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Scenarios for 3D pr...
Scenarios for 3D printing of personalized medicines : A case study
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- Beer, Netta (författare)
- Univ Copenhagen, Dept Pharm, Copenhagen, Denmark.
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- Hegger, Ingrid (författare)
- Natl Inst Publ Hlth & Environm RIVM, Ctr Hlth Protect, Bilthoven, Netherlands.
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- Kaae, Susanne (författare)
- Univ Copenhagen, Dept Pharm, Copenhagen, Denmark.
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- De Bruin, Marie Louise (författare)
- Natl Inst Publ Hlth & Environm RIVM, Ctr Hlth Protect, Bilthoven, Netherlands.;Univ Copenhagen, Copenhagen Ctr Regulatory Sci, Dept Pharm, Copenhagen, Denmark. Univ Utrecht, Utrecht Inst Pharmaceut Sci, Div Pharmacoepidemiol & Clin Pharmacol, Utrecht, Netherlands.
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- Genina, Natalja (författare)
- Univ Copenhagen, Dept Pharm, Copenhagen, Denmark.
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- Leonardo Alves, Teresa (författare)
- Natl Inst Publ Hlth & Environm RIVM, Ctr Hlth Protect, Bilthoven, Netherlands.
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- Hoebert, Joelle (författare)
- Natl Inst Publ Hlth & Environm RIVM, Ctr Hlth Protect, Bilthoven, Netherlands.
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- Kälvemark Sporrong, Sofia (författare)
- Uppsala universitet,Institutionen för farmaci,Univ Copenhagen, Dept Pharm, Copenhagen, Denmark
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Univ Copenhagen, Dept Pharm, Copenhagen, Denmark Natl Inst Publ Hlth & Environm RIVM, Ctr Hlth Protect, Bilthoven, Netherlands. (creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
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Ingår i: Exploratory Research in Clinical and Social Pharmacy. - : Elsevier. - 2667-2766. ; 4
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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Abstract
Ämnesord
Stäng
- Background3D printing is a promising new technology for medicines' production. It employs additive manufacturing techniques, and is ideal for producing personalized medicines (e.g., patient-tailored dose, dosage form, drug release kinetics).ObjectiveTo investigate how 3D printing technologies can be implemented in a European pharmaceutical system, by suggesting different scenarios and assessing aspects that could affect its implementation.MethodQualitative, semi-structured interviews were conducted with key stakeholders (e.g., from ministry, authorities, research organizations, pharmacies) in the Netherlands to elicit perspectives on 3D printing of personalized medicines. The Netherlands were chosen since it has a strong tradition in compounding. Five general scenarios were investigated: placing the 3D printers in industry, community pharmacies, hospital pharmacies, compounding facilities, and in patients' homes. Content analysis was used, building on verbatim transcripts.ResultsFifteen stakeholders were interviewed. Regulatory, economic, ethical and organizational challenges were identified to varying degrees in the different scenarios. The industry and home scenarios were associated with the most challenges, hospital pharmacies and compounding facilities with the least. Other important aspects identified were the role of community pharmacies, and who should design the tablets to be printed.ConclusionAll potential scenarios for 3D printing of personalized medicines include challenges. These should be taken into account when pursuing the use of 3D printing of medicine.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmaceutiska vetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmaceutical Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
Nyckelord
- Personalized medicine
- Compounding
- Magistral medicines
- 3D printing
- Societal impact
- Qualitative interviews
- Extemporaneous preparation
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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