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Novel Benchmark Val...
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Abbassi, FaribaUniv Hosp Zurich, Dept Surg & Transplantat, Zurich, Switzerland.
(author)
Novel Benchmark Values for Redo Liver Transplantation Does the Outcome Justify the Effort?
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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Lippincott Williams & Wilkins,2022
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-487670
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-487670URI
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https://doi.org/10.1097/SLA.0000000000005634DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:150935981URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Objective: To define benchmark cutoffs for redo liver transplantation (redo-LT). Background: In the era of organ shortage, redo-LT is frequently discussed in terms of expected poor outcome and wasteful resources. However, there is a lack of benchmark data to reliably evaluate outcomes after redo-LT. Methods: We collected data on redo-LT between January 2010 and December 2018 from 22 high-volume transplant centers. Benchmark cases were defined as recipients with model of end stage liver disease (MELD) score <= 25, absence of portal vein thrombosis, no mechanical ventilation at the time of surgery, receiving a graft from a donor after brain death. Also, high-urgent priority and early redo-LT including those for primary nonfunction (PNF) or hepatic artery thrombosis were excluded. Benchmark cutoffs were derived from the 75th percentile of the medians of all benchmark centers. Results: Of 1110 redo-LT, 373 (34%) cases qualified as benchmark cases. Among these cases, the rate of postoperative complications until discharge was 76%, and increased up to 87% at 1-year, respectively. One-year overall survival rate was excellent with 90%. Benchmark cutoffs included Comprehensive Complication Index CCI (R) at 1-year of <= 72, and in-hospital and 1-year mortality rates of <= 13% and <= 15%, respectively. In contrast, patients who received a redo-LT for PNF showed worse outcomes with some values dramatically outside the redoLT benchmarks. Conclusion: This study shows that redo-LT achieves good outcome when looking at benchmark scenarios. However, this figure changes in high-risk redo-LT, as for example in PNF. This analysis objectifies for the first-time results and efforts for redo-LT and can serve as a basis for discussion about the use of scarce resources.
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Gero, DanielUniv Hosp Zurich, Dept Surg & Transplantat, Zurich, Switzerland.
(author)
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Muller, XavierCroix Rousse Hosp, Dept Gen Abdominal & Transplant Surg, Lyon, France.
(author)
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Bueno, AlbaKings Coll Hosp London, Inst Liver Studies, London, England.
(author)
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Figiel, WojciechMed Univ Warsaw, Dept Gen Transplant & Liver Surg, Warsaw, Poland.
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Robin, FabienUniv Hosp Rennes, Dept HPB Surg & Transplantat, Rennes, France.
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Laroche, SophieHop Paul Brousse, Hepatobiliary Ctr, Dept Surg & Transplantat, Villejuif, France.
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Picard, BenjaminHop Beaujon, APHP Nord, DMU PARABOL, Dept Anesthesiol Crit Care & Perioperat Med, Clichy, Nord, France.
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Shankar, SadhanaLeeds Teaching Hosp trust, Dept Abdominal Transplant & Hepatobiliary Surg, Leeds, W Yorkshire, England.
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Ivanics, TommyUppsala universitet,Gastrointestinalkirurgi,Univ Toronto, Univ Hlth Network, Multiorgan Transplant Program, Toronto, ON, Canada.;Henry Ford Hosp, Dept Surg, Detroit, MI USA.(Swepub:uu)tomiv601
(author)
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van Reeven, MarjoleinUniv Med Ctr Rotterdam, Erasmus MC Transplant Inst, Dept Surg, Div HPB & Transplant Surg, Rotterdam, Netherlands.
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van Leeuwen, Otto B.Univ Groningen, Univ Med Ctr Groningen, Div HPB Surg & Liver Transplantat, Groningen, Netherlands.
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Braun, Hillary J.Univ Calif San Francisco, Div Transplant Surg, San Francisco, CA USA.
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Monbaliu, DiethardUniv Hosp Leuven, Dept Abdominal Transplant Surg & Transplant Coord, Leuven, Belgium.
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Breton, AntoineCroix Rousse Hosp, Dept Gen Abdominal & Transplant Surg, Lyon, France.
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Vachharajani, NeetaWashington Univ, St Louis Sch Med, Div Abdominal Transplantat, Dept Surg, St Louis, MO USA.
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Bonaccorsi Riani, ElianoUniv Hosp St Luc, Dept Abdominal & Transplant Surg, Brussels, Belgium.
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Nowak, GregKarolinska Institutet
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McMillan, Robert R.Houston Methodist Hosp, Weill Cornell Med Ctr, Houston, TX USA.
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Abu-Gazala, SamirHosp Univ Penn, Penn Transplant Inst, Dept Surg, Philadelphia, PA USA.
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Nair, AmitUniv Rochester, Div Transplantat & Hepatobiliary Surg, Rochester, MN USA.
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Bruballa, RocioHosp Italiano Buenos Aires, HPB & Liver Transplant Unit, Buenos Aires, Argentina.
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Paterno, FlavioUniv Hosp, Rutgers New Jersey Med Sch, Div Liver Transplant, Newark, NJ USA.
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Weppler Sears, DeborahCleveland Clin Florida, Dept Abdominal & Transplant Surg, Weston, FL USA.
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Pinna, Antonio D.Cleveland Clin Florida, Dept Abdominal & Transplant Surg, Weston, FL USA.
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Guarrera, James V.Univ Hosp, Rutgers New Jersey Med Sch, Div Liver Transplant, Newark, NJ USA.
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de Santibanes, EduardoHosp Italiano Buenos Aires, HPB & Liver Transplant Unit, Buenos Aires, Argentina.
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de Santibanes, MartinHosp Italiano Buenos Aires, HPB & Liver Transplant Unit, Buenos Aires, Argentina.
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Hernandez-Alejandro, RobertoUniv Rochester, Div Transplantat & Hepatobiliary Surg, Rochester, MN USA.
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Olthoff, KimHosp Univ Penn, Penn Transplant Inst, Dept Surg, Philadelphia, PA USA.
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Ghobrial, R. MarkHouston Methodist Hosp, Weill Cornell Med Ctr, Houston, TX USA.
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Ericzon, Bo-GoranKarolinska Institutet
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Ciccarelli, OlgaUniv Hosp St Luc, Dept Abdominal & Transplant Surg, Brussels, Belgium.
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Chapman, William C.Washington Univ, St Louis Sch Med, Div Abdominal Transplantat, Dept Surg, St Louis, MO USA.
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Mabrut, Jean-YvesCroix Rousse Hosp, Dept Gen Abdominal & Transplant Surg, Lyon, France.
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Pirenne, JacquesUniv Hosp Leuven, Dept Abdominal Transplant Surg & Transplant Coord, Leuven, Belgium.
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Mullhaupt, BeatUniv Hosp Zurich, Dept Gastroenterol & Hepatol, Zurich, Switzerland.
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Ascher, Nancy L.Univ Calif San Francisco, Div Transplant Surg, San Francisco, CA USA.
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Porte, Robert J.Univ Groningen, Univ Med Ctr Groningen, Div HPB Surg & Liver Transplantat, Groningen, Netherlands.
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de Meijer, Vincent E.Univ Groningen, Univ Med Ctr Groningen, Div HPB Surg & Liver Transplantat, Groningen, Netherlands.
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Polak, Wojciech G.Univ Med Ctr Rotterdam, Erasmus MC Transplant Inst, Dept Surg, Div HPB & Transplant Surg, Rotterdam, Netherlands.
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Sapisochin, GonzaloUniv Toronto, Univ Hlth Network, Multiorgan Transplant Program, Toronto, ON, Canada.
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Attia, MagdyLeeds Teaching Hosp trust, Dept Abdominal Transplant & Hepatobiliary Surg, Leeds, W Yorkshire, England.
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Soubrane, OlivierHop Beaujon, APHP Nord, DMU DIGEST, Dept HPB Surg & Liver Transplantat, Clichy, France.
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Weiss, EmmanuelHop Beaujon, APHP Nord, DMU PARABOL, Dept Anesthesiol Crit Care & Perioperat Med, Clichy, Nord, France.
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Adam, Rene A.Hop Paul Brousse, Hepatobiliary Ctr, Dept Surg & Transplantat, Villejuif, France.
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Cherqui, DanielHop Paul Brousse, Hepatobiliary Ctr, Dept Surg & Transplantat, Villejuif, France.
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Boudjema, KarimUniv Hosp Rennes, Dept HPB Surg & Transplantat, Rennes, France.
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Zieniewicz, KrzysztofMed Univ Warsaw, Dept Gen Transplant & Liver Surg, Warsaw, Poland.
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Jassem, WayelKings Coll Hosp London, Inst Liver Studies, London, England.
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Dutkowski, PhilippUniv Hosp Zurich, Dept Surg & Transplantat, Zurich, Switzerland.
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Clavien, Pierre-AlainUniv Hosp Zurich, Dept Surg & Transplantat, Zurich, Switzerland.
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Univ Hosp Zurich, Dept Surg & Transplantat, Zurich, Switzerland.Croix Rousse Hosp, Dept Gen Abdominal & Transplant Surg, Lyon, France.
(creator_code:org_t)
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In:Annals of Surgery: Lippincott Williams & Wilkins276:5, s. 860-8670003-49321528-1140
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Abbassi, Fariba
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Gero, Daniel
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Muller, Xavier
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Bueno, Alba
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Figiel, Wojciech
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Robin, Fabien
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Laroche, Sophie
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Picard, Benjamin
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Shankar, Sadhana
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Ivanics, Tommy
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van Reeven, Marj ...
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van Leeuwen, Ott ...
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Braun, Hillary J ...
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Monbaliu, Dietha ...
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Breton, Antoine
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Vachharajani, Ne ...
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Bonaccorsi Riani ...
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Nowak, Greg
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McMillan, Robert ...
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Abu-Gazala, Sami ...
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Nair, Amit
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Bruballa, Rocio
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Paterno, Flavio
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Weppler Sears, D ...
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Pinna, Antonio D ...
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Guarrera, James ...
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de Santibanes, E ...
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de Santibanes, M ...
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Hernandez-Alejan ...
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Olthoff, Kim
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Ghobrial, R. Mar ...
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Ericzon, Bo-Gora ...
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Ciccarelli, Olga
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Chapman, William ...
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Mabrut, Jean-Yve ...
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Pirenne, Jacques
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Mullhaupt, Beat
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Ascher, Nancy L.
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Porte, Robert J.
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de Meijer, Vince ...
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Polak, Wojciech ...
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Sapisochin, Gonz ...
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Attia, Magdy
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Soubrane, Olivie ...
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Weiss, Emmanuel
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Adam, Rene A.
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Cherqui, Daniel
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Boudjema, Karim
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Zieniewicz, Krzy ...
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Jassem, Wayel
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Dutkowski, Phili ...
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