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Evidenced-Based App...
Evidenced-Based Approaches to Support the Development of Endocrine-Mediated Adverse Outcome Pathways : Challenges and Opportunities
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- Audouze, Karine (author)
- Univ Paris, T3S, Inserm U1124, Paris, France.,Université de Paris, T3S, Inserm U1124, Paris, France
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- Zgheib, Elias (author)
- Univ Paris, T3S, Inserm U1124, Paris, France.,Université de Paris, T3S, Inserm U1124, Paris, France
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- Abass, Khaled (author)
- Univ Oulu, Univ Arctic, Thule Inst, Oulu, Finland.;Menoufia Univ, Dept Pesticides, Menoufia, Egypt.,Thule Institute, University of Arctic, University of Oulu, Oulu, Finland; Department of Pesticides, Menoufia University, Menoufia, Egypt
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- Baig, Asma H. (author)
- Brunel Univ London, Ctr Pollut Res & Policy, Uxbridge, England.,Centre for Pollution Research and Policy, Brunel University London, Uxbridge, United Kingdom,Department of Biology, University of Southern Denmark, Odense, Denmark,Univ Southern Denmark, Dept Biol, Odense, Denmark.
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- Forner-Piquer, Isabel (author)
- Brunel Univ London, Ctr Pollut Res & Policy, Uxbridge, England.,Centre for Pollution Research and Policy, Brunel University London, Uxbridge, United Kingdom
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- Holbech, Henrik (author)
- Univ Southern Denmark, Dept Biol, Odense, Denmark.
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- Knapen, Dries (author)
- Univ Antwerp, Dept Vet Sci, Zebrafishlab, Antwerp, Belgium.,Zebrafishlab, Department of Veterinary Sciences, University of Antwerp, Wilrijk, Belgium
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- Leonards, Pim E. G. (author)
- Vrije Univ Amsterdam, Dept Environm & Hlth, Amsterdam, Netherlands.,Department of Environment and Health, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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- Lupu, Diana I. (author)
- Uppsala universitet,Fysiologi och miljötoxikologi,Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
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- Palaniswamy, Saranya (author)
- Univ Oulu, Fac Med, Ctr Life Course Hlth Res, Oulu, Finland.,Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland
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- Rautio, Arja (author)
- Univ Oulu, Univ Arctic, Thule Inst, Oulu, Finland.,Thule Institute, University of Arctic, University of Oulu, Oulu, Finland
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- Sapounidou, Maria (author)
- Umeå universitet,Kemiska institutionen,Umeå Univ, Fac Sci & Technol, Dept Chem, Umeå, Sweden.
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- Martin, Olwenn V. (author)
- Brunel Univ London, Ctr Pollut Res & Policy, Uxbridge, England.,Centre for Pollution Research and Policy, Brunel University London, Uxbridge, United Kingdom
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Univ Paris, T3S, Inserm U1124, Paris, France Université de Paris, T3S, Inserm U1124, Paris, France (creator_code:org_t)
- 2021-12-21
- 2021
- English.
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In: Frontiers in Toxicology. - : Frontiers Media S.A.. - 2673-3080. ; 3
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Abstract
Subject headings
Close
- A transformation of regulatory toxicology is underway to meet the demands of testing increasing numbers of chemicals whilst reducing reliance on in vivo models. This transformation requires a shift from chemical safety assessment largely based on direct empirical observation of apical toxicity outcomes in whole organisms to predictive approaches in which outcomes and risks are inferred from accumulated mechanistic understanding.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Keyword
- adverse outcome pathways
- endocrine disruption
- systematic (literature) review
- machine learning
- evidence-based methods
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Audouze, Karine
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Zgheib, Elias
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Abass, Khaled
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Baig, Asma H.
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Forner-Piquer, I ...
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Holbech, Henrik
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show more...
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Knapen, Dries
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Leonards, Pim E. ...
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Lupu, Diana I.
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Palaniswamy, Sar ...
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Rautio, Arja
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Sapounidou, Mari ...
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Martin, Olwenn V ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Pharmacology and ...
- Articles in the publication
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Frontiers in Tox ...
- By the university
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Uppsala University
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Umeå University