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  • Wang, ShujiangUppsala universitet,Institutionen för kemi - Ångström (author)

Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • 2022
  • Royal Society of Chemistry (RSC),2022
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-491065
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-491065URI
  • https://doi.org/10.1039/d2bm01154aDOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

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  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • Hyaluronic acid (HA), one of the main components of the extracellular matrix (ECM), is extensively used in the design of hydrogels and nanoparticles for different biomedical applications due to its critical role in vivo, degradability by endogenous enzymes, and absence of immunogenicity. HA-based hydrogels and nanoparticles have been developed by utilizing different crosslinking chemistries. The development of such crosslinking chemistries indicates that even subtle differences in the structure of reactive groups or the procedure of crosslinking may have a profound impact on the intended mechanical, physical and biological outcomes. There are widespread examples of modified HA polymers that can form either covalently or physically crosslinked biomaterials. More recently, studies have been focused on dynamic covalent crosslinked HA-based biomaterials since these types of crosslinking allow the preparation of dynamic structures with the ability to form in situ, be injectable, and have self-healing properties. In this review, HA-based hydrogels and nanomaterials that are crosslinked by dynamic-covalent coupling (DCC) chemistry have been critically assessed.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Tavakoli, ShimaUppsala universitet,Institutionen för kemi - Ångström(Swepub:uu)shita882 (author)
  • Parvathaneni, Rohith PavanUppsala universitet,Institutionen för kemi - Ångström(Swepub:uu)rohpa649 (author)
  • Nawale, Ganesh N.Uppsala universitet,Institutionen för kemi - Ångström(Swepub:uu)ganna194 (author)
  • Oommen, Oommen P.Tampere Univ, Fac Med & Hlth Technol, Bioengn & Nanomed Grp, Tampere 33720, Finland. (author)
  • Hilborn, Jöns,1956-Uppsala universitet,Institutionen för kemi - Ångström(Swepub:uu)johil255 (author)
  • Varghese, Oommen P.,1977-Uppsala universitet,Institutionen för kemi - Ångström(Swepub:uu)oopva021 (author)
  • Uppsala universitetInstitutionen för kemi - Ångström (creator_code:org_t)

Related titles

  • In:Biomaterials Science: Royal Society of Chemistry (RSC)10:22, s. 6399-64122047-48302047-4849

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