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Global mortality an...
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Waeijen-Smit, KikiCiro, Dept Res & Dev, Horn, Netherlands.;Maastricht Univ Med Ctr MUMC, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Fac Hlth Med & Life Sci, Maastricht, Netherlands.
(författare)
Global mortality and readmission rates following COPD exacerbation-related hospitalisation : a meta-analysis of 65 945 individual patients
- Artikel/kapitelEngelska2024
Förlag, utgivningsår, omfång ...
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European Respiratory Society,2024
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-525934
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-525934URI
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https://doi.org/10.1183/23120541.00838-2023DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Background Exacerbations of COPD (ECOPD) have a major impact on patients and healthcare systems across the world. Precise estimates of the global burden of ECOPD on mortality and hospital readmission are needed to inform policy makers and aid preventive strategies to mitigate this burden. The aims of the present study were to explore global in-hospital mortality, post-discharge mortality and hospital readmission rates after ECOPD-related hospitalisation using an individual patient data meta-analysis (IPDMA) design. Methods A systematic review was performed identifying studies that reported in-hospital mortality, postdischarge mortality and hospital readmission rates following ECOPD-related hospitalisation. Data analyses were conducted using a one-stage random-effects meta-analysis model. This study was conducted and reported in accordance with the PRISMA-IPD statement. Results Data of 65 945 individual patients with COPD were analysed. The pooled in-hospital mortality rate was 6.2%, pooled 30-, 90- and 365-day post-discharge mortality rates were 1.8%, 5.5% and 10.9%, respectively, and pooled 30-, 90- and 365-day hospital readmission rates were 7.1%, 12.6% and 32.1%, respectively, with noticeable variability between studies and countries. Strongest predictors of mortality and hospital readmission included noninvasive mechanical ventilation and a history of two or more ECOPD-related hospitalisations < 12 months prior to the index event. Conclusions This IPDMA stresses the poor outcomes and high heterogeneity of ECOPD-related hospitalisation across the world. Whilst global standardisation of the management and follow-up of ECOPD-related hospitalisation should be at the heart of future implementation research, policy makers should focus on reimbursing evidence-based therapies that decrease (recurrent) ECOPD.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Crutsen, MiekeMUMC, Pulm Funct & Exercise Testing Lab, Maastricht, Netherlands.
(författare)
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Keene, SpencerCiro, Dept Res & Dev, Horn, Netherlands.;Univ Birmingham, Inst Appl Hlth Res, Coll Med & Dent Sci, Birmingham, England.;MUMC, Dept Clin Pharm & Toxicol, Maastricht, Netherlands.
(författare)
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Miravitlles, MarcHosp Univ Vall dHebron, Vall dHebron Inst Recerca, Pneumol Dept, Ciber Enfermedades Resp CIBERES, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain.
(författare)
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Crisafulli, ErnestoUniv Verona, Dept Med, Resp Med Unit, Verona, Italy.
(författare)
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Torres, AntoniHosp Clin Barcelona, Dept Pulmonol, Barcelona, Spain.;Univ Barcelona, Barcelona, Spain.;CIBERES, Inst Invest Biomed August Pi & Sunyer, Inst Catalana Invest & Estudios Avanzados, Barcelona, Spain.
(författare)
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Mueller, ChristianUniv Basel, Univ Hosp Basel, Cardiovasc Res Inst Base, Dept Cardiol, Basel, Switzerland.
(författare)
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Schuetz, PhilippKantonsspital Aarau, Med Univ Dept, Aarau, Switzerland. Univ Basel, Fac Med, Basel, Switzerland.
(författare)
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Ringbaek, Thomas J.Copenhagen Univ Hosp Hvidovre, Dept Resp Med, Hvidovre, Denmark.
(författare)
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Fabbian, FabioUniv Ferrara, Univ Hosp Ferrara, Dept Med Sci Pharm & Prevent, Fac Med, Ferrara, Italy.
(författare)
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Mekov, EvgeniMed Univ Sofia, Dept Occupat Dis, Sofia, Bulgaria.
(författare)
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Harries, Timothy H.Kings Coll London, Sch Life Course & Populat Sci, Dept Populat Hlth Sci, London, England.
(författare)
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Lun, Chung-TatAlice Ho Miu Ling Nethersole Hosp, Dept Med & ICU, Hong Kong, Peoples R China.
(författare)
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Ergan, BegumDokuz Eylul Univ, Div Crit Care, Dept Pulm & Crit Care, Fac Med, Izmir, Turkiye.
(författare)
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Esteban, CristobalHosp Galdakao, Resp Dept, Galdakao, Spain.;Inst BioCruces Bizkaia, Baracaldo, Spain.;Red Invest Cronicidad Atenc Primaria & Promoc Sal, Red Invest Serv Sanitarios & Enfermedade Cron, Bizkaia, Spain.
(författare)
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Quintana Lopez, Jose M.Red Invest Cronicidad Atenc Primaria & Promoc Sal, Red Invest Serv Sanitarios & Enfermedade Cron, Bizkaia, Spain.;Hosp Galdakao Usansolo, Unidad Invest, Galdakao, Spain.
(författare)
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Lopez-Campos, Jose LuisUniv Seville, Hosp Univ Virgen Rocio, Unidad Med Quirurg Enfermedades Resp, Inst Biomed Sevilla, Seville, Spain.;Inst Salud Carlos III, CIBERES, Madrid, Spain.
(författare)
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Chang, Catherina L.Waikato Hosp, Dept Resp Med, Hamilton, New Zealand.
(författare)
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Hancox, Robert J.Waikato Hosp, Dept Resp Med, Hamilton, New Zealand.;Univ Otago, Dept Prevent & Social Med, Dunedin, New Zealand.
(författare)
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Shafuddin, EskandarainWaikato Hosp, Dept Resp Med, Hamilton, New Zealand.
(författare)
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Ellis, HollieWaikato Hosp, Dept Resp Med, Hamilton, New Zealand.
(författare)
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Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning(Swepub:uu)chrisjn
(författare)
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Ulrik, Charlotte SuppliCopenhagen Univ Hosp Hvidovre, Dept Resp Med, Hvidovre, Denmark.
(författare)
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Gudmundsson, GunnarLandspitali Natl Univ Hosp Iceland, Reykjavik, Iceland.;Univ Iceland, Fac Med, Sch Hlth Sci, Reykjavik, Iceland.
(författare)
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Epstein, DannyRambam Hlth Care Campus, Crit Care Div, Haifa, Israel.
(författare)
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Dominguez, JoseHosp Galdakao Usansolo, Unidad Invest, Galdakao, Spain.
(författare)
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Lacoma, AliciaUniv Autonoma Barcelona, Inst Invest Germans Trias & Pujol, Hosp Univ Germans Trias & Pujol, Serv Microbiol,CIBERES, Barcelona, Spain.
(författare)
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Osadnik, ChristianMonash Univ, Dept Physiotherapy, Clayton, Vic, Australia.
(författare)
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Alia, InmaculadaHosp Univ Getafe, Intens Care Units, CIBERES, Getafe, Spain.
(författare)
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Spannella, FrancescoIRCCS INRCA, Internal Med & Geriatr Hypertens Excellence Ctr, European Soc Hypertens, Ancona, Italy.;Univ Politecn Marche, Dept Clin & Mol Sci, Ancona, Italy.
(författare)
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Karakurt, ZuhalUniv Hlth Sci Istanbul, Resp Crit Care Unit, Sureyyapasa Chest Dis & Thorac Surg Training & Re, Istanbul, Turkiye.
(författare)
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Mehravaran, HosseinMazandaran Univ Med Sci, Pulm & Crit Care Div, Dept Internal Med, Sari, Iran.
(författare)
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Utens, CecileLibra, Rehabil & Audiol, Eindhoven, Netherlands.
(författare)
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de Kruif, Martijn D.Zuyderland Med Ctr, Dept Pulm Med, Heerlen, Netherlands.
(författare)
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Ko, Fanny Wai SanChinese Univ Hong Kong, Dept Med & Therapeut, Prince Wales Hosp, Fac Med, Hong Kong, Peoples R China.
(författare)
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Trethewey, Samuel P.Gloucestershire Hosp NHS Fdn Trust, Cheltenham, England.;Univ Exeter, Exeter, England.
(författare)
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Turner, Alice M.Univ Birmingham, Inst Appl Hlth Res, Birmingham, England.;Univ Hosp Birmingham NHS Fdn Trust, Birmingham, England.
(författare)
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Bumbacea, DragosCarol Davila Univ Med & Pharm, Elias Emergency Univ Hosp, Dept Pneumol & Acute Resp Care, Bucharest, Romania.
(författare)
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Murphy, Patrick B.Guys & St Thomas NHS Fdn Trust, Lane Fox Unit, London, England.;Kings Coll London, Ctr Human & Appl Physiol Sci, London, England.
(författare)
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Vermeersch, KristinaKatholieke Univ Leuven, Dept Chron Dis Metab & Ageing, Res Grp BREATHE, Leuven, Belgium.
(författare)
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Zilberman-Itskovich, ShaniAssaf Harofeh Shamir Med Ctr, Nephrol Div, Beer Yaagov, Israel.;Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel.
(författare)
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Steer, JohnNewcastle Univ, Translat & Clin Res Inst, Newcastle Upon Tyne, England.;North Tyneside Gen Hosp, Resp Dept, North Shields, England.
(författare)
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Echevarria, CarlosNewcastle Univ, Translat & Clin Res Inst, Newcastle Upon Tyne, England.;Royal Victoria Infirm, Resp Dept, Newcastle Upon Tyne, England.
(författare)
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Bourke, Stephen C.Newcastle Univ, Translat & Clin Res Inst, Newcastle Upon Tyne, England.;North Tyneside Gen Hosp, Resp Dept, North Shields, England.
(författare)
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Lane, NicholasNewcastle Univ, Translat & Clin Res Inst, Newcastle Upon Tyne, England.;Royal Victoria Infirm, Resp Dept, Newcastle Upon Tyne, England.
(författare)
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de Batlle, JordiInst Recerca Biomed Lleida Fundacio Dr Pifarre, Grp Translat Res Resp Med, Lleida, Spain.;CIBERES, Madrid, Spain.
(författare)
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Sprooten, Roy T. M.MUMC, Dept Resp Med, Maastricht, Netherlands.
(författare)
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Russell, RichardKings Coll London, Sch Immunol & Microbial Sci, Guys Campus, London, England.
(författare)
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Faverio, PaolaUniv Milano Bicocca, ASST Monza, San Gerardo Hosp, Resp Unit, Monza, Italy.
(författare)
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Cross, Jane L.Univ East Anglia, Fac Med & Hlth, Norwich, England.
(författare)
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Prins, Hendrik J.Libra, Dept PMR Rehabil & Audiol, Eindhoven, Netherlands.;Anna Hosp, Dept PMR, Geldrop, Netherlands.;Catharina Hosp, Dept PMR, Eindhoven, Netherlands.
(författare)
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Spruit, Martijn A.Ciro, Dept Res & Dev, Horn, Netherlands.;Maastricht Univ Med Ctr MUMC, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Fac Hlth Med & Life Sci, Maastricht, Netherlands.
(författare)
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Simons, Sami O.Maastricht Univ Med Ctr MUMC, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Fac Hlth Med & Life Sci, Maastricht, Netherlands.
(författare)
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Houben-Wilke, SarahCiro, Dept Res & Dev, Horn, Netherlands.
(författare)
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Franssen, Frits M. E.Ciro, Dept Res & Dev, Horn, Netherlands.;Maastricht Univ Med Ctr MUMC, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Fac Hlth Med & Life Sci, Maastricht, Netherlands.
(författare)
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Ciro, Dept Res & Dev, Horn, Netherlands.;Maastricht Univ Med Ctr MUMC, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Fac Hlth Med & Life Sci, Maastricht, Netherlands.MUMC, Pulm Funct & Exercise Testing Lab, Maastricht, Netherlands.
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:ERJ Open Research: European Respiratory Society10:12312-0541
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Till lärosätets databas
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Waeijen-Smit, Ki ...
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Crutsen, Mieke
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Keene, Spencer
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Miravitlles, Mar ...
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Crisafulli, Erne ...
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Torres, Antoni
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visa fler...
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Mueller, Christi ...
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Schuetz, Philipp
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Ringbaek, Thomas ...
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Fabbian, Fabio
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Mekov, Evgeni
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Harries, Timothy ...
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Lun, Chung-Tat
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Ergan, Begum
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Esteban, Cristob ...
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Quintana Lopez, ...
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Lopez-Campos, Jo ...
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Chang, Catherina ...
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Hancox, Robert J ...
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Shafuddin, Eskan ...
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Ellis, Hollie
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Janson, Christer
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Ulrik, Charlotte ...
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Gudmundsson, Gun ...
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Epstein, Danny
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Dominguez, Jose
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Lacoma, Alicia
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Osadnik, Christi ...
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Alia, Inmaculada
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Spannella, Franc ...
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Karakurt, Zuhal
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Mehravaran, Hoss ...
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Utens, Cecile
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de Kruif, Martij ...
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Ko, Fanny Wai Sa ...
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Trethewey, Samue ...
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Turner, Alice M.
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Bumbacea, Dragos
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Murphy, Patrick ...
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Vermeersch, Kris ...
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Zilberman-Itskov ...
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Steer, John
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Echevarria, Carl ...
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Bourke, Stephen ...
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Lane, Nicholas
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de Batlle, Jordi
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Sprooten, Roy T. ...
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Russell, Richard
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Faverio, Paola
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Cross, Jane L.
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Prins, Hendrik J ...
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Spruit, Martijn ...
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Simons, Sami O.
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Houben-Wilke, Sa ...
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Franssen, Frits ...
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visa färre...
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