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Association of resp...
Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study
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Ratanachina, Jate (author)
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Amaral, Andre F. S. (author)
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De Matteis, Sara (author)
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Lawin, Herve (author)
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Mortimer, Kevin (author)
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Obaseki, Daniel O. (author)
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Harrabi, Imed (author)
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Denguezli, Meriam (author)
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Wouters, Emiel F. M. (author)
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- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
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Nielsen, Rune (author)
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Gulsvik, Amund (author)
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Hacene Cherkaski, Hamid (author)
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Mejza, Filip (author)
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Padukudru Anand, Mahesh (author)
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Elsony, Asma (author)
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Ahmed, Rana (author)
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Tan, Wan (author)
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Li Cher, Loh (author)
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Rashid, Abdul (author)
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Studnicka, Michael (author)
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Nafees, Asaad A (author)
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Seemungal, Terence (author)
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Aquart-Stewart, Althea (author)
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Al Ghobain, Mohammed (author)
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Zheng, Jinping (author)
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Juvekar, Sanjay (author)
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Salvi, Sundeep (author)
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- Jogi, Rain (author)
- Uppsala universitet,Lung- allergi- och sömnforskning,Tartu Univ Hosp, Lung Clin, Tartu, Estonia
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Mannino, David (author)
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Gislason, Thorarinn (author)
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Buist, A Sonia (author)
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Cullinan, Paul (author)
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Burney, Peter (author)
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(creator_code:org_t)
- 2022-08-25
- 2023
- English.
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In: European Respiratory Journal. - : European Respiratory Society. - 0903-1936 .- 1399-3003. ; 61:1
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Background Chronic obstructive pulmonary disease has been associated with exposures in the workplace. We aimed to assess the association of respiratory symptoms and lung function with occupation in the Burden of Obstructive Lung Disease study.Methods We analysed cross-sectional data from 28 823 adults (≥40 years) in 34 countries. We considered 11 occupations and grouped them by likelihood of exposure to organic dusts, inorganic dusts and fumes. The association of chronic cough, chronic phlegm, wheeze, dyspnoea, forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1)/FVC with occupation was assessed, per study site, using multivariable regression. These estimates were then meta-analysed. Sensitivity analyses explored differences between sexes and gross national income.Results Overall, working in settings with potentially high exposure to dusts or fumes was associated with respiratory symptoms but not lung function differences. The most common occupation was farming. Compared to people not working in any of the 11 considered occupations, those who were farmers for ≥20 years were more likely to have chronic cough (OR 1.52, 95% CI 1.19–1.94), wheeze (OR 1.37, 95% CI 1.16–1.63) and dyspnoea (OR 1.83, 95% CI 1.53–2.20), but not lower FVC (β=0.02 L, 95% CI −0.02–0.06 L) or lower FEV1/FVC (β=0.04%, 95% CI −0.49–0.58%). Some findings differed by sex and gross national income.Conclusion At a population level, the occupational exposures considered in this study do not appear to be major determinants of differences in lung function, although they are associated with more respiratory symptoms. Because not all work settings were included in this study, respiratory surveillance should still be encouraged among high-risk dusty and fume job workers, especially in low- and middle-income countries.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
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- art (subject category)
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- By the author/editor
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Ratanachina, Jat ...
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Amaral, Andre F. ...
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De Matteis, Sara
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Lawin, Herve
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Mortimer, Kevin
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Obaseki, Daniel ...
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show more...
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Harrabi, Imed
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Denguezli, Meria ...
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Wouters, Emiel F ...
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Janson, Christer
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Nielsen, Rune
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Gulsvik, Amund
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Hacene Cherkaski ...
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Mejza, Filip
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Padukudru Anand, ...
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Elsony, Asma
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Ahmed, Rana
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Tan, Wan
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Li Cher, Loh
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Rashid, Abdul
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Studnicka, Micha ...
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Nafees, Asaad A
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Seemungal, Teren ...
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Aquart-Stewart, ...
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Al Ghobain, Moha ...
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Zheng, Jinping
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Juvekar, Sanjay
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Salvi, Sundeep
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Jogi, Rain
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Mannino, David
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Gislason, Thorar ...
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Buist, A Sonia
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Cullinan, Paul
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Burney, Peter
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
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European Respira ...
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Uppsala University