onr:"swepub:oai:DiVA.org:uu-526966"
Search: onr:"swepub:oai:DiVA.org:uu-526966" > Genetic Polymorphis...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Siljestam, Mattias,1989-Uppsala universitet,Zooekologi,Rueffler group (author)
Genetic Polymorphism – A Result of LocalAdaptation or Heterozygote Advantage?
- BookEnglish
Publisher, publication year, extent ...
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-526966
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-526966URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Stable coexistence of different self-reproducing entities requires negative frequency dependence, such that each type has an advantage when rare. In community ecology, the entities of interest are species or morphs, and negative frequency dependence arises from competition for limiting factors. In this scenario, coexistence is generally interpreted as a result of local adaptation or niche differentiation. In diploid organisms, different alleles in a specific locus can coexist if heterozygote individuals have an advantage over homozygotes. Here, at the allelic level, negative frequency dependence arises because rare alleles tend to occur in a coalition with alleles different from themselves. A classical example are MHC genes where a heterozygote advantage arises if different alleles offer protection against different sets of pathogens. Coexistence of this type can be interpreted as facilitation or division of labour. Here, we study evolution of MHC alleles in a species occurring in two habitats with different pathogen communities. Our aim is to illustrate that both types of frequency-dependent selection can drive the evolution and maintenance of allelic polymorphism, with local adaptation dominating when migration between habitats is rare and MHC alleles have close to additive effects on survival, and facilitation dominating when migration occurs frequently and alleles that offer better protection against a given pathogen community have a more than additive effect on survival.
Subject headings and genre
- NATURVETENSKAP Biologi Evolutionsbiologi hsv//swe
- NATURAL SCIENCES Biological Sciences Evolutionary Biology hsv//eng
- balancing selection
- heterozygote advantage
- migration
- patch model
- MHC
- Biologi med inriktning mot zooekologi
- Biology with specialization in Animal Ecology
- Biologi med inriktning mot zooekologi
- Biology with specialization in Animal Ecology
Added entries (persons, corporate bodies, meetings, titles ...)
- Rüffler, ClausUppsala universitet,Zooekologi,Rueffler group(Swepub:uu)claru454 (author)
- Uppsala universitetZooekologi (creator_code:org_t)
Internet link
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Siljestam, Matti ...
- Rüffler, Claus
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
- and Evolutionary Bio ...
- By the university
- Uppsala University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
