Hosp, Patient Area Head & Neck Lung & Skin Canc, Stockholm, Sweden,Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden;Patient Area Head and Neck-, Lung-, and Skin-Cancer, Karolinska University Hospital, Stockholm, Sweden
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Nyberg, Jan (författare)
Örebro Univ Hosp, Ctr Head & Neck Oncol, Dept Oral & Maxillofacial Surg, Örebro, Sweden,Department of Oral and Maxillofacial Surgery, Centre for Head and Neck Oncology, Örebro University Hospital, Örebro, Sweden
Sandström, Karl, 1973- (författare)
Uppsala universitet,Öron-, näs- och halssjukdomar,Otolaryngology and Head and Neck surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Thor, Andreas (författare)
Uppsala universitet,Odontologi & Maxillofacial kirurgi,Oral and Maxillofacial Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Johansson, Hemming (författare)
Karolinska Institutet,Department of Oncology and Pathology, Karolinska Institute and University Hospital, Stockholm, Sweden
Ceghafi, Payam (författare)
Örebro Univ Hosp, Ctr Head & Neck Oncol, Dept Oral & Maxillofacial Surg, Örebro, Sweden,Department of Oral and Maxillofacial Surgery, Centre for Head and Neck Oncology, Örebro University Hospital, Örebro, Sweden
Udd, Sebastian Dybeck (författare)
Karolinska Univ Hosp, Craniofacial Dis, Patient Area, Stockholm, Sweden,Patient Area, Craniofacial Diseases, Karolinska University Hospital, Stockholm, Sweden
Emanuelsson, Jonas (författare)
Umeå Univ Hosp, Dept Odontol Oral & Maxillofacial Surg, Umeå, Sweden,Department of Odontology, Oral and Maxillofacial Surgery, Umeå University Hospital, Umeå, Sweden
Pettersson, Linda Forsberg (författare)
Umeå Univ Hosp, Dept Odontol Oral & Maxillofacial Surg, Umeå, Sweden,Department of Odontology, Oral and Maxillofacial Surgery, Umeå University Hospital, Umeå, Sweden
Halle, Martin (författare)
Karolinska Institutet,Department of Molecular Medicine and Surgery, Karolinska Institute and Reconstructive Plastic Surgery, Karolinska University Hospital, Stockholm, Sweden
Laurell, Göran (författare)
Uppsala universitet,Öron-, näs- och halssjukdomar,Otolaryngology and Head and Neck surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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 (creator_code:org_t)
2022-01-13
2022
Engelska.
Ingår i: Acta Oto-Laryngologica. - : Taylor & Francis Group. - 0001-6489 .- 1651-2251. ; 142:1, s. 78-83
Relaterad länk:
https://doi.org/10.1...
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https://www.tandfonl...
https://umu.diva-por... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
http://kipublication...
https://urn.kb.se/re...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background The treatment of head and neck cancer is an intensive multimodal treatment that has a great impact on the individual patient.Aims/Objectives This study aimed to evaluate acute and long-term complications associated with mandibular resections and reconstructions.Material and Methods We retrospectively retrieved data on complications and recurrences among patients that underwent mandibular resections and reconstructions for treating oral cavity cancer (n = 190 patients) and osteoradionecrosis (ORN, n = 72). Reconstructions included composite grafts (n = 177), soft tissue flaps (n = 61), or primary closure without any graft (n = 24).Results Forty-two patients that underwent reconstructions with composite grafts displayed serious complications (Clavien-Dindo >= IIIa). The complication rates were similar between patients treated for oral cavity cancer and patients treated for ORN. Patients that underwent a primary closure without any graft, had a significantly lower risk of complications compared to patients that underwent the other treatments. After hospitalization, 181 patients (69%) had at least one complication.Conclusions A majority of patients undergoing resection and reconstruction due to oral cancer/ORN suffered from postoperative complications regardless of indication, comorbidity status or reconstruction technique. The risk of Clavien-Dindo grade IIIa-V events was significantly lower for patients treated with primary closure without grafts Significance The results from this study clarifies the importance of in-depth analyse prior to decision of treatment for patients with head and neck cancer.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

Head and neck cancer
mandible
resection
reconstruction
affecting factors
complications

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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