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Modification of Food Allergy on the Associations between Early Life Exposure to Size-Specific Particulate Matter and Childhood Allergic Rhinitis

Wu, Chuansha (författare)
Wuhan Univ Sci & Technol, Sch Publ Hlth, Dept Environm Hyg & Occupat Med, Wuhan 430065, Peoples R China.;Wuhan Univ Sci & Technol, Hubei Key Lab Occupat Hazard Identificat & Control, Wuhan 430065, Hubei, Peoples R China.
Tang, Haoran (författare)
Wuhan Univ Sci & Technol, Sch Publ Hlth, Dept Environm Hyg & Occupat Med, Wuhan 430065, Peoples R China.;Wuhan Univ Sci & Technol, Hubei Key Lab Occupat Hazard Identificat & Control, Wuhan 430065, Hubei, Peoples R China.
Wei, Jing (författare)
Univ Maryland, Earth Syst Sci Interdisciplinary Ctr, Dept Atmospher & Ocean Sci, College Pk, MD 20740 USA.
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Chen, Hao (författare)
Wuhan Univ Sci & Technol, Sch Publ Hlth, Dept Environm Hyg & Occupat Med, Wuhan 430065, Peoples R China.;Wuhan Univ Sci & Technol, Hubei Key Lab Occupat Hazard Identificat & Control, Wuhan 430065, Hubei, Peoples R China.
Zhao, Zhuohui (författare)
Fudan Univ, Sch Publ Hlth, Dept Environm Hlth, Shanghai 200030, Peoples R China.
Norbäck, Dan (författare)
Uppsala universitet,Arbets- och miljömedicin
Zhang, Xin (författare)
Shanxi Univ, Res Ctr Environm Sci & Engn, Taiyuan 030006, Peoples R China.
Lu, Chan (författare)
Cent South Univ, Xiangya Med Coll, Sch Publ Hlth, Dept Occupat & Environm Hlth, Changsha 410078, Peoples R China.
Yu, Wei (författare)
Chongqing Univ, Joint Int Res Lab Green Bldg & Built Environm, Minist Educ, Chongqing 400045, Peoples R China.
Wang, Tingting (författare)
Shanghai Univ Med & Hlth Sci, Sch Nursing & Hlth Management, Shanghai 201318, Peoples R China.
Zheng, Xiaohong (författare)
Southeast Univ, Sch Energy & Environm, Nanjing 210096, Peoples R China.
Li, Rui (författare)
Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
Zhang, Yunquan (författare)
Wuhan Univ Sci & Technol, Hubei Key Lab Occupat Hazard Identificat & Control, Wuhan 430065, Hubei, Peoples R China.;Wuhan Univ Sci & Technol, Sch Publ Hlth, Dept Epidemiol & Biostat, Wuhan 430065, Peoples R China.
Zhang, Ling (författare)
Wuhan Univ Sci & Technol, Sch Publ Hlth, Dept Environm Hyg & Occupat Med, Wuhan 430065, Peoples R China.;Wuhan Univ Sci & Technol, Hubei Key Lab Occupat Hazard Identificat & Control, Wuhan 430065, Hubei, Peoples R China.
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Wuhan Univ Sci & Technol, Sch Publ Hlth, Dept Environm Hyg & Occupat Med, Wuhan 430065, Peoples R China;Wuhan Univ Sci & Technol, Hubei Key Lab Occupat Hazard Identificat & Control, Wuhan 430065, Hubei, Peoples R China. Univ Maryland, Earth Syst Sci Interdisciplinary Ctr, Dept Atmospher & Ocean Sci, College Pk, MD 20740 USA. (creator_code:org_t)
American Chemical Society (ACS), 2024
2024
Engelska.
Ingår i: Environmental Science and Technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 58:4, s. 1813-1822
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Previous studies have reported the association between particulate matter (PM) and childhood allergic rhinitis (AR). However, it is unclear whether food allergy (FA) modifies the PM-AR association. We aimed at evaluating the effect of the modification of FA on PM-AR association in preschool children. We adopted a cross-sectional study and conducted a questionnaire survey among preschool children aged 3-6 years in 7 cities in China from June 2019 to June 2020 to collect information on AR and FA. We used a combination of multilevel logistic regression and restricted cubic spline functions to quantitatively assess whether FA modifies the associations between size-specific PM exposure (1 x 1 km) and the risk of AR. The adjusted odds ratios (ORs) for AR among the children with FA as per a 10 mu g/m(3) increase in early life PM1, PM2.5, and PM10 were significantly higher than the corresponding ORs among the children without FA [e.g., OR: 1.58, 95% CI: (1.32, 1.90) vs 1.29, 95% CI: (1.18, 1.41), per 10 mu g/m(3) increase in PM1]. The interactions between FA and size-specific PM exposure and their effects on AR were statistically significant (all p-int < 0.001). FA, as an important part of the allergic disease progression, may modify the PM-AR association in preschool children.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

PM1
PM2.5
modification
food allergy
allergic rhinitis

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