Computational prediction of structure, substrate binding mode, mechanism, and rate for a malaria protease with a novel type of active site.

Ämnesord

NATURVETENSKAP  -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)

NATURAL SCIENCES  -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)

Nyckelord

Animals

Aspartic Endopeptidases/antagonists & inhibitors/*chemistry/*metabolism

Binding Sites

Catalysis

Computational Biology/methods

Crystallography; X-Ray

Enzyme Inhibitors/chemistry

Malaria; Falciparum/*enzymology

Models; Chemical

Models; Molecular

Plasmodium falciparum/*enzymology

Predictive Value of Tests

Research Support; Non-U.S. Gov't

Structural Homology; Protein

Substrate Specificity

Thermodynamics

Biochemistry

Publikations- och innehållstyp

vet (ämneskategori)

art (ämneskategori)