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Chronic Airways Ass...
Chronic Airways Assessment Test : psychometric properties in patients with asthma and/or COPD
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- Tomaszewski, Erin L. (författare)
- AstraZeneca, BioPharmaceut Med, 1 Medimmune Way, Gaithersburg, MD 20878 USA.
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- Atkinson, Mark J. (författare)
- Evidera, Bethesda, MD USA.
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- Janson, Christer (författare)
- Uppsala universitet,Lung- allergi- och sömnforskning
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- Karlsson, Niklas (författare)
- AstraZeneca, BioPharmaceut Med, Gothenburg, Sweden.
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- Make, Barry (författare)
- Natl Jewish Hlth, Denver, CO USA.;Univ Colorado, Denver, CO USA.
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- Price, David (författare)
- Observat & Pragmat Res Inst, Singapore, Singapore.;Univ Aberdeen, Ctr Acad Primary Care, Div Appl Hlth Sci, Aberdeen, Scotland.
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- Reddel, Helen K. (författare)
- Univ Sydney, Woolcock Inst Med Res, Sydney, NSW, Australia.
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- Vogelmeier, Claus F. (författare)
- Univ Marburg, German Ctr Lung Res DZL, Dept Med Pulm & Crit Care Med, Marburg, Germany.
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- Müllerová, Hana (författare)
- AstraZeneca, BioPharmaceut Med, Cambridge, England.
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- Jones, Paul W. (författare)
- GlaxoSmithKline, Global Resp Franchise, Brentford, Middx, England.
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AstraZeneca, BioPharmaceut Med, 1 Medimmune Way, Gaithersburg, MD 20878 USA Evidera, Bethesda, MD USA. (creator_code:org_t)
- BioMed Central (BMC), 2023
- 2023
- Engelska.
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Ingår i: Respiratory Research. - : BioMed Central (BMC). - 1465-9921 .- 1465-993X. ; 24
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: No short patient-reported outcome (PRO) instruments assess overall health status across different obstructive lung diseases. Thus, the wording of the introduction to the Chronic Obstructive Pulmonary Disease (COPD) Assessment Test (CAT) was modified to permit use in asthma and/or COPD. This tool is called the Chronic Airways Assessment Test (CAAT).Methods: The psychometric properties of the CAAT were evaluated using baseline data from the NOVELTY study (NCT02760329) in patients with physician-assigned asthma, asthma + COPD or COPD. Analyses included exploratory/confirmatory factor analyses, differential item functioning and analysis of construct validity. Responses to the CAAT and CAT were compared in patients with asthma + COPD and those with COPD.Results: CAAT items were internally consistent (Cronbach's alpha: > 0.7) within each diagnostic group (n = 510). Models for structural and measurement invariance were strong. Tests of differential item functioning showed small differences between asthma and COPD in individual items, but these were not consistent in direction and had minimal overall impact on the total score. The CAAT and CAT were highly consistent when assessed in all NOVELTY patients who completed both (N = 277, Pearson's correlation coefficient: 0.90). Like the CAT itself, CAAT scores correlated moderately (0.4-0.7) to strongly (> 0.7) with other PRO measures and weakly (< 0.4) with spirometry measures.Conclusions: CAAT scores appear to reflect the same health impairment across asthma and COPD, making the CAAT an appropriate PRO instrument for patients with asthma and/or COPD. Its brevity makes it suitable for use in clinical studies and routine clinical practice.Trial registration: NCT02760329.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- Asthma
- COPD
- Patient-reported
- Psychometrics
- Chronic Airways Assessment Test
- COPD Assessment Test
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Tomaszewski, Eri ...
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Atkinson, Mark J ...
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Janson, Christer
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Karlsson, Niklas
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Make, Barry
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Price, David
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Reddel, Helen K.
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Vogelmeier, Clau ...
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Müllerová, Hana
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Jones, Paul W.
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