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Conformational stability of adsorbed insulin studied with mass spectrometry and hydrogen exchange

Buijs, J (author)
Uppsala universitet
Vera, CC (author)
Uppsala universitet
Ayala, E (author)
Uppsala universitet
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Steensma, E (author)
Uppsala universitet
Hakansson, P (author)
Uppsala universitet
Oscarsson, S (author)
Uppsala universitet
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 (creator_code:org_t)
AMER CHEMICAL SOC, 1999
1999
English.
In: ANALYTICAL CHEMISTRY. - : AMER CHEMICAL SOC. - 0003-2700. ; 71:15, s. 3219-3225
  • Journal article (other academic/artistic)
Abstract Subject headings
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  • A new method is described for direct monitoring of the conformational stability of proteins that are physically adsorbed from solution onto a solid substrate. The adsorption-induced conformational changes of insulin are studied using a combination of hydr

Keyword

LASER-DESORPTION IONIZATION; SOLID-SURFACES; ADSORPTION-KINETICS; PROTEINS; DESORPTION/IONIZATION; REFLECTOMETRY; SPECTROSCOPY; PROINSULIN; INTERFACES; ASSIGNMENT

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vet (subject category)
art (subject category)

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