Visualization of the Fetal Lip and Palate: Is Brain-Targeted MRI Reliable?

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Canto Moreira, NunoUppsala universitet,Enheten för radiologi,Neuroradiology Section C, Campos Costa, Porto, Portugal;Department of Radiology, Uppsala University, Uppsala, Sweden. (author)

Visualization of the Fetal Lip and Palate: Is Brain-Targeted MRI Reliable?

Article/chapterEnglish2013

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2013-09-01
SAGE Publications,2013
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LIBRIS-ID:oai:DiVA.org:uu-489734
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489734URI
https://doi.org/10.1597/12-079DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-194154URI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

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To evaluate the ability of brain-targeted magnetic resonance imaging (MRI) to assess the anatomy of the fetal upper lip and palate. Design Two independent readers made a blind retrospective review of 60 brain-targeted MRIs of fetuses from 20 to 38 gestational weeks (GW). Fifty-five MRIs were normal and five had orofacial anomalies, including one isolated cleft lip and four cleft lip and palate. Both normal and cleft MRIs had postnatal confirmation. The upper lip, primary palate, secondary palate, and nasal septum were scored into four levels, from evidently normal to evidently abnormal. In case of a suspected pathology, the readers attempted a diagnosis. Setting Collaboration between a university hospital and a large private practice MRI center. Results Interobserver agreement (weighted kappa) was 0.79 for the upper lip, 0.70 for the primary palate, 0.86 for the secondary palate, and 0.90 for the nasal septum. The scoring levels of the readers did not change significantly across gestational age. Normality was correctly scored in 96% to 100% of the normal lips and primary palates and in 93% to 97% of the normal secondary palates depending on the reader. A deviated septum was only scored in two fetuses with unilateral cleft palates. The readers identified all pathological cases. Conclusion Brain-targeted fetal MRI in experienced hands seems to be highly accurate for the evaluation of the lip and palate in fetuses above 20 GW, regardless of gestational age. The assessment of the secondary palate may be slightly more limited than the lip or primary palate.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
Radiology
Radiologi

Added entries (persons, corporate bodies, meetings, titles ...)

Ribeiro, ValentinaDepartment of Neuroradiology, H. G. S. Antonio, Porto, Portugal. (author)
Teixeira, JoãoDepartment of Radiology, Uppsala University, Uppsala, Sweden. (author)
Raininko, RailiUppsala universitet,Enheten för radiologi,Department of Radiology, Uppsala University, Uppsala, Sweden.(Swepub:uu)railrain (author)
Wikstrom, JohanUppsala universitet,Enheten för radiologi,Department of Radiology, Uppsala University, Uppsala, Sweden.(Swepub:uu)jwi06759 (author)
Uppsala universitetEnheten för radiologi (creator_code:org_t)

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In:The Cleft Palate-Craniofacial Journal: SAGE Publications50:5, s. 513-5191055-66561545-1569

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