SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Group Invasion Working)
 

Sökning: WFRF:(Group Invasion Working) > Defining Morphologi...

  • Thunnissen, ErikUniv Amsterdam, Med Ctr, Amsterdam, Netherlands.;Univ Amsterdam, Med Ctr, Locat VUmc, Dept Pathol, Boelelaan 1117, NL-1081HV Amsterdam, Netherlands. (författare)

Defining Morphologic Features of Invasion in Pulmonary Nonmucinous Adenocarcinoma With Lepidic Growth : A Proposal by the International Association for the Study of Lung Cancer Pathology Committee

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • Elsevier,2023
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-501987
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501987URI
  • https://doi.org/10.1016/j.jtho.2022.11.026DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Introduction: Since the eight edition of the Union for In-ternational Cancer Control and American Joint Committee on Cancer TNM classification system, the primary tumor pT stage is determined on the basis of presence and size of the invasive components. The aim of this study was to identify histologic features in tumors with lepidic growth pattern which may be used to establish criteria for distinguishing invasive from noninvasive areas.Methods: A Delphi approach was used with two rounds of blinded anonymized analysis of resected nonmucinous lung adenocarcinoma cases with presumed invasive and nonin-vasive components, followed by one round of reviewer de-anonymized and unblinded review of cases with known outcomes. A digital pathology platform was used for measuring total tumor size and invasive tumor size. Results: The mean coefficient of variation for measuring total tumor size and tumor invasive size was 6.9% (range: 1.7%-22.3%) and 54% (range: 14.7%-155%), respectively, with substantial variations in interpretation of the size and location of invasion among pathologists. Following the presentation of the results and further discussion among members at large of the International Association for the Study of Lung Cancer Pathology Committee, extensive epithelial proliferation (EEP) in areas of collapsed lepidic growth pattern is recognized as a feature likely to be associated with invasive growth. The EEP is characterized by multilayered luminal epithelial cell growth, usually with high-grade cytologic features in several alveolar spaces.Conclusions: Collapsed alveoli and transition zones with EEP were identified by the Delphi process as morphologic features that were a source of interobserver variability. Definition criteria for collapse and EEP are proposed to improve reproducibility of invasion measurement.(c) 2022 International Association for the Study of Lung Cancer.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Beasley, Mary BethIcahn Sch Med Mt Sinai, Dept Pathol, New York, NY USA. (författare)
  • Borczuk, AlainNorthwell Hlth, Dept Pathol, Greenvale, NY USA. (författare)
  • Dacic, SanjaYale Sch Med, Dept Pathol, New Haven, CT USA. (författare)
  • Kerr, Keith M.Univ Aberdeen, Sch Med, Dept Pathol, Aberdeen, Scotland.;Aberdeen Royal Infirm, Aberdeen, Scotland. (författare)
  • Lissenberg-Witte, BirgitUniv Amsterdam, Amsterdam UMC Locat Vrije Univ, Dept Epidemiol & Data Sci, Med Ctr, Amsterdam, Netherlands. (författare)
  • Minami, YukoNatl Hosp Org Ibarakihigashi Natl Hosp, Ctr Chest Dis & Severe Motor & Intellectual Disabi, Dept Pathol, Tokai, Ibaraki, Japan. (författare)
  • Nicholson, Andrew G.Imperial Coll, Royal Brompton & Hare field Hosp, Guys & St ThomasNHS Fdn Trust, Dept Histopathol, London, England.;Imperial Coll, Natl Heart & Lung Inst, London, England. (författare)
  • Noguchi, MasayukiNarita Tomisato Tokushukai Hosp, Dept Pathol, Tsukuba, Japan.;Tokushukai East Pathol Ctr, Tsukuba, Japan. (författare)
  • Sholl, LynetteBrigham & Womens Hosp, Dept Pathol, Boston, MA USA. (författare)
  • Tsao, Ming-SoundUniv Hlth Network, Dept Pathol, Toronto, ON, Canada.;Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada. (författare)
  • Le Quesne, JohnUniv Glasgow, Beatson Canc Res Inst, NHS Greater Glasgow & Clyde Glasgow, Glasgow, Scotland. (författare)
  • Roden, Anja C.Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA. (författare)
  • Chung, Jin-HaengSeoul Natl Univ, Coll Med, Dept Pathol, Seoul, South Korea. (författare)
  • Yoshida, AkihikoNatl Canc Ctr, Dept Diagnost Pathol, Tokyo, Japan. (författare)
  • Moreira, Andre L.NYU Grossman Sch Med, Dept Pathol, New York, NY USA. (författare)
  • Lantuejoul, SylvieLeon Berard Canc Ctr, Dept Biopathol, Lyon, France.;INSERM, CRCL, U 1052, Lyon, France.;Grenoble Alpes Univ, Lyon, France. (författare)
  • Pelosi, GiuseppeUniv Milan, Dept Oncol & Hematooncol, Milan, Italy.;Ist Ricovero & Cura Carattere Sci IRCCS Multimed, Interhosp Pathol Div, Milan, Italy. (författare)
  • Poleri, ClaudiaOff Pathol Consultants, Buenos Aires, Argentina. (författare)
  • Hwang, DavidOdette Canc Ctr, Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada. (författare)
  • Jain, DeepaliAll India Inst Med Sci, Dept Pathol, New Delhi, India. (författare)
  • Travis, William D.Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY USA. (författare)
  • Brambilla, Elisabeth (författare)
  • Chen, GangFudan Univ, Hongshan Hosp, Shanghai, Peoples R China. (författare)
  • Botling, JohanUppsala universitet,Cancerprecisionsmedicin(Swepub:uu)johanbot (författare)
  • Bubendorf, LukasUniv Hosp Basel, Basel, Switzerland. (författare)
  • Mino-Kenudson, MariMassachusetts Gen Hosp, Dept Pathol, Boston, MA USA.;Harvard Med Sch, Boston, MA USA. (författare)
  • Motoi, NorikoSaitama Canc Ctr, Saitama, Japan. (författare)
  • Chou, Teh YingTaipei Vet Gen Hosp, Taipei, Taiwan. (författare)
  • Papotti, MauroUniv Turin, Dept Oncol, Turin, Italy. (författare)
  • Yatabe, YasushiNatl Canc Ctr, Dept Diagnost Pathol, Tokyo, Japan. (författare)
  • Cooper, WendyRoyal Prince Alfred Hosp, NSW Hlth Pathol, Camperdown, NSW, Australia. (författare)
  • Group, Invasion Working (författare)
  • Univ Amsterdam, Med Ctr, Amsterdam, Netherlands.;Univ Amsterdam, Med Ctr, Locat VUmc, Dept Pathol, Boelelaan 1117, NL-1081HV Amsterdam, Netherlands.Icahn Sch Med Mt Sinai, Dept Pathol, New York, NY USA. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Journal of Thoracic Oncology: Elsevier18:4, s. 447-4621556-08641556-1380

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy