(WFRF:(Claeson Per))
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- Broussalis, Adriana M. (author)
First cyclotide from Hybanthus (Violaceae)
- Article/chapterEnglish2001
Publisher, publication year, extent ...
- Elsevier,2001
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-51280
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-51280URI
- https://doi.org/10.1016/S0031-9422(01)00173-XDOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-89793URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Hypa A, a novel macrocyclic polypeptide containing 30 amino acid residues, has been isolated from the n-butanol extract of the Argentine plant Hybanthus parviflorus. The sequence, cyclo-(SCVYIPCTITALLGCSCKNKVCYNGIPCAE), was determined by automated Edman degradation, quantitative amino acid analysis and nanospray MS/MS2. Three intramolecular disulfide bridges stabilize the cyclic peptide backbone of hypa A. Using these structural features to classify the peptide as a cyclotide, we extended the distribution of that substance class to a new genus, and now propose a uniform nomenclature for cyclotides.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Farmaceutiska vetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Pharmaceutical Sciences hsv//eng
- Hybanthus parviflorus (Mutis ex L. F.) Baill.; Violaceae; Violetilla; Isolation; Primary structure; Cyclotides; Macrocyclic polypeptides; Hypa A; LCQ
- Pharmacognosy
- Farmakognosi
Added entries (persons, corporate bodies, meetings, titles ...)
- Göransson, UlfUppsala universitet,Avdelningen för farmakognosi(Swepub:uu)ugo29049 (author)
- Coussio, Jorge D. (author)
- Ferraro, Graciela (author)
- Martino, Virginia (author)
- Claeson, PerUppsala universitet,Avdelningen för farmakognosi(Swepub:uu)perclaes (author)
- Uppsala universitetAvdelningen för farmakognosi (creator_code:org_t)
Related titles
- In:Phytochemistry: Elsevier58:1, s. 47-510031-94221873-3700
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- Uppsala University
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