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Emotion regulation ...
Emotion regulation and the salience network : a hypothetical integrative model of fibromyalgia
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- Pinto, Ana Margarida (författare)
- Univ Coimbra, Ctr Res Neuropsychol & Cognit & Behav Intervent C, Fac Psychol & Educ Sci, Coimbra, Portugal.;Univ Coimbra, Univ Clin Rheumatol, Fac Med, Coimbra, Portugal.;Univ Coimbra, Fac Med, Psychol Med Inst, Coimbra, Portugal.
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- Geenen, Rinie (författare)
- Univ Utrecht, Dept Psychol, Utrecht, Netherlands.;Altrecht Psychosomat Med Eikenboom, Zeist, Netherlands.
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- Wager, Tor D. (författare)
- Dartmouth Coll, Dept Psychol & Brain Sci, Hanover, NH 03755 USA.
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- Lumley, Mark A. (författare)
- Wayne State Univ, Dept Psychol, Detroit, MI USA.
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- Häuser, Winfried (författare)
- Tech Univ Munich, Dept Psychosomat Med & Psychotherapy, Munich, Germany.
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- Kosek, Eva (författare)
- Karolinska Institutet,Uppsala universitet,Klinisk smärtforskning,Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
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- Ablin, Jacob N. (författare)
- Tel Aviv Sourasky Med Ctr, Internal Med H, Tel Aviv, Israel.;Tel Aviv Univ, Sackler Sch Med, Ramat Aviv, Israel.
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- Amris, Kirstine (författare)
- Copenhagen Univ Hosp, Parker Inst, Dept Rheumatol, Bispebjerg, Denmark.;Copenhagen Univ Hosp, Parker Inst, Dept Rheumatol, Frederiksberg, Denmark.
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- Branco, Jaime (författare)
- Egas Moniz Hosp, Rheumatol Dept, Lisboa Ocidental Hosp Ctr CHLO EPE, Lisbon, Portugal.;NOVA Univ Lisbon NMS UNL, NOVA Med Sch, Chron Dis Res Ctr CEDOC, Comprehens Hlth Res Ctr CHRC, Lisbon, Portugal.
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- Buskila, Dan (författare)
- Ben Gurion Univ Negev Beer Sheba, Beer Sheva, Israel.
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- Castelhano, Joao (författare)
- Univ Coimbra, Coimbra Inst Biomed Imaging & Translat Res CIBIT, ICNAS, Coimbra, Portugal.
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- Castelo-Branco, Miguel (författare)
- Univ Coimbra, Coimbra Inst Biomed Imaging & Translat Res CIBIT, ICNAS, Coimbra, Portugal.
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- Crofford, Leslie J. (författare)
- Vanderbilt Univ, Dept Med, Div Rheumatol & Immunol, Med Ctr, Nashville, TN USA.
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- Fitzcharles, Mary-Ann (författare)
- McGill Univ, Dept Med, Div Rheumatol, Montreal, PQ, Canada.
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- Lopez-Sola, Marina (författare)
- Univ Barcelona, Dept Med & Hlth Sci, Serra Hunter Programme, Barcelona, Spain.
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- Luis, Mariana (författare)
- Coimbra Hosp & Univ Ctr, Rheumatol Dept, Coimbra, Portugal.
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- Marques, Tiago Reis (författare)
- Imperial Coll London, Hammersmith Hosp, MRC London Inst Med Sci LMS, Psychiat Imaging Grp, London, England.;Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychosis Studies, London, England.
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- Mease, Philip J. (författare)
- Providence St Joseph Hlth, Swedish Med Ctr, Seattle, WA USA.;Univ Washington, Sch Med, Seattle, WA USA.
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- Palavra, Filipe (författare)
- Coimbra Hosp & Univ Ctr, Paediat Hosp, Neuropediat Unit, Ctr Child Dev, Coimbra, Portugal.;Univ Coimbra, Fac Med, Coimbra Inst Clin & Biomed Res i CBR, Coimbra, Portugal.
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- Rhudy, Jamie L. (författare)
- Univ Tulsa, Dept Psychol, Tulsa, OK 74104 USA.
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- Uddin, Lucina Q. (författare)
- Univ Miami, Dept Psychol, POB 248185, Coral Gables, FL 33124 USA.
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- Castilho, Paula (författare)
- Univ Coimbra, Ctr Res Neuropsychol & Cognit & Behav Intervent C, Fac Psychol & Educ Sci, Coimbra, Portugal.
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- Jacobs, Johannes W. G. (författare)
- Univ Med Ctr Utrecht, Dept Rheumatol & Clin Immunol, Utrecht, Netherlands.
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- da Silva, Jose A. P. (författare)
- Univ Coimbra, Univ Clin Rheumatol, Fac Med, Coimbra, Portugal.;Coimbra Hosp & Univ Ctr, Rheumatol Dept, Coimbra, Portugal.;Univ Coimbra, Fac Med, Coimbra Inst Clin & Biomed Res i CBR, Coimbra, Portugal.
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Univ Coimbra, Ctr Res Neuropsychol & Cognit & Behav Intervent C, Fac Psychol & Educ Sci, Coimbra, Portugal;Univ Coimbra, Univ Clin Rheumatol, Fac Med, Coimbra, Portugal.;Univ Coimbra, Fac Med, Psychol Med Inst, Coimbra, Portugal. Univ Utrecht, Dept Psychol, Utrecht, Netherlands.;Altrecht Psychosomat Med Eikenboom, Zeist, Netherlands. (creator_code:org_t)
- 2022-12-05
- 2023
- Engelska.
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Ingår i: Nature Reviews Rheumatology. - : Springer Nature. - 1759-4790 .- 1759-4804. ; 19:1, s. 44-60
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other symptoms, and has a substantial socioeconomic impact. Current biomedical and psychosocial treatments are unsatisfactory for many patients, and treatment progress has been hindered by the lack of a clear understanding of the pathogenesis of fibromyalgia. We present here a model of fibromyalgia that integrates current psychosocial and neurophysiological observations. We propose that an imbalance in emotion regulation, reflected by an overactive 'threat' system and underactive 'soothing' system, might keep the 'salience network' (also known as the midcingulo-insular network) in continuous alert mode, and this hyperactivation, in conjunction with other mechanisms, contributes to fibromyalgia. This proposed integrative model, which we term the Fibromyalgia: Imbalance of Threat and Soothing Systems (FITSS) model, should be viewed as a working hypothesis with limited supporting evidence available. We hope, however, that this model will shed new light on existing psychosocial and biological observations, and inspire future research to address the many gaps in our knowledge about fibromyalgia, ultimately stimulating the development of novel therapeutic interventions.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
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Pinto, Ana Marga ...
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Geenen, Rinie
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Wager, Tor D.
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Lumley, Mark A.
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Häuser, Winfried
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Kosek, Eva
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visa fler...
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Ablin, Jacob N.
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Amris, Kirstine
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Branco, Jaime
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Buskila, Dan
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Castelhano, Joao
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Castelo-Branco, ...
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Crofford, Leslie ...
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Fitzcharles, Mar ...
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Lopez-Sola, Mari ...
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Luis, Mariana
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Marques, Tiago R ...
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Mease, Philip J.
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Palavra, Filipe
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Rhudy, Jamie L.
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Uddin, Lucina Q.
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Castilho, Paula
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Jacobs, Johannes ...
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da Silva, Jose A ...
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