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Phage-tail-like bac...
Phage-tail-like bacteriocins as a biomedical platform to counter anti-microbial resistant pathogens
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- Bhattacharjee, Rahul (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Nandi, Aditya (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Sinha, Adrija (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Kumar, Hrithik (författare)
- Indian Inst Sci Educ & Res IISER, Sch Biol, Thiruvananthapuram 695551, Kerala, India.
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- Mitra, Disha (författare)
- Univ Calcutta, 92,APC Rd, Kolkata 700009, India.
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- Mojumdar, Abhik (författare)
- Korea Basic Sci Inst KBSI, Ctr Res Equipment, Ochang Ctr, Cheongju 28119, Chungcheongbuk, South Korea.;Univ Sci & Technol UST, Dept Bioanalyt Sci, Daejeon 34113, South Korea.
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- Patel, Paritosh (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Jha, Ealisha (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Mishra, Suman (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Rout, Prabhat Kumar (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Panda, Pritam Kumar, PhD Student, 1991- (författare)
- Uppsala universitet,Materialteori
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- Suar, Mrutyunjay (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India.
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- Verma, Suresh K. (författare)
- Uppsala universitet,Materialteori,KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India
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KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Orissa, India Indian Inst Sci Educ & Res IISER, Sch Biol, Thiruvananthapuram 695551, Kerala, India. (creator_code:org_t)
- Elsevier, 2022
- 2022
- Engelska.
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Ingår i: Biomedicine and Pharmacotherapy. - : Elsevier. - 0753-3322 .- 1950-6007. ; 155
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Phage Tail Like bacteriocins (PTLBs) has been an area of interest in the last couple of years owing to their varied application against multi-drug resistant (MDR), anti-microbial resistant (AMR) pathogens and their evolutionary link with the dsDNA virus and bacteriophages. PTLBs are defective phages derived from Myoviridae and Sipho-viridae phages, PTLBs are distinguished into R-type (Rigid type) characterized by a non-flexible contractile nanotube resembling Myoviridae phage contractile tails, and F-type (Flexible type) with a flexible non-contractile rod-like structure similar to Siphoviridae phages. In this review, we have discussed the structural association, mechanism, and characterization of PTLBs. Moreover, we have elucidated the symbiotic biological function and application of PTLBs against MDR and XDR pathogens and highlighted the evolutionary role of PTLBs. The difficulties that must be overcome to implement PTLBs clinically are also discussed. It is imperative that these issues be addressed by academics in future studies before being implemented in clinical settings. This article is novel in its way as it will not only provide us with a gateway that acts as a novel strategy for scholars to mitigate and control the uprising issue of AMR pathogens but also promote the development of clinical studies for PTLBs.
Ämnesord
- NATURVETENSKAP -- Biologi -- Mikrobiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Microbiology (hsv//eng)
Nyckelord
- Bacteriocins
- Phage
- Multi-drug resistant pathogen
- Anti-microbial activity
- Phage tail-like bacteriocin
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- ref (ämneskategori)
- for (ämneskategori)
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Bhattacharjee, R ...
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Nandi, Aditya
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Sinha, Adrija
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Kumar, Hrithik
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Mitra, Disha
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Mojumdar, Abhik
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visa fler...
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Patel, Paritosh
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Jha, Ealisha
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Mishra, Suman
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Rout, Prabhat Ku ...
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Panda, Pritam Ku ...
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Suar, Mrutyunjay
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Verma, Suresh K.
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visa färre...
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
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och Mikrobiologi
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Biomedicine and ...
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Uppsala universitet