Search: (WFRF:(Eliassen Heather)) pers:(Brenner Hermann) pers:(Pharoah Paul D. P.) >
Aggregation tests i...
-
Mueller, Stefanie H.UCL, Inst Hlth Informat, London, England.,University College London
(author)
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry
- Article/chapterEnglish2023
Publisher, publication year, extent ...
-
2023-01-26
-
BioMed Central (BMC),2023
-
electronicrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-498948
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-498948URI
-
https://doi.org/10.1186/s13073-022-01152-5DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:152000895URI
-
https://lup.lub.lu.se/record/03b290d6-d650-490a-9e52-2fcb867a25b3URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Background: Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes.Methods: We evaluated the potential of gene-based aggregation in the Breast Cancer Association Consortium cohorts including 83,471 cases and 59,199 controls. Low-frequency variants were aggregated for individual genes' coding and regulatory regions. Association results in European ancestry samples were compared to single-marker association results in the same cohort. Gene-based associations were also combined in meta-analysis across individuals with European, Asian, African, and Latin American and Hispanic ancestry.Results: In European ancestry samples, 14 genes were significantly associated (q < 0.05) with BC. Of those, two genes, FMNL3 (P = 6.11 x 10(-6)) and AC058822.1 (P = 1.47 x 10(-4)), represent new associations. High FMNL3 expression has previously been linked to poor prognosis in several other cancers. Meta-analysis of samples with diverse ancestry discovered further associations including established candidate genes ESR1 and CBLB. Furthermore, literature review and database query found further support for a biologically plausible link with cancer for genes CBLB, FMNL3, FGFR2, LSP1, MAP3K1, and SRGAP2C.Conclusions: Using extended gene-based aggregation tests including coding and regulatory variation, we report identification of plausible target genes for previously identified single-marker associations with BC as well as the discovery of novel genes implicated in BC development. Including multi ancestral cohorts in this study enabled the identification of otherwise missed disease associations as ESR1 (P = 1.31 x 10(-5)), demonstrating the importance of diversifying study cohorts.
Subject headings and genre
-
MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Medicinsk genetik hsv//swe
-
MEDICAL AND HEALTH SCIENCES Basic Medicine Medical Genetics hsv//eng
-
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
-
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
-
Breast cancer susceptibility
-
Diverse ancestry
-
Rare variants
-
Gene regulation
-
Genome-wide association study
-
Breast cancer susceptibility
-
Diverse ancestry
-
Gene regulation
-
Genome-wide association study
-
Rare variants
-
African
-
ancestry group
-
Article
-
Asian
-
boredom susceptibility
-
breast cancer
-
cancer prognosis
-
CBLB gene
-
cohort analysis
-
controlled study
-
ESR1 gene
-
European
-
FGFR2 gene
-
FMNL3 gene
-
gene base aggregation
-
gene expression level
-
gene structure
-
genetic association
-
genetic association study
-
genetic code
-
genetic variability
-
Hispanic
-
human
-
human cell
-
human tissue
-
LSP1 gene
-
major clinical study
-
MAP3K1 gene
-
meta analysis (topic)
-
South and Central America
-
SRGAP2C gene
-
statistical significance
-
tumor-related gene
-
Black person
-
breast tumor
-
female
-
genetic predisposition
-
genetic screening
-
genetics
-
genome-wide association study
-
meta analysis
-
procedures
-
single nucleotide polymorphism
-
FMNL3 protein, human
-
methenamine
-
Black People
-
Breast Neoplasms
-
Female
-
Formins
-
Genetic Predisposition to Disease
-
Genetic Testing
-
Genome-Wide Association Study
-
Humans
-
Polymorphism, Single Nucleotide
Added entries (persons, corporate bodies, meetings, titles ...)
-
Lai, Alvina G.UCL, Inst Hlth Informat, London, England.
(author)
-
Valkovskaya, MariaUCL, Div Psychiat, London, England.
(author)
-
Michailidou, KyriakiCyprus Inst Neurol & Genet, Biostat Unit, CY-2371 Nicosia, Cyprus.;Cyprus Inst Neurol & Genet, Cyprus Sch Mol Med, CY-2371 Nicosia, Cyprus.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.
(author)
-
Bolla, Manjeet K.Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.
(author)
-
Wang, QinUniv Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.
(author)
-
Dennis, JoeUniv Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.
(author)
-
Lush, MichaelUniv Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.
(author)
-
Abu-Ful, ZomorudaCarmel Hosp, Clalit Natl Canc Control Ctr, IL-35254 Haifa, Israel.;Technion Fac Med, IL-35254 Haifa, Israel.
(author)
-
Ahearn, Thomas U.NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.
(author)
-
Andrulis, Irene L.Lunenfeld Tanenbaum Res Inst Mt Sinai Hosp, Fred A Litwin Ctr Canc Genet, Toronto, ON M5G 1X5, Canada.;Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada.
(author)
-
Anton-Culver, HodaUniv Calif Irvine, Genet Epidemiol Res Inst, Dept Med, Irvine, CA 92617 USA.
(author)
-
Antonenkova, Natalia N.NN Alexandrov Res Inst Oncol & Med Radiol, Minsk 223040, BELARUS.
(author)
-
Arndt, VolkerGerman Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany.
(author)
-
Aronson, Kristan J.Queens Univ, Canc Res Inst, Dept Publ Hlth Sci, Kingston, ON K7L 3N6, Canada.
(author)
-
Augustinsson, A.Lund University,Lunds universitet,Karolinska Institutet,Vård i högteknologisk miljö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Cancerepidemiologi & strål,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Care in high technological environments,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Cancerepidemiology and radiation,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-aea
(author)
-
Baert, ThaisUniv Hosp Leuven, Leuven Multidisciplinary Breast Ctr, Leuven Canc Inst, Dept Oncol, B-3000 Louvain, Belgium.
(author)
-
Freeman, Laura E. BeaneNCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.
(author)
-
Beckmann, Matthias W.Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.
(author)
-
Behrens, SabineGerman Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.
(author)
-
Benitez, JavierBiomed Network Rare Dis CIBERER, Madrid 28029, Spain.;Spanish Natl Canc Res Ctr CNIO, Human Canc Genet Programme, Madrid 28029, Spain.
(author)
-
Bermisheva, MarinaRussian Acad Sci, Inst Biochem & Genet, Ufa Fed Res Ctr, Ufa 450054, Russia.
(author)
-
Blomqvist, CarlUniv Helsinki, Helsinki Univ Hosp, Dept Oncol, Helsinki 00290, Finland.;Örebro Univ Hosp, Dept Oncol, S-70185 Örebro, Sweden.
(author)
-
Bogdanova, Natalia, VNN Alexandrov Res Inst Oncol & Med Radiol, Minsk 223040, BELARUS.;Hannover Med Sch, Depart Ment Radiat Oncol, D-30625 Hannover, Germany.;Hannover Med Sch, Gynaecol Res Unit, D-30625 Hannover, Germany.
(author)
-
Bojesen, Stig E.Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Copenhagen Gen Populat Study, DK-2730 Herlev, Denmark.;Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2730 Herlev, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, DK-2200 Copenhagen, Denmark.
(author)
-
Bonanni, BernardoEuropean Inst Oncol IRCCS, Div Canc Prevent & Genet, IEO, I-20141 Milan, Italy.,University College London
(author)
-
Brenner, HermannGerman Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany.;German Canc Res Ctr, Natl Ctr Tumor Dis NCT, Div Prevent Oncol, D-69120 Heidelberg, Germany.;German Canc Res Ctr, German Canc Consortium DKTK, D-69120 Heidelberg, Germany.
(author)
-
Brucker, Sara Y.Univ Tubingen, Dept Gynecol & Obstet, D-72076 Tubingen, Germany.
(author)
-
Buys, Saundra S.Huntsman Canc Inst, Dept Med, Salt Lake City, UT 84112 USA.
(author)
-
Castelao, Jose E.Inst Invest Sanitaria Galicia Sur IISGS, Oncol & Genet Unit, Xerencia Xest Integrada Vigo SERGAS, Vigo 36312, Spain.
(author)
-
Chan, Tsun L.Hong Kong Hereditary Breast Canc Family Registry, Hong Kong, Peoples R China.;Hong Kong Sanat & Hosp, Dept Mol Pathol, Hong Kong, Peoples R China.
(author)
-
Chang-Claude, JennyGerman Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.;Univ Canc Ctr Hamburg UCCH, Univ Med Ctr Hamburg Eppendorf, Canc Epidemiol Grp, D-20246 Hamburg, Germany.
(author)
-
Chanock, Stephen J.NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.
(author)
-
Choi, Ji-YeobSeoul Natl Univ, Dept Biomed Sci, Grad Sch, Seoul 03080, South Korea.;Seoul Natl Univ, Canc Res Inst, Seoul 03080, South Korea.;Seoul Natl Univ, Inst Hlth Policy & Management, Med Res Ctr, Seoul 03080, South Korea.
(author)
-
Chung, Wendy K.Karolinska Institutet
(author)
-
Colonna, Sarah, VHuntsman Canc Inst, Dept Med, Salt Lake City, UT 84112 USA.
(author)
-
Cornelissen, StenNetherlands Canc Inst, Div Mol Pathol, Antoni Van Leeuwenhoek Hosp, NL-1066 CX Amsterdam, Netherlands.
(author)
-
Couch, Fergus J.Mayo Clin, Dept Lab Med & Pathol, Rochester, MN 55905 USA.
(author)
-
Czene, KamilaKarolinska Institutet
(author)
-
Daly, Mary B.Fox Chase Canc Ctr, Dept Clin Genet, Philadelphia, PA 19111 USA.
(author)
-
Devilee, PeterLeiden Univ Med Ctr, Dept Pathol, NL-2333 ZA Leiden, Netherlands.;Leiden Univ Med Ctr, Dept Human Genet, NL-2333 ZA Leiden, Netherlands.
(author)
-
Dork, ThiloHannover Med Sch, Gynaecol Res Unit, D-30625 Hannover, Germany.
(author)
-
Dossus, LaureInt Agcy Res Canc IARC WHO, Nutr & Metab Sect, F-69372 Lyon, France.
(author)
-
Dwek, MiriamUniv Westminster, Sch Life Sci, London W1W 6UW, England.
(author)
-
Eccles, Diana M.Univ Southampton, Fac Med, Southampton SO17 1BJ, Hants, England.
(author)
-
Ekici, Arif B.Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Inst Human Genet, D-91054 Erlangen, Germany.
(author)
-
Eliassen, A. HeatherHarvard Med Sch, Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA.;Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.
(author)
-
Engel, ChristophUniv Leipzig, Inst Med Informat Stat & Epidemiol, D-04107 Leipzig, Germany.;Univ Leipzig, LIFE Leipzig Res Ctr Civilizat Dis, D-04103 Leipzig, Germany.
(author)
-
Evans, D. GarethUniv Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol, Sch Biol Sci, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Manchester Ctr Genom Med, North West Genom Lab Hub,St Marys Hosp, Manchester, Lancs, England.
(author)
-
Fasching, Peter A.Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.;Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Hematol & Oncol, Los Angeles, CA 90095 USA.
(author)
-
Fletcher, OliviaBreast Canc Now Toby Robins Res Ctr, Inst Canc Res, London SW7 3RP, England.
(author)
-
Flyger, HenrikCopenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Breast Surg, DK-2730 Herlev, Denmark.
(author)
-
Gago-Dominguez, ManuelaComplejo Hosp Univ Santiago, Inst Invest Sanitaria Santiago Compostela IDIS, SERGAS, Fdn Poebl Galega Med Xenom, Santiago De Compostela 15706, Spain.;Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92037 USA.
(author)
-
Gao, Yu-TangShanghai Canc Inst, Dept Epidemiol, Shanghai 20032, Peoples R China.
(author)
-
Garcia-Closas, MontserratNCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.
(author)
-
Garcia-Saenz, Jose A.Hosp Clin San Carlos, Ctr Invest Biomed Red Canc CIBERONC, Inst Invest Sanitaria San Carlos IdISSC, Med Oncol Dept, Madrid 28040, Spain.
(author)
-
Genkinger, JeanineColumbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY 10032 USA.
(author)
-
Gentry-Maharaj, AleksandraUCL, Inst Clin Trials & Methodol, London WC1V 6LJ, England.
(author)
-
Grassmann, FelixKarolinska Institutet
(author)
-
Guenel, PascalUniv Paris Saclay, Ctr Res Epidemiol & Populat Hlth CESP, INSERM, Team Exposome & Hered, F-94805 Villejuif, France.
(author)
-
Gundert, MelanieGerman Canc Res Ctr, Mol Epidemiol Grp, C08069120, Heidelberg, Germany.;Heidelberg Univ, Univ Womens Clin Heidelberg, Mol Biol Breast Canc, D-69120 Heidelberg, Germany.;Helmholtz Zentrum Munchen, Inst Diabet Res, German Res Ctr Environm Hlth, D-85764 Neuherberg, Germany.
(author)
-
Haeberle, LotharFriedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.
(author)
-
Hahnen, EricUniv Cologne, Univ Hosp Cologne, Fac Med, Ctr Familial Breast & Ovarian Canc, D-50937 Cologne, Germany.;Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Integrated Oncol CIO, D-50937 Cologne, Germany.
(author)
-
Haiman, Christopher A.Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90033 USA.
(author)
-
Hakansson, NiclasKarolinska Institutet
(author)
-
Hall, PerKarolinska Institutet
(author)
-
Harkness, Elaine F.Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol, Div Informat, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Wythenshawe Hosp, Nightingale & Genesis Prevent Ctr, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, NIHR Manchester Biomed Res Unit, Manchester, Lancs, England.
(author)
-
Harrington, Patricia A.Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.
(author)
-
Hartikainen, Jaana M.Univ Eastern Finland, Translat Canc Res Area, Kuopio 70210, Finland.;Univ Eastern Finland, Inst Clin Med Pathol & Forens Med, Kuopio 70210, Finland.
(author)
-
Hartman, MikaelNatl Univ Singapore, Natl Univ Hlth Syst, Saw Swee Hock Sch Publ Hlth, Singapore 119077, Singapore.;Natl Univ Hlth Syst, Dept Surg, Singapore 119228, Singapore.
(author)
-
Hein, AlexanderFriedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.
(author)
-
Ho, Weang-KeeUniv Nottingham, Dept Math Sci, Fac Sci & Engn, Malaysia Campus, Semenyih 43500, Selangor, Malaysia.;Canc Res Malaysia, Breast Canc Res Programme, Subang Jaya 47500, Selangor, Malaysia.
(author)
-
Hooning, Maartje J.Erasmus MC Canc Inst, Dept Med Oncol, NL-3015 GD Rotterdam, Netherlands.
(author)
-
Hoppe, ReinerDr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany.;Univ Tubingen, D-72074 Tubingen, Germany.
(author)
-
Hopper, John L.Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Melbourne, Vic 3010, Australia.
(author)
-
Houlston, Richard S.Inst Canc Res, Div Genet & Epidemiol Ogy, London SM2 5NG, England.
(author)
-
Howell, AnthonyUniv Manchester, Div Canc Sci, Manchester M13 9PL, Lancs, England.
(author)
-
Hunter, David J.Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Univ Oxford, Nuffield Dept Populat Hlth, Oxford OX3 7LF, England.
(author)
-
Huo, DezhengUniv Chicago, Ctr Clin Canc Genet, Chicago, IL 60637 USA.
(author)
-
Investigators, AbctbUniv Sydney, Westmead Inst Med Res, Australian Breast Canc Tissue Bank, Sydney, NSW 2145, Australia.
(author)
-
Ito, HidemiAichi Canc Ctr Res Inst, Div Canc Informat & Control, Nagoya, Aichi 4648681, Japan.;Nagoya Univ, Div Canc Epidemiol, Grad Sch Med, Nagoya, Aichi 4668550, Japan.
(author)
-
Iwasaki, MotokiNatl Canc Ctr Inst Canc Control, Ctr Publ Hlth Sci, Div Epidemiol, Tokyo 1040045, Japan.
(author)
-
Jakubowska, AnnaPomeranian Med Univ, Dept Genet & Pathol, PL-71252 Szczecin, Poland.;Pomeranian Med Univ, Independent Lab Mol Biol & Genet Diagnost, PL-71252 Szczecin, Poland.
(author)
-
Janni, WolfgangUniv Hosp Ulm, Dept Gynaecol & Obstet, D-89075 Ulm, Germany.
(author)
-
John, Esther M.Stanford Univ, Sch Med, Dept Epidemiol & Populat Hlth, Stanford, CA 94305 USA.;Stanford Univ, Sch Med, Stanford Canc Inst, Dept Med, Stanford, CA 94304 USA.
(author)
-
Jones, Michael E.Inst Canc Res, Div Genet & Epidemiol Ogy, London SM2 5NG, England.
(author)
-
Jung, AudreyGerman Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.
(author)
-
Kaaks, RudolfGerman Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.
(author)
-
Kang, DaeheeSeoul Natl Univ, Canc Res Inst, Seoul 03080, South Korea.;Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul 03080, South Korea.
(author)
-
Khusnutdinova, Elza K.Russian Acad Sci, Inst Biochem & Genet, Ufa Fed Res Ctr, Ufa 450054, Russia.;Bashkir State Univ, Dept Genet & Fundamental Med, Ufa 450000, Russia.
(author)
-
Kim, Sung-WonDaerim St Marys Hosp, Dept Surg, Seoul 07442, South Korea.
(author)
-
Kitahara, Cari M.NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(author)
-
Koutros, StellaNCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.
(author)
-
Kraft, PeterHarvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, Boston, MA 02115 USA.
(author)
-
Kristensen, Vessela N.Univ Oslo, Fac Med, Inst Clin Med, N-0450 Oslo, Norway. Vestre Viken Hosp, Dept Res, N-3019 Drammen, Norway. Oslo Univ Hosp Ullev, Dept Canc, Div Surg, Sect Breast & Endocrine Surg, N-0450 Oslo, Norway. Oslo Univ Hosp, Dept Radiol & Nucl Med, N-0379 Oslo, Norway. Akershus Univ Hosp, Dept Pathol, N-1478 Lorenskog, Norway. Oslo Univ Hosp, Inst Canc Res, Dept Tumor Biol, N-0379 Oslo, Norway. Oslo Univ Hosp, Dept Oncol, Div Surg Canc & Transplantat Med, Radiumhosp, N-0379 Oslo, Norway. Oslo Univ Hosp, Natl Advisory Unit Late Effects Canc Treatment, N-0379 Oslo, Norway. Akershus Univ Hosp, Dept Oncol, N-1478 Lorenskog, Norway. Oslo Univ Hosp, Oslo Breast Canc Res Consortium, N-0379 Oslo, Norway.;Oslo Univ Hosp, Dept Med Genet, N-0379 Oslo, Norway.;Univ Oslo, N-0379 Oslo, Norway.
(author)
-
Kubelka-Sabit, KaterinaClin Hosp Acibadem Sistina, Dept Histopathol & Cytol, Skopje 1000, North Macedonia.
(author)
-
Kurian, Allison W.Stanford Univ, Sch Med, Dept Epidemiol & Populat Hlth, Stanford, CA 94305 USA.;Stanford Univ, Sch Med, Stanford Canc Inst, Dept Med, Stanford, CA 94304 USA.
(author)
-
Kwong, AvaHong Kong Hereditary Breast Canc Family Registry, Hong Kong, Peoples R China.;Univ Hong Kong, Dept Surg, Hong Kong, Peoples R China.;Hong Kong Sanat & Hosp, Dept Surg, Hong Kong, Peoples R China.;Hong Kong Sanat & Hosp, Canc Genet Ctr, Hong Kong, Peoples R China.
(author)
-
Lacey, James, VCity Hope Natl Med Ctr, Depart Ment Computat & Quantitat Med, Duarte, CA 91010 USA.;City Hope Natl Med Ctr, City Hope Comprehens Canc Ctr, Duarte, CA 91010 USA.
(author)
-
Lambrechts, DietherVIB Ctr Canc Biol, B-3001 Louvain, Belgium.;Univ Leuven, Dept Human Genet, Lab Translat Genet, B-3000 Louvain, Belgium.
(author)
-
Le Marchand, LoicUniv Hawaii Canc Ctr, Epidemiol Program, Honolulu, HI 96813 USA.
(author)
-
Li, JingmeiGenome Inst Singapore, Human Genet Div, Singapore 138672, Singapore.
(author)
-
Linet, MarthaNCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(author)
-
Lo, Wing-YeeDr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany.;Univ Tubingen, D-72074 Tubingen, Germany.
(author)
-
Long, JirongVanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Dept Med,Sch Med, Nashville, TN 37232 USA.
(author)
-
Lophatananon, ArtitayaUniv Manchester, Fac Biol, Sch Hlth Sci, Div Populat Hlth Hlth Serv Res & Primary Care, Manchester M13 9PL, Lancs, England.
(author)
-
Mannermaa, ArtoUniv Eastern Finland, Translat Canc Res Area, Kuopio 70210, Finland.;Univ Eastern Finland, Inst Clin Med Pathol & Forens Med, Kuopio 70210, Finland.;Kuopio Univ Hosp, Biobank Eastern Finland, Kuopio, Finland.
(author)
-
Manoochehri, MehdiGerman Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.
(author)
-
Margolin, SaraKarolinska Institutet
(author)
-
Matsuo, KeitaroNagoya Univ, Div Canc Epidemiol, Grad Sch Med, Nagoya, Aichi 4668550, Japan.;Aichi Canc Ctr Res Inst, Div Canc Epidemiol & Prevent, Nagoya, Aichi 4648681, Japan.
(author)
-
Mavroudis, DimitriosUniv Hosp Heraklion, Dept Med Oncol, Iraklion 71110, Greece.
(author)
-
Menon, UshaUCL, Inst Clin Trials & Methodol, London WC1V 6LJ, England.
(author)
-
Muir, KennethUniv Manchester, Fac Biol, Sch Hlth Sci, Div Populat Hlth Hlth Serv Res & Primary Care, Manchester M13 9PL, Lancs, England.
(author)
-
Murphy, Rachel A.Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC V6T 1Z4, Canada.;BC Canc, Canc Control Res, Vancouver, BC V5Z 1L3, Canada.
(author)
-
Nevanlinna, HeliUniv Helsinki, Helsinki Univ Hosp, Dept Obstet & Gynecol, Helsinki 00290, Finland.
(author)
-
Newman, William G.Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol, Sch Biol Sci, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Manchester Ctr Genom Med, North West Genom Lab Hub,St Marys Hosp, Manchester, Lancs, England.
(author)
-
Niederacher, DieterHeinrich Heine Univ Dusseldorf, Univ Hosp Dusseldorf, Dept Gynecol & Obstet, D-40225 Dusseldorf, Germany.
(author)
-
O'Brien, Katie M.NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA.
(author)
-
Obi, NadiaUniv Med Ctr Hamburg Eppendorf, Inst Med Biometry & Epidemiol, D-20246 Hamburg, Germany.
(author)
-
Offit, KennethMem Sloan Kettering Canc Ctr, Dept Canc Biol & Genet, Clin Genet Res Lab, New York, NY 10065 USA.;Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, New York, NY 10065 USA.
(author)
-
Olopade, Olufunmilayo, IUniv Chicago, Ctr Clin Canc Genet, Chicago, IL 60637 USA.
(author)
-
Olshan, Andrew F.Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.;Univ North Carolina Chapel Hill, UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.
(author)
-
Olsson, H.Lund University,Lunds universitet,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund Melanoma Study Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)onk-hol
(author)
-
Park, Sue K.Seoul Natl Univ, Canc Res Inst, Seoul 03080, South Korea.;Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul 03080, South Korea.;Seoul Natl Univ, Coll Med, Integrated Major Innovat Med Sci, Seoul 03080, South Korea.
(author)
-
Patel, Alpa, VAmer Canc Soc, Dept Populat Sci, Atlanta, GA 30303 USA.
(author)
-
Patel, AchalUniv North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.;Univ North Carolina Chapel Hill, UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.
(author)
-
Perou, Charles M.Univ North Carolina Chapel Hill, Dept Genet, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.
(author)
-
Peto, JulianLondon Sch Hyg & Trop Med, Dept Noncommunicable Dis Epidemiol, London WC1E 7HT, England.
(author)
-
Pharoah, Paul D. P.Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.
(author)
-
Plaseska-Karanfilska, DijanaMASA, Res Ctr Genet Engn & Biotechnol Georgi D Efremov, Skopje 1000, North Macedonia.
(author)
-
Presneau, NadegeUniv Westminster, Sch Life Sci, London W1W 6UW, England.
(author)
-
Rack, BrigitteUniv Hosp Ulm, Dept Gynaecol & Obstet, D-89075 Ulm, Germany.
(author)
-
Radice, PaoloFdn IRCCS Ist Nazl Tumori INT, Dept Res, Unit Mol Bases Genet Risk & Genet Testing, I-20133 Milan, Italy.
(author)
-
Ramachandran, DhanyaHannover Med Sch, Gynaecol Res Unit, D-30625 Hannover, Germany.
(author)
-
Rashid, Muhammad U.German Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.;Shaukat Khanum Mem Canc Hosp & Res Ctr SKMCH & RC, Dept Basic Sci, Lahore 54000, Pakistan.
(author)
-
Rennert, GadCarmel Hosp, Clalit Natl Canc Control Ctr, IL-35254 Haifa, Israel.;Technion Fac Med, IL-35254 Haifa, Israel.
(author)
-
Romero, AtochaHosp Univ Puerta de Hierro, Med Oncol Dept, Madrid 28222, Spain.
(author)
-
Ruddy, Kathryn J.Mayo Clin, Dept Oncol, Rochester, MN 55905 USA.
(author)
-
Ruebner, MatthiasFriedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.
(author)
-
Saloustros, EmmanouilUniv Hosp Larissa, Dept Oncol, Larisa 41110, Greece.
(author)
-
Sandler, Dale P.NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA.
(author)
-
Sawyer, Elinor J.Kings Coll London, Comprehens Canc Ctr, Sch Canc & Pharmaceut Sci, Guys Campus, London, England.
(author)
-
Schmidt, Marjanka K.Netherlands Canc Inst, Div Mol Pathol, Antoni Van Leeuwenhoek Hosp, NL-1066 CX Amsterdam, Netherlands.;Antoni Van Leeuwenhoek Hosp, Div Psychosocial Res & Epidemiol, Netherlands Canc Inst, NL-1066 CX Amsterdam, Netherlands.
(author)
-
Schmutzler, Rita K.Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Familial Breast & Ovarian Canc, D-50937 Cologne, Germany.;Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Integrated Oncol CIO, D-50937 Cologne, Germany.;Univ Cologne, Fac Med, Ctr Mol Med Cologne CMMC, D-50931 Cologne, Germany.;Univ Cologne, Univ Hosp Cologne, D-50931 Cologne, Germany.
(author)
-
Schneider, Michael O.Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.
(author)
-
Scott, ChristopherMayo Clin, Dept Hlth Sci Res, Rochester, MN 55905 USA.
(author)
-
Shah, MitulUniv Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.
(author)
-
Sharma, PriyankaUniv Kansas Med Ctr, Dept Internal Med, Div Med Oncol, Westwood, KS 66205 USA.
(author)
-
Shen, Chen-YangAcad Sinica, Inst Biomed Sci, Taipei 115, Taiwan.;China Med Univ, Sch Publ Hlth, Taichung, Taiwan.
(author)
-
Shu, Xiao-OuVanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Dept Med,Sch Med, Nashville, TN 37232 USA.
(author)
-
Simard, JacquesCtr Hosp Univ Quebec Univ Laval Res Ctr, Genom Ctr, Quebec City, PQ G1V 4G2, Canada.
(author)
-
Surowy, HaraldGerman Canc Res Ctr, Mol Epidemiol Grp, C08069120, Heidelberg, Germany.;Heidelberg Univ, Univ Womens Clin Heidelberg, Mol Biol Breast Canc, D-69120 Heidelberg, Germany.
(author)
-
Tamimi, Rulla M.Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Weill Cornell Med, Dept Populat Hlth Sci, New York, NY 10065 USA.
(author)
-
Tapper, William J.Univ Southampton, Fac Med, Southampton SO17 1BJ, Hants, England.
(author)
-
Taylor, Jack A.NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA.;NIEHS, Epigenet & Stem Cell Biol Lab, NIH, Res Triangle Pk, NC 27709 USA.
(author)
-
Teo, Soo HwangCanc Res Malaysia, Breast Canc Res Programme, Subang Jaya 47500, Selangor, Malaysia.;Univ Malaya, Fac Med, Dept Surg, Kuala Lumpur 50603, Malaysia.
(author)
-
Teras, Lauren R.Amer Canc Soc, Dept Populat Sci, Atlanta, GA 30303 USA.
(author)
-
Toland, Amanda E.Ohio State Univ, Dept Canc Biol & Genet, Columbus, OH 43210 USA.
(author)
-
Tollenaar, Rob A. E. M.Leiden Univ Med Ctr, Dept Surg, NL-2333 ZA Leiden, Netherlands.
(author)
-
Torres, DianaGerman Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.;Pontificia Univ Javeriana, Inst Human Genet, Bogota 110231, Colombia.
(author)
-
Torres-Mejia, GabrielaCtr Populat Hlth Res, Natl Inst Publ Hlth, Cuernavaca 62100, Morelos, Mexico.
(author)
-
Troester, Melissa A.Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.;Univ North Carolina Chapel Hill, UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.
(author)
-
Truong, ThereseUniv Paris Saclay, Ctr Res Epidemiol & Populat Hlth CESP, INSERM, Team Exposome & Hered, F-94805 Villejuif, France.
(author)
-
Vachon, Celine M.Mayo Clin, Div Epidemiol, Dept Quantitat Hlth Sci, Rochester, MN 55905 USA.
(author)
-
Vijai, JosephMem Sloan Kettering Canc Ctr, Dept Canc Biol & Genet, Clin Genet Res Lab, New York, NY 10065 USA.;Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, New York, NY 10065 USA.
(author)
-
Weinberg, Clarice R.NIEHS, Biostat & Computat Biol Branch, NIH, Res Triangle Pk, NC 27709 USA.
(author)
-
Wendt, CamillaKarolinska Inst, Dept Clin Sci & Educ, Sodersjukhuset, S-11883 Stockholm, Sweden.
(author)
-
Winqvist, RobertUniv Oulu, Bioctr Oulu, Canc & Translat Med Res Unit, Lab Canc Genet & Tumor Biol, Oulu 90570, Finland.;Northern Finland Lab Ctr Oulu, Lab Canc Genet & Tumor Biol, Oulu 90570, Finland.
(author)
-
Wolk, AlicjaUppsala universitet,Institutionen för kirurgiska vetenskaper,Karolinska Inst, Inst Environm Med, S-17177 Stockholm, Sweden.(Swepub:uu)alwol516
(author)
-
Wu, Anna H.Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90033 USA.
(author)
-
Yamaji, TaikiNatl Canc Ctr Inst Canc Control, Ctr Publ Hlth Sci, Div Epidemiol, Tokyo 1040045, Japan.
(author)
-
Yang, Xiaohong R.NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.
(author)
-
Yu, Jyh-CherngTriserv Gen Hosp, Natl Def Med Ctr, Dept Surg, Taipei 114, Taiwan.
(author)
-
Zheng, WeiVanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Dept Med,Sch Med, Nashville, TN 37232 USA.
(author)
-
Ziogas, ArgyriosUniv Calif Irvine, Genet Epidemiol Res Inst, Dept Med, Irvine, CA 92617 USA.
(author)
-
Ziv, EladUniv Calif San Francisco, Diller Family Comprehens Canc Ctr, Inst Human Genet, Dept Med, San Francisco, CA 94115 USA.
(author)
-
Dunning, Alison M.Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.
(author)
-
Easton, Douglas F.Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.
(author)
-
Hemingway, HarryUCL, Inst Hlth Informat, London, England.;UCL, Hlth Data Res UK, London, England.;Univ Coll London Hosp, Biomed Res Ctr UCLH BRC, London, England.;Alan Turing Inst, London, England.
(author)
-
Hamann, UteGerman Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.
(author)
-
Kuchenbaecker, Karoline B.UCL, Div Psychiat, London, England.;UCL, UCL Genet Inst, London, England.
(author)
-
UCL, Inst Hlth Informat, London, England.University College London
(creator_code:org_t)
Related titles
-
In:Genome Medicine: BioMed Central (BMC)151756-994X
Internet link
Find in a library
To the university's database
- By the author/editor
-
Mueller, Stefani ...
-
Lai, Alvina G.
-
Valkovskaya, Mar ...
-
Michailidou, Kyr ...
-
Bolla, Manjeet K ...
-
Wang, Qin
-
show more...
-
Dennis, Joe
-
Lush, Michael
-
Abu-Ful, Zomorud ...
-
Ahearn, Thomas U ...
-
Andrulis, Irene ...
-
Anton-Culver, Ho ...
-
Antonenkova, Nat ...
-
Arndt, Volker
-
Aronson, Kristan ...
-
Augustinsson, A.
-
Baert, Thais
-
Freeman, Laura E ...
-
Beckmann, Matthi ...
-
Behrens, Sabine
-
Benitez, Javier
-
Bermisheva, Mari ...
-
Blomqvist, Carl
-
Bogdanova, Natal ...
-
Bojesen, Stig E.
-
Bonanni, Bernard ...
-
Brenner, Hermann
-
Brucker, Sara Y.
-
Buys, Saundra S.
-
Castelao, Jose E ...
-
Chan, Tsun L.
-
Chang-Claude, Je ...
-
Chanock, Stephen ...
-
Choi, Ji-Yeob
-
Chung, Wendy K.
-
Colonna, Sarah, ...
-
Cornelissen, Ste ...
-
Couch, Fergus J.
-
Czene, Kamila
-
Daly, Mary B.
-
Devilee, Peter
-
Dork, Thilo
-
Dossus, Laure
-
Dwek, Miriam
-
Eccles, Diana M.
-
Ekici, Arif B.
-
Eliassen, A. Hea ...
-
Engel, Christoph
-
Evans, D. Gareth
-
Fasching, Peter ...
-
Fletcher, Olivia
-
Flyger, Henrik
-
Gago-Dominguez, ...
-
Gao, Yu-Tang
-
Garcia-Closas, M ...
-
Garcia-Saenz, Jo ...
-
Genkinger, Jeani ...
-
Gentry-Maharaj, ...
-
Grassmann, Felix
-
Guenel, Pascal
-
Gundert, Melanie
-
Haeberle, Lothar
-
Hahnen, Eric
-
Haiman, Christop ...
-
Hakansson, Nicla ...
-
Hall, Per
-
Harkness, Elaine ...
-
Harrington, Patr ...
-
Hartikainen, Jaa ...
-
Hartman, Mikael
-
Hein, Alexander
-
Ho, Weang-Kee
-
Hooning, Maartje ...
-
Hoppe, Reiner
-
Hopper, John L.
-
Houlston, Richar ...
-
Howell, Anthony
-
Hunter, David J.
-
Huo, Dezheng
-
Investigators, A ...
-
Ito, Hidemi
-
Iwasaki, Motoki
-
Jakubowska, Anna
-
Janni, Wolfgang
-
John, Esther M.
-
Jones, Michael E ...
-
Jung, Audrey
-
Kaaks, Rudolf
-
Kang, Daehee
-
Khusnutdinova, E ...
-
Kim, Sung-Won
-
Kitahara, Cari M ...
-
Koutros, Stella
-
Kraft, Peter
-
Kristensen, Vess ...
-
Kubelka-Sabit, K ...
-
Kurian, Allison ...
-
Kwong, Ava
-
Lacey, James, V
-
Lambrechts, Diet ...
-
Le Marchand, Loi ...
-
Li, Jingmei
-
Linet, Martha
-
Lo, Wing-Yee
-
Long, Jirong
-
Lophatananon, Ar ...
-
Mannermaa, Arto
-
Manoochehri, Meh ...
-
Margolin, Sara
-
Matsuo, Keitaro
-
Mavroudis, Dimit ...
-
Menon, Usha
-
Muir, Kenneth
-
Murphy, Rachel A ...
-
Nevanlinna, Heli
-
Newman, William ...
-
Niederacher, Die ...
-
O'Brien, Katie M ...
-
Obi, Nadia
-
Offit, Kenneth
-
Olopade, Olufunm ...
-
Olshan, Andrew F ...
-
Olsson, H.
-
Park, Sue K.
-
Patel, Alpa, V
-
Patel, Achal
-
Perou, Charles M ...
-
Peto, Julian
-
Pharoah, Paul D. ...
-
Plaseska-Karanfi ...
-
Presneau, Nadege
-
Rack, Brigitte
-
Radice, Paolo
-
Ramachandran, Dh ...
-
Rashid, Muhammad ...
-
Rennert, Gad
-
Romero, Atocha
-
Ruddy, Kathryn J ...
-
Ruebner, Matthia ...
-
Saloustros, Emma ...
-
Sandler, Dale P.
-
Sawyer, Elinor J ...
-
Schmidt, Marjank ...
-
Schmutzler, Rita ...
-
Schneider, Micha ...
-
Scott, Christoph ...
-
Shah, Mitul
-
Sharma, Priyanka
-
Shen, Chen-Yang
-
Shu, Xiao-Ou
-
Simard, Jacques
-
Surowy, Harald
-
Tamimi, Rulla M.
-
Tapper, William ...
-
Taylor, Jack A.
-
Teo, Soo Hwang
-
Teras, Lauren R.
-
Toland, Amanda E ...
-
Tollenaar, Rob A ...
-
Torres, Diana
-
Torres-Mejia, Ga ...
-
Troester, Meliss ...
-
Truong, Therese
-
Vachon, Celine M ...
-
Vijai, Joseph
-
Weinberg, Claric ...
-
Wendt, Camilla
-
Winqvist, Robert
-
Wolk, Alicja
-
Wu, Anna H.
-
Yamaji, Taiki
-
Yang, Xiaohong R ...
-
Yu, Jyh-Cherng
-
Zheng, Wei
-
Ziogas, Argyrios
-
Ziv, Elad
-
Dunning, Alison ...
-
Easton, Douglas ...
-
Hemingway, Harry
-
Hamann, Ute
-
Kuchenbaecker, K ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Medical Genetics
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
Genome Medicine
- By the university
-
Uppsala University
-
Karolinska Institutet
-
Lund University