Sökning: WFRF:(Gustafsson Ingemar) >
The intra- and inte...
The intra- and inter-day repeatability of corneal densitometry measurements in subjects with keratoconus and in healthy controls
-
- Gustafsson, Ingemar (författare)
- Lund University,Lunds universitet,Klinisk forskning inom hornhinnesjukdomar,Forskargrupper vid Lunds universitet,Clinical research in corneal disease and disorders,Lund University Research Groups,Skåne University Hospital
-
- Bizios, Dimitrios (författare)
- Lund University,Lunds universitet,Oftalmologi (Malmö),Forskargrupper vid Lunds universitet,Ophthalmology (Malmö),Lund University Research Groups
-
- Ivarsen, Anders (författare)
- Aarhus University Hospital
-
visa fler...
-
- Hjortdal, Jesper Ø (författare)
- Aarhus University Hospital
-
visa färre...
-
(creator_code:org_t)
- 2023
- 2023
- Engelska.
-
Ingår i: Scientific Reports. - 2045-2322. ; 13
- Relaterad länk:
-
http://dx.doi.org/10... (free)
-
visa fler...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- The healthy cornea is transparent, however, disease can affect its structure, rendering it more or less opaque. The ability to assess the clarity of the cornea objectively could thus be of considerable interest for keratoconus patients. It has previously been suggested that densitometry can be used to diagnose early keratoconus, and that the values of densitometry variables increase with increasing disease severity, indicating that densitometry could also be used to assess progressive keratoconus. Previous studies have only assessed the repeatability of corneal densitometry measurements on the same day, which does not reflect the clinical setting in which changes are evaluated over time. We have therefore evaluated the inter-day repeatability of densitometry measurements in both patients with keratoconus and healthy controls. Measurements in the middle layer of the 2-6 mm zone of the cornea showed the best repeatability. Although an objective measure of the corneal transparency could be interesting, the generally poor repeatability of densitometry measurements limits their use. The repeatability of corneal clarity measurements could be improved by using other approaches such as optical coherence tomography, but this remains to be investigated. Such improvements would allow the more widespread use of corneal densitometry in clinical practice.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Nyckelord
- Humans
- Keratoconus/diagnosis
- Corneal Topography
- Densitometry/methods
- Cornea
- Visual Acuity
- Reproducibility of Results
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas