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Kaempferol and athe...
Kaempferol and atherosclerosis : From mechanism to medicine
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- Chen, Meijie (författare)
- Univ Sci & Technol China, Affiliated Hosp 1, Clin Res Hosp,Chinese Acad Sci Hefei, Inst Endocrine & Metab Dis,USTC,Dept Endocrinol,D, Hefei, Anhui, Peoples R China.
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- Xiao, Jianbo (författare)
- Univ Vigo, Dept Analyt Chem & Food Sci, Vigo, Spain.
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- El-Seedi, Hesham R. (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap,Jiangsu Univ, Int Res Ctr Food Nutr & Safety, Zhenjiang, Jiangsu, Peoples R China,Pharmacognosy Group
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- Skalicka Wozniak, Krystyna (författare)
- Med Univ Lublin, Dept Nat Prod Chem, Lublin, Poland.
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- Daglia, Maria (författare)
- Jiangsu Univ, Int Res Ctr Food Nutr & Safety, Zhenjiang, Jiangsu, Peoples R China.;Univ Napoli Federico II, Dept Pharm, Naples, Italy.
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- Little, Peter J. (författare)
- Univ Queensland, Pharm Australia Ctr Excellence, Sch Pharm, Woolloongabba, Qld, Australia.
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- Weng, Jianping (författare)
- Univ Sci & Technol China, Affiliated Hosp 1, Clin Res Hosp,Chinese Acad Sci Hefei, Inst Endocrine & Metab Dis,USTC,Dept Endocrinol,D, Hefei, Anhui, Peoples R China.
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- Xu, Suowen (författare)
- Univ Sci & Technol China, Affiliated Hosp 1, Clin Res Hosp,Chinese Acad Sci Hefei, Inst Endocrine & Metab Dis,USTC,Dept Endocrinol,D, Hefei, Anhui, Peoples R China.
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Univ Sci & Technol China, Affiliated Hosp 1, Clin Res Hosp,Chinese Acad Sci Hefei, Inst Endocrine & Metab Dis,USTC,Dept Endocrinol,D, Hefei, Anhui, Peoples R China Univ Vigo, Dept Analyt Chem & Food Sci, Vigo, Spain. (creator_code:org_t)
- 2022-09-13
- 2024
- Engelska.
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Ingår i: Critical reviews in food science and nutrition. - : Taylor & Francis. - 1040-8398 .- 1549-7852. ; 64:8, s. 2157-2175
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Natural products possess pleiotropic cardiovascular protective effects owing to their anti-oxidation, anti-inflammation and anti-thrombotic properties. Kaempferol, (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), is a kind of naturally occurring flavonoid existing in many common fruits and vegetables (e.g., onions, broccoli, strawberries and grapes) and particularly in traditional Chinese medicine as exemplified by Ginkgo biloba. Epidemiological, preclinical and clinical studies have revealed an inverse association between the consumption of kaempferol-containing foods and medicines and the risk of developing cardiovascular diseases. Numerous translational studies in experimental animal models and cultured cells have demonstrated a wide range of pharmacological activities of kaempferol. In this article, we reviewed the antioxidant, anti-inflammatory and cardio-protective activities of kaempferol and elucidated the potential molecular basis of the therapeutic capacity of kaempferol by focusing on its anti-atherosclerotic effects. Overall, the review presents the health benefits of kaempferol-containing plants and medicines and reflects on the potential of kaempferol as a possible drug candidate to prevent and treat atherosclerosis, the underlying pathology of most cardiovascular diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Kaempferol
- cardiovascular diseases
- medicinal plants
- antioxidant
- anti-inflammatory effects
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