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Hexavalent chromium...
Hexavalent chromium still a concern in Sweden : Evidence from a cross-sectional study within the SafeChrom project
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- Jiang, Zheshun (författare)
- Lund University,Lunds universitet,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Genetic Occupational and Environmental Medicine,Lund University Research Groups,Lund Univ, Sweden
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- Schenk, Linda (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden
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- Assarsson, Eva (författare)
- Lund University,Lunds universitet,Metalund,Annan verksamhet, LTH,Lunds Tekniska Högskola,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Other operations, LTH,Faculty of Engineering, LTH,Genetic Occupational and Environmental Medicine,Lund University Research Groups,Lund Univ, Sweden
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- Albin, Maria (författare)
- Karolinska Institute,Lund University,Lunds universitet,Karolinska Institutet,Miljöepidemiologi,Forskargrupper vid Lunds universitet,Environmental Epidemiology,Lund University Research Groups,Metalund,Annan verksamhet, LTH,Lunds Tekniska Högskola,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Genetisk arbets- och miljömedicin,Other operations, LTH,Faculty of Engineering, LTH,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Genetic Occupational and Environmental Medicine,Region Skåne,Lund Univ, Sweden; Karolinska Inst, Sweden,Lund Univ, Sweden; Occupat & Environm Med, Sweden
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- Bertilsson, Helen (författare)
- Umeå University,Umeå universitet,Avdelningen för hållbar hälsa,Umea Univ, Sweden
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- Dock, Eva (författare)
- Lund University,Lunds universitet,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Genetic Occupational and Environmental Medicine,Lund University Research Groups,Region Skåne,Lund Univ, Sweden; Occupat & Environm Med, Sweden
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- Hagberg, Jessika, 1974- (författare)
- Örebro University,Örebro universitet,Institutionen för naturvetenskap och teknik,Department of Occupational and Environmental Health, Faculty of Business, Science and Engineering, Örebro University, Örebro, Sweden,Orebro Univ, Sweden
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- Karlsson, Lovisa E. (författare)
- Department of Occupational and Environmental Medicine, Örebro University Hospital, Region Örebro County, Sweden,Orebro Univ Hosp, Sweden
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- Kines, Pete (författare)
- National Research Centre for the Working Environment, Copenhagen, Denmark,Natl Res Ctr Working Environm, Denmark
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- Krais, Annette M (författare)
- Lund University,Lunds universitet,Tillämpad masspektrometri inom miljömedicin,Forskargrupper vid Lunds universitet,Centrum för hälsosamma inomhusmiljöer, CHIE,Annan verksamhet, LTH,Lunds Tekniska Högskola,LTH profilområde: Aerosoler,LTH profilområden,Applied Mass Spectrometry in Environmental Medicine,Lund University Research Groups,Centre for Healthy Indoor Environments,Other operations, LTH,Faculty of Engineering, LTH,LTH Profile Area: Aerosols,LTH Profile areas,Faculty of Engineering, LTH,Lund Univ, Sweden
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- Ljunggren, Stefan (författare)
- Linköpings universitet,Linköping University,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Arbets- och miljömedicin
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- Lundh, Thomas (författare)
- Lund University,Lunds universitet,Metalund,Annan verksamhet, LTH,Lunds Tekniska Högskola,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Other operations, LTH,Faculty of Engineering, LTH,Genetic Occupational and Environmental Medicine,Lund University Research Groups,Lund Univ, Sweden
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- Modig, Lars (författare)
- Umeå University,Umeå universitet,Avdelningen för hållbar hälsa,Umea Univ, Sweden
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- Möller, Rickie (författare)
- Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Sweden
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- Pineda, Daniela (författare)
- Lund University,Lunds universitet,Metalund,Annan verksamhet, LTH,Lunds Tekniska Högskola,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Tillämpad masspektrometri inom miljömedicin,Other operations, LTH,Faculty of Engineering, LTH,Genetic Occupational and Environmental Medicine,Lund University Research Groups,Applied Mass Spectrometry in Environmental Medicine,Lund Univ, Sweden
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- Ricklund, Niklas, 1979- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Occupational and Environmental Medicine, Örebro University Hospital, Region Örebro County, Sweden,Orebro Univ Hosp, Sweden
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- Saber, Anne T. (författare)
- National Research Centre for the Working Environment, Copenhagen, Denmark,Natl Res Ctr Working Environm, Denmark
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- Storsjö, Tobias (författare)
- Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Sweden
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- Taher Amir, Evana (författare)
- Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden,Stockholm Regional Council,Ctr Occupat & Environm Med, Sweden
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- Tinnerberg, Håkan (författare)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Lund University,Lunds universitet,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Genetic Occupational and Environmental Medicine,Lund University Research Groups,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Tondel, Martin (författare)
- Uppsala universitet,Arbets- och miljömedicin,Occupational and Environmental Medicine, Department of Medical Sciences, Uppsala University, Uppsala, Sweden; Occupational and Environmental Medicine, Uppsala University Hospital, Uppsala, Sweden,Uppsala Univ, Sweden; Uppsala Univ Hosp, Sweden
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- Vogel, Ulla (författare)
- National Research Centre for the Working Environment, Copenhagen, Denmark,Natl Res Ctr Working Environm, Denmark
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- Wiebert, Pernilla (författare)
- Karolinska Institute,Karolinska Institutet,Stockholm Regional Council,Karolinska Inst, Sweden; Ctr Occupat & Environm Med, Sweden
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- Broberg, Karin (författare)
- Karolinska Institute,Lund University,Lunds universitet,Karolinska Institutet,Metalund,Annan verksamhet, LTH,Lunds Tekniska Högskola,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,LTH profilområde: Aerosoler,LTH profilområden,Other operations, LTH,Faculty of Engineering, LTH,Genetic Occupational and Environmental Medicine,Lund University Research Groups,LTH Profile Area: Aerosols,LTH Profile areas,Faculty of Engineering, LTH,Lund Univ, Sweden; Karolinska Inst, Sweden; Natl Res Ctr Working Environm, Denmark; Lund Univ, Sweden
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Engfeldt, Malin (författare)
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(creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: International journal of hygiene and environmental health. - : Elsevier. - 1438-4639 .- 1618-131X. ; 256
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://umu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- ObjectivesHexavalent chromium (Cr(VI)) is classified as a human carcinogen. Occupational Cr(VI) exposure can occur during different work processes, but the current exposure to Cr(VI) at Swedish workplaces is unknown.MethodsThis cross-sectional study (SafeChrom) recruited non-smoking men and women from 14 companies with potential Cr(VI) exposure (n = 113) and controls from 6 companies without Cr(VI) exposure (n = 72). Inhalable Cr(VI) was measured by personal air sampling (outside of respiratory protection) in exposed workers. Total Cr was measured in urine (pre- and post-shift, density-adjusted) and red blood cells (RBC) (reflecting Cr(VI)) in exposed workers and controls. The Bayesian tool Expostats was used to assess risk and evaluate occupational exposure limit (OEL) compliance.ResultsThe exposed workers performed processing of metal products, steel production, welding, plating, and various chemical processes. The geometric mean concentration of inhalable Cr(VI) in exposed workers was 0.15 μg/m3 (95% confidence interval: 0.11–0.21). Eight of the 113 exposed workers (7%) exceeded the Swedish OEL of 5 μg/m3, and the Bayesian analysis estimated the share of OEL exceedances up to 19.6% for stainless steel welders. Median post-shift urinary (0.60 μg/L, 5th-95th percentile 0.10–3.20) and RBC concentrations (0.73 μg/L, 0.51–2.33) of Cr were significantly higher in the exposed group compared with the controls (urinary 0.10 μg/L, 0.06–0.56 and RBC 0.53 μg/L, 0.42–0.72). Inhalable Cr(VI) correlated with urinary Cr (rS = 0.64) and RBC-Cr (rS = 0.53). Workers within steel production showed the highest concentrations of inhalable, urinary and RBC Cr. Workers with inferred non-acceptable local exhaustion ventilation showed significantly higher inhalable Cr(VI), urinary and RBC Cr concentrations compared with those with inferred acceptable ventilation. Furthermore, workers with inferred correct use of respiratory protection were exposed to significantly higher concentrations of Cr(VI) in air and had higher levels of Cr in urine and RBC than those assessed with incorrect or no use. Based on the Swedish job-exposure-matrix, approximately 17 900 workers were estimated to be occupationally exposed to Cr(VI) today.ConclusionsOur study demonstrates that some workers in Sweden are exposed to high levels of the non-threshold carcinogen Cr(VI). Employers and workers seem aware of Cr(VI) exposure, but more efficient exposure control strategies are required. National strategies aligned with the European strategies are needed in order to eliminate this cause of occupational cancer.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Hexavalent chromium
- Occupational cancer
- Inhalable
- Biomonitoring
- Occupational exposure limits
- Arbets- och miljömedicin
- Occupational and Environmental Medicine
- Hexavalent chromium
- Occupational cancer
- Inhalable
- Biomonitoring
- Occupational exposure limits
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Jiang, Zheshun
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Schenk, Linda
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Assarsson, Eva
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Albin, Maria
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Bertilsson, Hele ...
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Dock, Eva
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visa fler...
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Hagberg, Jessika ...
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Karlsson, Lovisa ...
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Kines, Pete
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Krais, Annette M
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Ljunggren, Stefa ...
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Lundh, Thomas
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Modig, Lars
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Möller, Rickie
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Pineda, Daniela
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Ricklund, Niklas ...
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Saber, Anne T.
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Storsjö, Tobias
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Taher Amir, Evan ...
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Tinnerberg, Håka ...
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Tondel, Martin
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Vogel, Ulla
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Wiebert, Pernill ...
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Broberg, Karin
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Engfeldt, Malin
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Uppsala universitet
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Örebro universitet
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Umeå universitet
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Karolinska Institutet
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Lunds universitet
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Linköpings universitet
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Göteborgs universitet
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