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Individual participant data meta-analysis to compare EPDS accuracy to detect major depression with and without the self-harm item

Qiu, Xia (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.;West China Second Univ Hosp, Sichuan Univ, Dept Pediat, Key Lab Obstetr & Gynecol & Pediat Dis & Birth De, Chengdu, Sichuan, Peoples R China.;McGill Univ, Dept Psychiat, Montreal, PQ, Canada.
Wu, Yin (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.;McGill Univ, Dept Psychiat, Montreal, PQ, Canada.
Sun, Ying (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
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Levis, Brooke (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.;Keele Univ, Sch Med, Ctr Prognosis Res, Keele, Staffs, England.;McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada.
Tian, Jizhou (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Boruff, Jill T. (author)
McGill Univ, Schulich Lib Phys Sci Life Sci & Engn, Montreal, PQ, Canada.
Cuijpers, Pim (author)
Vrije Univ, Dept Clin Neuro & Dev Psychol, Amsterdam, Netherlands.
Ioannidis, John P. A. (author)
Stanford Univ, Dept Epidemiol & Populat Hlth, Dept Biomed Data Sci, Dept Med, Stanford, CA USA.
Markham, Sarah (author)
Kings Coll London, Dept Biostat & Hlth Informat, London, England.
Ziegelstein, Roy C. (author)
Johns Hopkins Univ, Dept Med, Sch Med, Baltimore, MD USA.
Vigod, Simone N. (author)
Univ Toronto, Womens Coll Hosp & Res Inst, Toronto, ON, Canada.
Benedetti, Andrea (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.;McGill Univ, Dept Psychiat, Montreal, PQ, Canada.;McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada.;McGill Univ Hlth Ctr, Res Inst, Ctr Outcomes Res & Evaluat, Resp Epidemiol & Clin Res Unit, 5252 Blvd Maisonneuve, Montreal, PQ, Canada.;McGill Univ, Dept Med, Montreal, PQ, Canada.
Thombs, Brett (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.;McGill Univ, Dept Psychiat, Montreal, PQ, Canada.;McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada.;McGill Univ, Dept Med, Montreal, PQ, Canada.;McGill Univ, Dept Psychol, Montreal, PQ, Canada.;McGill Univ, Dept Educ & Counselling Psychol, Montreal, PQ, Canada.;McGill Univ, Biomed Eth Unit, Montreal, PQ, Canada.
He, Chen (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Krishnan, Ankur (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Bhandari, Parash Mani (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Neupane, Dipika (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Negeri, Zelalem (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Imran, Mahrukh (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Rice, Danielle B. (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Azar, Marleine (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Chiovitti, Matthew J. (author)
Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.
Gilbody, Simon A. (author)
Univ York, Hull York Med Sch, York, England.;Univ York, Dept Hlth Sci, York, England.
Kloda, Lorie B. (author)
Concordia Univ, Montreal, PQ, Canada.
Patten, Scott D. (author)
Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada.;Univ Calgary, Dept Psychiat, Calgary, AB, Canada.
Mitchell, Nicholas (author)
Univ Alberta, Dept Psychiat, Edmonton, AB, Canada.
Alvarado, Ruben (author)
Univ Chile, Sch Publ Hlth, Fac Med, Santiago, Chile.
Barnes, Jacqueline (author)
Univ London, Dept Psychol Sci, London, England.
Beck, Cheryl Tatano (author)
Univ Connecticut, Sch Nursing, Mansfield, CT USA.
Bindt, Carola (author)
Univ Med Ctr Hamburg Eppendorf, Dept Child & Adolescent Psychiat, Hamburg, Germany.
Correa, Humberto (author)
Univ Fed Minas Gerais, Fed Med, Belo Horizonte, MG, Brazil.
Castro e Couto, Tiago (author)
Univ Fed Uberlandia, Uberlandia, Brazil.
Chorwe-Sungani, Genesis (author)
Univ Malawi, Kamuzu Coll Nursing, Dept Mental Hlth, Blantyre, Malawi.
Eapen, Valsamma (author)
Univ New South Wales, Sch Psychiat, Kensington, Australia.
Favez, Nicolas (author)
Univ Geneva, Fac Psychol & Educ Sci, Geneva, Switzerland.
Felice, Ethel (author)
Mt Carmel Hosp, Dept Psychiat, Attard, Malta.
Fellmeth, Gracia (author)
Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England.
Fernandes, Michelle (author)
Univ Southampton, MRC Lifecourse Epidemiol Ctr, Dept Paediat, Southampton, England.;Univ Southampton, Fac Med, Southampton, England.
Field, Sally (author)
Univ Cape Town, Dept Psychiat & Mental Hlth, Alan J Flisher Ctr Publ Mental Hlth, Perinatal Mental Hlth Project, Cape Town, South Africa.
Figueiredo, Barbara (author)
Univ Minho, Sch Psychol, Braga, Portugal.
Fisher, Jane R. W. (author)
Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Australia.
Green, Eric P. (author)
Duke Global Hlth Inst, Durham, NC USA.
Honikman, Simone (author)
Univ Cape Town, Dept Psychiat & Mental Hlth, Alan J Flisher Ctr Publ Mental Hlth, Perinatal Mental Hlth Project, Cape Town, South Africa.
Howard, Louise M. (author)
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England.
Kettunen, Pirjo A. (author)
North Karelia Cent Hosp, Dept Gen Hosp Psychiat, Joensuu, Finland.
Kohlhoff, Jane (author)
Univ New South Wales, Sch Psychiat, Kensington, Australia.
Kozinszky, Zoltan (author)
Danderyd Hosp, Dept Obstet & Gynecol, Stockholm, Sweden.
Leonardou, Angeliki A. (author)
Athens Univ, Dept Psychiat, Womens Mental Hlth Clin, Med Sch, Athens, Greece.
Maes, Michael (author)
Chulalongkorn Univ, Dept Psychiat, Fac Med, Bangkok, Thailand.
Martinez, Pablo (author)
Univ Santiago de Chile, Fac Humanidades, Escuela Psicol, Santiago, Chile.
Rados, Sandra Nakic (author)
Catholic Univ Croatia, Dept Psychol, Zagreb, Croatia.
Nishi, Daisuke (author)
Univ Tokyo, Grad Sch Med, Dept Mental Hlth, Tokyo, Japan.
Pawlby, Susan J. (author)
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England.
Rochat, Tamsen J. (author)
Univ Witwatersrand, MRC Dev Pathways Hlth Res Unit, Fac Hlth Sci, Johannesburg, South Africa.
Rowe, Heather J. (author)
Sharp, Deborah J. (author)
Univ Bristol, Ctr Acad Primary Care, Bristol Med Sch, Bristol, England.
Skalkidou, Alkistis, 1977- (author)
Uppsala universitet,Obstetrisk och reproduktiv hälsoforskning
Smith-Nielsen, Johanne (author)
Univ Copenhagen, Ctr Early Intervent & Family Studies, Dept Psychol, Copenhagen, Denmark.
Stein, Alan (author)
Univ Oxford, Dept Psychiat, Oxford, England.
Su, Kuan-Pin (author)
China Med Univ, China Med Univ Hosp, An Nan Hosp, Taichung, Taiwan.;China Med Univ, Mind Body Interface Lab, Taichung, Taiwan.
Sundström Poromaa, Inger, 1964- (author)
Uppsala universitet,Reproduktiv hälsa
Tadinac, Meri (author)
Univ Zagreb, Dept Psychol, Fac Human & Social Sci, Zagreb, Croatia.
Tandon, S. Darius (author)
Northwestern Univ, Sch Med, Chicago, IL USA.
Tendais, Iva (author)
Univ Minho, Sch Psychol, Braga, Portugal.
Toereki, Annamaria D. (author)
Univ Szeged, Dept Emergency, Szeged, Hungary.
Tran, Thach (author)
Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Australia.
Trevillion, Kylee (author)
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England.
Turner, Katherine S. (author)
San Paolo Hosp, Epilepsy Ctr Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, Milan, Italy.
Vaever, Mette (author)
Univ Copenhagen, Ctr Early Intervent & Family Studies, Dept Psychol, Copenhagen, Denmark.
van Heyningen, Thandi M. (author)
Univ Cape Town, Dept Psychiat & Mental Hlth, Alan J Flisher Ctr Publ Mental Hlth, Perinatal Mental Hlth Project, Cape Town, South Africa.
Vega-Dienstmaier, Johann (author)
Univ Peruana Cayetano Heredia, Fac Med Alberto Hurtado, Lima, Peru.
Wynter, Karen A. (author)
Deakin Univ, Sch Nursing & Midwifery, Melbourne, Australia.
Yonkers, Kimberly (author)
Yale Sch Med, Dept Psychiat, New Haven, CT USA.
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Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada;West China Second Univ Hosp, Sichuan Univ, Dept Pediat, Key Lab Obstetr & Gynecol & Pediat Dis & Birth De, Chengdu, Sichuan, Peoples R China.;McGill Univ, Dept Psychiat, Montreal, PQ, Canada. Jewish Gen Hosp, Lady Davis Inst Med Res, 4333 Cote Ste Catherine Rd, Montreal, PQ, Canada.;McGill Univ, Dept Psychiat, Montreal, PQ, Canada. (creator_code:org_t)
2023-03-10
2023
English.
In: Scientific Reports. - : Springer Nature. - 2045-2322. ; 13
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Item 10 of the Edinburgh Postnatal Depression Scale (EPDS) is intended to assess thoughts of intentional self-harm but may also elicit concerns about accidental self-harm. It does not specifically address suicide ideation but, nonetheless, is sometimes used as an indicator of suicidality. The 9-item version of the EPDS (EPDS-9), which omits item 10, is sometimes used in research due to concern about positive endorsements of item 10 and necessary follow-up. We assessed the equivalence of total score correlations and screening accuracy to detect major depression using the EPDS-9 versus full EPDS among pregnant and postpartum women. We searched Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, and Web of Science from database inception to October 3, 2018 for studies that administered the EPDS and conducted diagnostic classification for major depression based on a validated semi-structured or fully structured interview among women aged 18 or older during pregnancy or within 12 months of giving birth. We conducted an individual participant data meta-analysis. We calculated Pearson correlations with 95% prediction interval (PI) between EPDS-9 and full EPDS total scores using a random effects model. Bivariate random-effects models were fitted to assess screening accuracy. Equivalence tests were done by comparing the confidence intervals (CIs) around the pooled sensitivity and specificity differences to the equivalence margin of delta = 0.05. Individual participant data were obtained from 41 eligible studies (10,906 participants, 1407 major depression cases). The correlation between EPDS-9 and full EPDS scores was 0.998 (95% PI 0.991, 0.999). For sensitivity, the EPDS-9 and full EPDS were equivalent for cut-offs 7-12 (difference range - 0.02, 0.01) and the equivalence was indeterminate for cut-offs 13-15 (all differences - 0.04). For specificity, the EPDS-9 and full EPDS were equivalent for all cut-offs (difference range 0.00, 0.01). The EPDS-9 performs similarly to the full EPDS and can be used when there are concerns about the implications of administering EPDS item 10.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

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Qiu, Xia
Wu, Yin
Sun, Ying
Levis, Brooke
Tian, Jizhou
Boruff, Jill T.
show more...
Cuijpers, Pim
Ioannidis, John ...
Markham, Sarah
Ziegelstein, Roy ...
Vigod, Simone N.
Benedetti, Andre ...
Thombs, Brett
He, Chen
Krishnan, Ankur
Bhandari, Parash ...
Neupane, Dipika
Negeri, Zelalem
Imran, Mahrukh
Rice, Danielle B ...
Azar, Marleine
Chiovitti, Matth ...
Gilbody, Simon A ...
Kloda, Lorie B.
Patten, Scott D.
Mitchell, Nichol ...
Alvarado, Ruben
Barnes, Jacqueli ...
Beck, Cheryl Tat ...
Bindt, Carola
Correa, Humberto
Castro e Couto, ...
Chorwe-Sungani, ...
Eapen, Valsamma
Favez, Nicolas
Felice, Ethel
Fellmeth, Gracia
Fernandes, Miche ...
Field, Sally
Figueiredo, Barb ...
Fisher, Jane R. ...
Green, Eric P.
Honikman, Simone
Howard, Louise M ...
Kettunen, Pirjo ...
Kohlhoff, Jane
Kozinszky, Zolta ...
Leonardou, Angel ...
Maes, Michael
Martinez, Pablo
Rados, Sandra Na ...
Nishi, Daisuke
Pawlby, Susan J.
Rochat, Tamsen J ...
Rowe, Heather J.
Sharp, Deborah J ...
Skalkidou, Alkis ...
Smith-Nielsen, J ...
Stein, Alan
Su, Kuan-Pin
Sundström Poroma ...
Tadinac, Meri
Tandon, S. Dariu ...
Tendais, Iva
Toereki, Annamar ...
Tran, Thach
Trevillion, Kyle ...
Turner, Katherin ...
Vaever, Mette
van Heyningen, T ...
Vega-Dienstmaier ...
Wynter, Karen A.
Yonkers, Kimberl ...
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