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  • Di Martino, ElenaLinköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Karolinska Inst, Sweden (author)

Inflammatory, metabolic, and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia

  • Article/chapterEnglish2024

Publisher, publication year, extent ...

  • CELL PRESS,2024
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-206759
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-206759URI
  • https://doi.org/10.1016/j.isci.2024.109346DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:238500830URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:158712470URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies|Jane and Dan Olsson Foundation; Lars Hierta Memorial Foundation [FO2015-0469, FO2016-0326]; Tore Nilsons Stiftelse for Medicinsk Forskning [2015-00263, 2016-00403]; Foundation Tornspiran; Ake Wiberg Foundation [M19-0593, M20-0193]; O.E. och Edla Johanssons Vetenskapliga Stiftelse; Samariten Foundation; Gamla Tjanarinnor [2019-00924, 2020-01090, 2021-01240]; Olle Engkvist Foundation [198_0418]; Swedish Research Council [2018-06156, 2021-00993, 2021-01756]
  • Neonatal hypoxia-ischemia (HI) is a major cause of perinatal death and long-term disabilities worldwide. in the hippocampi of mice subjected to HI at postnatal day 9. Using inflammatory pathway and transcripcells isolated from hippocampi showed a partial convergence. Interestingly, microglia-specific genes in but not in females during the experimental time frame. These results highlight the importance of further investigations on metabolic rewiring to pave the way for future interventions in asphyxiated neonates.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Ambikan, AnoopKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Ramskold, DanielKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Umekawa, TakashiKarolinska Inst, Sweden (author)
  • Giatrellis, SarantisKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Vacondio, DavideKarolinska Inst, Sweden; Vrije Univ Amsterdam, Netherlands (author)
  • Romero, Alejandro LastraKarolinska Inst, Sweden (author)
  • Galan, Marta GomezKarolinska Inst, Sweden (author)
  • Sandberg, RickardKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Ådén, UlrikaKarolinska Institutet,Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden(Swepub:liu)ulrad42 (author)
  • Lauschke, Volker M.Karolinska Institutet,Karolinska Inst, Sweden; Dr Margarete Fischer Bosch Inst Clin Pharmacol, Germany; Univ Tubingen, Germany (author)
  • Neogi, UjjwalKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Blomgren, KlasKarolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden (author)
  • Kele, JuliannaKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Linköpings universitetAvdelningen för barns och kvinnors hälsa (creator_code:org_t)

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  • In:iScience: CELL PRESS27:42589-0042

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