Paclitaxel-induced cytotoxicity--the effects of cremophor EL (castor oil) on two human breast cancer cell lines with acquired multidrug resistant phenotype and induced expression of the permeability glycoprotein.

Nyckelord

Breast Neoplasms/chemistry/*drug therapy/genetics/pathology

Carrier Proteins/analysis

Cell Survival/drug effects

Dose-Response Relationship; Drug

Doxorubicin/*pharmacology

Drug Resistance/genetics

Drug Screening Assays; Antitumor

Drug Synergism

Ethanol/pharmacology

Female

Glycerol/*analogs & derivatives/pharmacology

Humans

Membrane Glycoproteins/analysis

Neoplasm Proteins/analysis

P-Glycoprotein

Paclitaxel/*pharmacology

Phenotype

Research Support; Non-U.S. Gov't

Solvents/*pharmacology

Tumor Cells; Cultured

Publikations- och innehållstyp

vet (ämneskategori)

art (ämneskategori)