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Early mobilisation ...
Early mobilisation in critically ill COVID-19 patients : a subanalysis of the ESICM-initiated UNITE-COVID observational study
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- Kloss, Philipp (författare)
- Charite Univ Med Berlin, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Dept Anesthesiol & Intens Care Med CCM CVK, Berlin, Germany.
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- Lindholz, Maximilian (författare)
- Charite Univ Med Berlin, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Dept Anesthesiol & Intens Care Med CCM CVK, Berlin, Germany.
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- Milnik, Annette (författare)
- Univ Basel, Dept Biomed, Res Platform Mol & Cognit Neurosci MCN, Basel, Switzerland.
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- Azoulay, Elie (författare)
- Paris Univ, St Louis Hosp, APHP, Med Intens & Reanimat, Paris, France.;Univ Paris, Paris, France.
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- Cecconi, Maurizio (författare)
- Humanitas Univ, Dept Biomed Sci, Via Rita Levi Montalcini 4, I-20072 Pieve Emanuele, Milan, Italy.;IRCCS Humanitas Res Hosp, Via Manzoni 56, I-20089 Milan, Rozzano, Italy.
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- Citerio, Giuseppe (författare)
- Univ Milano Bicocca, Sch Med & Surg, Milan, Italy.;IRCCS Fdn San Gerardo dei Tintori, Dept Neurosci Neurointens Care, Monza, Italy.
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- De Corte, Thomas (författare)
- Univ Ghent, Fac Med & Hlth Sci, Dept Internal Med & Pediat, Ghent, Belgium.;Ghent Univ Hosp, Dept Intens Care Med, Ghent, Belgium.
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- Duska, Frantisek (författare)
- Charles Univ Prague, Fac Med 3, Dept Anaesthesia & Intens Care, Prague, Czech Republic.;FNKV Univ Hosp Prague, Prague, Czech Republic.
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- Galarza, Laura (författare)
- Hosp Gen Univ Castellon, Intens Care Unit, Castellon de La Plana, Spain.
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- Greco, Massimiliano (författare)
- Humanitas Univ, Dept Biomed Sci, Via Rita Levi Montalcini 4, I-20072 Pieve Emanuele, Milan, Italy.;IRCCS Humanitas Res Hosp, Via Manzoni 56, I-20089 Milan, Rozzano, Italy.
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- Girbes, Armand R. J. (författare)
- Vrije Univ Amsterdam, Locat VUmc,Res VUmc Intens Care REVIVE, UMC,Amsterdam Cardiovasc Sci ACS,Amsterdam Med, Amsterdam Infect & Immun Inst AI&II,Dept Intens C, Amsterdam, Netherlands.
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- Kesecioglu, Jozef (författare)
- Univ Utrecht, Univ Med Ctr Utrecht, Dept Intens Care Med, Utrecht, Netherlands.
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- Mellinghoff, Johannes (författare)
- Univ Brighton, Sch Sports & Hlth Sci, Brighton, E Sussex, England.
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- Ostermann, Marlies (författare)
- Kings Coll London, Guys & St Thomas Hosp, Dept Crit Care, London, England.
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- Pellegrini, Mariangela (författare)
- Uppsala universitet,Hedenstiernalaboratoriet,Akad Sjukhuset, AnOpIVA, Intens Care Unit, Uppsala, Sweden.
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- Teboul, Jean-Louis (författare)
- Univ Paris Saclay, Hop Bicetre, APHP, Serv Med Intens Reanimat,Inserm UMR S 999, Le Kremlin Bicetre, France.
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- De Waele, Jan (författare)
- Univ Ghent, Fac Med & Hlth Sci, Dept Internal Med & Pediat, Ghent, Belgium.;Ghent Univ Hosp, Dept Intens Care Med, Ghent, Belgium.
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- Wong, Adrian (författare)
- Kings Coll Hosp London, Dept Crit Care, London, England.
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- Schaller, Stefan J. (författare)
- Charite Univ Med Berlin, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Dept Anesthesiol & Intens Care Med CCM CVK, Berlin, Germany.;Tech Univ Munich, Sch Med, Klinikum Rechts Isar, Dept Anesthesiol & Intens Care Med, Munich, Bavaria, Germany.
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Charite Univ Med Berlin, Berlin, Germany;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Dept Anesthesiol & Intens Care Med CCM CVK, Berlin, Germany. Univ Basel, Dept Biomed, Res Platform Mol & Cognit Neurosci MCN, Basel, Switzerland. (creator_code:org_t)
- Springer, 2023
- 2023
- Engelska.
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Ingår i: Annals of Intensive Care. - : Springer. - 2110-5820. ; 13:1
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background Early mobilisation (EM) is an intervention that may improve the outcome of critically ill patients. There is limited data on EM in COVID-19 patients and its use during the first pandemic wave. Methods This is a pre-planned subanalysis of the ESICM UNITE-COVID, an international multicenter observational study involving critically ill COVID-19 patients in the ICU between February 15th and May 15th, 2020. We analysed variables associated with the initiation of EM (within 72 h of ICU admission) and explored the impact of EM on mortality, ICU and hospital length of stay, as well as discharge location. Statistical analyses were done using (generalised) linear mixed-effect models and ANOVAs. Results Mobilisation data from 4190 patients from 280 ICUs in 45 countries were analysed. 1114 (26.6%) of these patients received mobilisation within 72 h after ICU admission; 3076 (73.4%) did not. In our analysis of factors associated with EM, mechanical ventilation at admission (OR 0.29; 95% CI 0.25, 0.35; p = 0.001), higher age (OR 0.99; 95% CI 0.98, 1.00; p <= 0.001), pre-existing asthma (OR 0.84; 95% CI 0.73, 0.98; p = 0.028), and pre-existing kidney disease (OR 0.84; 95% CI 0.71, 0.99; p = 0.036) were negatively associated with the initiation of EM. EM was associated with a higher chance of being discharged home (OR 1.31; 95% CI 1.08, 1.58; p = 0.007) but was not associated with length of stay in ICU (adj. difference 0.91 days; 95% CI - 0.47, 1.37, p = 0.34) and hospital (adj. difference 1.4 days; 95% CI - 0.62, 2.35, p = 0.24) or mortality (OR 0.88; 95% CI 0.7, 1.09, p = 0.24) when adjusted for covariates. Conclusions Our findings demonstrate that a quarter of COVID-19 patients received EM. There was no association found between EM in COVID-19 patients' ICU and hospital length of stay or mortality. However, EM in COVID-19 patients was associated with increased odds of being discharged home rather than to a care facility.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
Nyckelord
- COVID-19
- SARS-CoV-2
- Early ambulation
- Critical care
- Intensive care units
- Physical therapy specialty
- Bed rest
- Mobilisation
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Kloss, Philipp
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Lindholz, Maximi ...
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Milnik, Annette
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Azoulay, Elie
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Cecconi, Maurizi ...
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Citerio, Giusepp ...
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visa fler...
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De Corte, Thomas
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Duska, Frantisek
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Galarza, Laura
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Greco, Massimili ...
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Girbes, Armand R ...
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Kesecioglu, Joze ...
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Mellinghoff, Joh ...
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Ostermann, Marli ...
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Pellegrini, Mari ...
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Teboul, Jean-Lou ...
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De Waele, Jan
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Wong, Adrian
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Schaller, Stefan ...
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MEDICIN OCH HÄLS ...
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