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Prenatal and postna...
Prenatal and postnatal early life exposure to greenness and particulate matter of different size fractions in relation to childhood rhinitis : A multi-center study in China
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- Yang, Liu (författare)
- Shanxi Univ, Inst Environm Sci, Taiyuan 030006, Peoples R China.
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- Chen, Han (författare)
- Fudan Univ, Sch Publ Hlth, Dept Environm Hlth, NHC Key Lab Hlth Technol Assessment, Shanghai 200032, Peoples R China.
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- Gao, Huiyu (författare)
- Shanxi Univ, Inst Environm Sci, Taiyuan 030006, Peoples R China.
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- Wang, Ying (författare)
- Shanxi Univ, Inst Environm Sci, Taiyuan 030006, Peoples R China.
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- Chen, Tianyi (författare)
- Fudan Univ, Sch Publ Hlth, Dept Environm Hlth, NHC Key Lab Hlth Technol Assessment, Shanghai 200032, Peoples R China.
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- Svartengren, Magnus (författare)
- Uppsala Univ Hosp, Dept Occupat & Environm Med, Uppsala, Sweden
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- Norbäck, Dan (författare)
- Uppsala Univ Hosp, Dept Occupat & Environm Med, Uppsala, Sweden
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- Wei, Jing (författare)
- Univ Maryland, Earth Syst Sci Interdisciplinary Ctr, Dept Atmospher & Ocean Sci, College Pk, MD 20740 USA.
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- Zheng, Xiaohong (författare)
- Southeast Univ, Sch Energy & Environm, Nanjing 210096, Peoples R China.
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- Zhang, Ling (författare)
- Wuhan Univ Sci & Technol, Med Coll, Sch Publ Hlth, Dept Environm Hyg & Occupat Med, Wuhan 430065, Peoples R China.
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- Lu, Chan (författare)
- Cent South Univ, Xiangya Sch Publ Hlth, Dept Occupat & Environm Hlth, Changsha 410078, Peoples R China.
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- Yu, Wei (författare)
- Chongqing Univ, Key Lab Three Gorges Reservoir Reg Ecoenvironm, Chongqing 400030, Peoples R China.
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- Wang, Tingting (författare)
- Shanghai Univ Med & Hlth Sci, Sch Nursing & Hlth Management, Shanghai 201318, Peoples R China.
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- Ji, John S. (författare)
- Tsinghua Univ, Vanke Sch Publ Hlth, Beijing 100084, Peoples R China.
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- Meng, Xia (författare)
- Fudan Univ, Sch Publ Hlth, Dept Environm Hlth, NHC Key Lab Hlth Technol Assessment, Shanghai 200032, Peoples R China.;Shanghai Typhoon Inst, Key Lab Publ Hlth Safety Minist Educ, Shanghai Key Lab Meteorol & Hlth, Shanghai 200030, Peoples R China.;Fudan Univ, IRDR Int Ctr Excellence Risk Interconnect & Govern, Shanghai 200438, Peoples R China.
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- Zhao, Zhuohui (författare)
- Fudan Univ, Sch Publ Hlth, Dept Environm Hlth, NHC Key Lab Hlth Technol Assessment, Shanghai 200032, Peoples R China.;Shanghai Typhoon Inst, Key Lab Publ Hlth Safety Minist Educ, Shanghai Key Lab Meteorol & Hlth, Shanghai 200030, Peoples R China.;Fudan Univ, IRDR Int Ctr Excellence Risk Interconnect & Govern, Shanghai 200438, Peoples R China.
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- Zhang, Xin (författare)
- Shanxi Univ, Inst Environm Sci, Taiyuan 030006, Peoples R China.
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Shanxi Univ, Inst Environm Sci, Taiyuan 030006, Peoples R China Fudan Univ, Sch Publ Hlth, Dept Environm Hlth, NHC Key Lab Hlth Technol Assessment, Shanghai 200032, Peoples R China. (creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: Science of the Total Environment. - : Elsevier. - 0048-9697 .- 1879-1026. ; 938
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The impact of early life exposure to residential greenness on childhood rhinitis and its interaction with particulate matter (PM) of different size fractions remain inconsistent. Herein, we recruited 40,486 preschool children from randomly selected daycare centers in 7 cities in China from 2019 to 2020, and estimated exposure to residential greenness by the normalized difference vegetation index (NDVI) with a 500 m buffer. Exposure to ambient PM (PM1, PM2.5, and PM10) was evaluated using a satellite-based prediction model (daily, at a resolution of 1 km × 1 km). By mixed-effect logistic regression, NDVI values during pregnancy, in the first (0–1 year old) and the second (1–2 years old) year of life were negatively associated with lifetime rhinitis (LR) and current rhinitis (CR) (P < 0.001). PM in the same time windows was associated with increased risks of LR and CR in children, with smaller size fraction of PM showing greater associations. The negative associations between prenatal and postnatal NDVI and LR and CR in preschool children remained robust after adjusting for concomitant exposure to PM, whereas the associations of postnatal NDVI and rhinitis showed significant interactions with PM. At lower levels of PM, postnatal NDVI remained negatively associated with rhinitis and was partly mediated by PM (10.0–40.9 %), while at higher levels of PM, the negative associations disappeared or even turned positive. The cut-off levels of PM were identified for each size fraction of PM. In conclusion, prenatal exposure to greenness had robust impacts in lowering the risk of childhood rhinitis, while postnatal exposure to greenness depended on the co-exposure levels to PM. This study revealed the complex interplay of greenness and PM on rhinitis in children. The exposure time window in prenatal or postnatal period and postnatal concomitant PM levels played important roles in influencing the associations between greenness, PM and rhinitis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- Allergy
- Air pollution
- Children
- Greenness
- Interaction
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- art (ämneskategori)
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Yang, Liu
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Chen, Han
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Gao, Huiyu
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Wang, Ying
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Chen, Tianyi
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Svartengren, Mag ...
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visa fler...
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Norbäck, Dan
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Wei, Jing
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Zheng, Xiaohong
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Zhang, Ling
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Lu, Chan
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Yu, Wei
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Wang, Tingting
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Ji, John S.
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Meng, Xia
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Zhao, Zhuohui
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Zhang, Xin
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