Nordic anal cancer (NOAC) group consensus guidelines for risk-adapted delineation of the elective clinical target volume in anal cancer

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Nordic anal cancer (NOAC) group consensus guidelines for risk-adapted delineation of the elective clinical target volume in anal cancer

Nilsson, Martin P. (författare): Lund University,Lunds universitet,Lund Univ, Dept Clin Sci, Div Oncol & Pathol, Lund, Sweden.;Skane Univ Hosp, Dept Hematol Oncol & Radiat Phys, Lund, Sweden.,Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Systemisk strålterapi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Systemic radiation therapy,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine

Undseth, Christine (författare): Oslo Univ Hosp, Dept Oncol, Oslo, Norway.,Department of Oncology, Oslo University Hospital, Oslo, Norway

Albertsson, Per (författare): Sahlgrens Univ Hosp, Dept Oncol, Gothenburg, Region Vastra G, Sweden.;Univ Gothenburg, Inst Clin Sci, Sahlgrenska Acad, Dept Oncol, Gothenburg, Sweden.,Sahlgrenska University Hospital, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Region Västra Götaland, Gothenburg, Sweden

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Eidem, Monika (författare): Trondheim Reg & Univ Hosp, St Olavs Hosp, Canc Clin, Trondheim, Norway.,Cancer Clinic, St. Olavs Hospital, Trondheim University Hospital, Norway

Havelund, Birgitte Mayland (författare): Lillebaelt Hosp, Univ Hosp Southern Denmark, Dept Oncol, Vejle, Denmark.,Department of Oncology, University Hospital of Southern Denmark, Lillebaelt Hospital, Vejle, Denmark

Johannsson, Jakob (författare): Landspitali Univ Hosp, Dept Radiat Oncol, Reykjavik, Iceland.,Department of Radiation Oncology, Landspitali University Hospital, Reykjavik, Iceland,National University Hospital of Iceland

Johnsson, Anders (författare): Lund University,Lunds universitet,Terapeutisk patologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Therapeutic pathology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital

Radu, Calin, 1969- (författare): Uppsala University,Uppsala universitet,Cancerprecisionsmedicin,Department of Immunology, Genetics and Pathology, Uppsala University, Sweden

Serup-Hansen, Eva (författare): Copenhagen Univ Hosp Herlev & Gentofte, Dept Oncol, Copenhagen, Denmark.,Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark

Spindler, Karen-Lise (författare): Aarhus Univ Hosp, Dept Oncol, Aarhus, Denmark.,Department of Oncology, Aarhus University Hospital, Aarhus, Denmark

Zackrisson, Björn (författare): Umeå University,Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci Oncol, Umeå, Sweden.

Guren, Marianne G. (författare): Oslo Univ Hosp, Dept Oncol, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.,Department of Oncology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway

Kronborg, Camilla (författare): Aarhus Univ Hosp, Ctr Particle Therapy, Danish, Aarhus, Denmark.;Aarhus Univ, Dept Clin Med, Aarhus, Denmark.,Centre for Particle Therapy, Aarhus University Hospital, Denmark. Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

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Lund Univ, Dept Clin Sci, Div Oncol & Pathol, Lund, Sweden;Skane Univ Hosp, Dept Hematol Oncol & Radiat Phys, Lund, Sweden. Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden (creator_code:org_t)

Taylor & Francis, 2023
2023
Engelska.
Ingår i: Acta Oncologica. - : Taylor & Francis. - 0284-186X .- 1651-226X. ; 62:8, s. 897-906

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Tidskriftsartikel (refereegranskat)

Abstract Ämnesord

Stäng

Background: To date, anal cancer patients are treated with radiotherapy to similar volumes despite a marked difference in risk profile based on tumor location and stage. A more individualized approach to delineation of the elective clinical target volume (CTVe) could potentially provide better oncological outcomes as well as improved quality of life. The aim of the present work was to establish Nordic Anal Cancer (NOAC) group guidelines for delineation of the CTVe in anal cancer.Methods: First, 12 radiation oncologists reviewed the literature in one of the following four areas: (1) previous delineation guidelines; (2) patterns of recurrence; (3) anatomical studies; (4) common iliac and para-aortic recurrences and delineation guidelines. Second, areas of controversy were identified and discussed with the aim of reaching consensus.Results: We present consensus-based recommendations for CTVe delineation in anal cancer regarding (a) which regions to include, and (b) how the regions should be delineated. Some of our recommendations deviate from current international guidelines. For instance, the posterolateral part of the inguinal region is excluded, decreasing the volume of irradiated normal tissue. For the external iliac region and the cranial border of the CTVe, we agreed on specifying two different recommendations, both considered acceptable. One of these recommendations is novel and risk-adapted; the external iliac region is omitted for low-risk patients, and several different cranial borders are used depending on the individual level of risk.Conclusion: We present NOAC consensus guidelines for delineation of the CTVe in anal cancer, including a risk-adapted strategy.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Anal carcinoma
delineation
contouring
para-aortic
common iliac
>
Anal carcinoma
common iliac
contouring
delineation
para-aortic

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Av författaren/redakt...: Nilsson, Martin ...; Undseth, Christi ...; Albertsson, Per; Eidem, Monika; Havelund, Birgit ...; Johannsson, Jako ...; visa fler...; Johnsson, Anders; Radu, Calin, 196 ...; Serup-Hansen, Ev ...; Spindler, Karen- ...; Zackrisson, Björ ...; Guren, Marianne ...; Kronborg, Camill ...; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Cancer och onkol ...

Artiklar i publikationen: Acta Oncologica

Av lärosätet: Uppsala universitet; Umeå universitet; Lunds universitet

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