Polycystic ovary syndrome and risk of pre‐eclampsia: A national register‐based cohort study

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:DiVA.org:uu-524742" > Polycystic ovary sy...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Valdimarsdottir, RagnheidurUppsala universitet,Reproduktiv hälsa (author)

Polycystic ovary syndrome and risk of pre‐eclampsia : A national register‐based cohort study

Article/chapterEnglish2023

Publisher, publication year, extent ...

John Wiley & Sons,2023
electronicrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:uu-524742
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-524742URI
https://doi.org/10.1111/1471-0528.17734DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Objective: To explore whether the association between polycystic ovary syndrome (PCOS) and pre-eclampsia depends on treated clinical hyperandrogenism and whether PCOS is associated with different subtypes of pre-eclampsia.Design: Nationwide register-based cohort study.Setting: Sweden.Population: Nulliparous women with PCOS (n = 22 947) and non-PCOS controls (n = 115 272) giving singleton birth at ≥22 gestational weeks during 1997-2015. Treated clinical hyperandrogenism was defined as filled prescriptions of anti-androgenic drugs during 2005-2017 (n = 2301 among PCOS women).Methods: The risk of pre-eclampsia was estimated with conditional logistic regression, expressed as adjusted odds ratio (OR) with 95% confidence interval (CI). Adjustments were performed individually for confounders and predictors.Main outcome measures: Overall pre-eclampsia. Early/late (delivery <34/≥34 weeks) pre-eclampsia. Pre-eclampsia with or without a small-for-gestational-age (SGA) infant.Results: Compared with controls, women with PCOS had a 29% increased risk of pre-eclampsia (predictor adjusted OR 1.29, 95% CI 1.20-1.39), with similar risk estimates for PCOS women with and without treated clinical hyperandrogenism. The association between PCOS and early pre-eclampsia seemed stronger than its association with late pre-eclampsia (predictor adjusted OR 1.64 (95% CI 1.33-2.02) and 1.26 (95% CI 1.17-1.37). Additionally, the association seemed slightly stronger between PCOS and pre-eclampsia in women with an SGA infant than without.Conclusions: Women with PCOS face an increased risk for pre-eclampsia, especially early pre-eclampsia and pre-eclampsia with an SGA infant. We were unable to determine on the basis of available data, whether hyperandrogenism is associated with pre-eclampsia.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reproduktionsmedicin och gynekologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Obstetrics, Gynaecology and Reproductive Medicine hsv//eng
hyperandrogenism
polycystic ovary syndrome
pre-eclampsia
pregnancy complications
preterm birth
small for gestational age.
Obstetrik och gynekologi
Obstetrics and Gynaecology

Added entries (persons, corporate bodies, meetings, titles ...)

Vanky, EszterDepartment of Clinical and Molecular Medicine Norwegian University of Science and Technology Trondheim Norway;Department of Obstetrics and Gynaecology St. Olavs Hospital, Trondheim University Hospital Trondheim Norway (author)
Elenis, Evangelia,1983-Uppsala universitet,Reproduktiv hälsa(Swepub:uu)evael941 (author)
Lindström, Linda,1978-Uppsala universitet,Klinisk obstetrik(Swepub:uu)linli329 (author)
Junus, Katja,1982-Uppsala universitet,Klinisk obstetrik(Swepub:uu)katju360 (author)
Jonsson, Maria,1966-Uppsala universitet,Klinisk obstetrik(Swepub:uu)marjo155 (author)
Sundström Poromaa, Inger,1964-Uppsala universitet,Reproduktiv hälsa(Swepub:uu)inspo702 (author)
Wikström, Anna-Karin,1965-Uppsala universitet,Klinisk obstetrik(Swepub:uu)annwi179 (author)
Uppsala universitetReproduktiv hälsa (creator_code:org_t)

Related titles

In:British Journal of Obstetrics and Gynecology: John Wiley & Sons1470-03281471-0528

Internet link

Find in a library

British Journal of Obstetrics and Gynecology (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Valdimarsdottir, ...; Vanky, Eszter; Elenis, Evangeli ...; Lindström, Linda ...; Junus, Katja, 19 ...; Jonsson, Maria, ...; show more...; Sundström Poroma ...; Wikström, Anna-K ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Obstetrics Gynae ...

Articles in the publication: British Journal ...

By the university: Uppsala University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se