Cloning and structural analysis of leydin, a novel human serine protease expressed by the Leydig cells of the testis

• We present the cloning and structural analysis of a novel member of the large family of trypsin-related serine proteases. Northern blot analysis shows that this protease, in adult tissues, is expressed almost exclusively in the human testis. In addition,

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serine protease; Leydig cells; human; HMC-1; trypsin; COMPLETE CDNA SEQUENCE; AMINO-ACID-SEQUENCE; MAST-CELL; CHROMOSOMAL ASSIGNMENT; NUCLEOTIDE-SEQUENCE; MOLECULAR-CLONING; MESSENGER-RNA; PROMYELOCYTIC LEUKEMIA; ESCHERICHIA-COLI; DISULFIDE BONDS

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