Cytokines affect PDX-1 expression, insulin and proinsulin secretion from iNOS deficient murine islets.

Nyckelord

Animals

Cytokines/*pharmacology

Glucose/pharmacology

Homeodomain Proteins/*metabolism

Insulin/*secretion

Interferon Type II/pharmacology

Interleukin-1/pharmacology

Islets of Langerhans/*drug effects/secretion

Mice

Mice; Mutant Strains

Nitric Oxide/metabolism

Nitric Oxide Synthase Type II/*deficiency/genetics

Phospholipase D/genetics/metabolism

Proinsulin/*secretion

Proprotein Convertase 1/genetics/metabolism

Proprotein Convertase 2/genetics/metabolism

RNA; Messenger/analysis/metabolism

Research Support; Non-U.S. Gov't

Trans-Activators/*metabolism

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)