Genome-wide identification of quantitative trait loci in a cross between Hampshire and Landrace I: carcass traits

Genome-wide identification of quantitative trait loci in a cross between Hampshire and Landrace I : carcass traits

We report the identification of quantitative trait loci (QTL) affecting carcass composition, carcass length, fat deposition and lean meat content using a genome scan across 462 animals from a combined intercross and backcross between Hampshire and Landrace pigs. Data were analysed using multiple linear regression fitting additive and dominance effects. This model was compared with a model including a parent-of-origin effect to spot evidence of imprinting. Several precisely defined muscle phenotypes were measured in order to dissect body composition in more detail. Three significant QTL were detected in the study at the 1% genome-wide level, and twelve significant QTL were detected at the 5% genome-wide level. These QTL comprise loci affecting fat deposition and lean meat content on SSC1, 4, 9, 10, 13 and 16, a locus on SSC2 affecting the ratio between weight of meat and bone in back and weight of meat and bone in ham and two loci affecting carcass length on SSC12 and 17. The well-defined phenotypes in this study enabled us to detect QTL for sizes of individual muscles and to obtain information of relevance for the description of the complexity underlying other carcass traits.

Bruun, Camilla S. (författare)
von Seth, Gertrud (författare)
Jørgensen, Claus B. (författare)
Andersson, LeifUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi(Swepub:uu)leand227 (författare)
Fredholm, Merete (författare)
Braunschweig, Martin H. (författare)
Sawera, Milena (författare)
Markljung, EllenUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi (författare)
Enfält, Ann-Charlotte (författare)
Hedebro-Velander, Ingela (författare)
Josell, Åsa (författare)
Lindahl, Gunilla (författare)
Lundström, Kerstin (författare)
Uppsala universitetInstitutionen för medicinsk biokemi och mikrobiologi (creator_code:org_t)

Av författaren/redakt...: Karlskov-Mortens ...; Bruun, Camilla S ...; von Seth, Gertru ...; Jørgensen, Claus ...; Andersson, Leif; Fredholm, Merete; visa fler...; Braunschweig, Ma ...; Sawera, Milena; Markljung, Ellen; Enfält, Ann-Char ...; Hedebro-Velander ...; Josell, Åsa; Lindahl, Gunilla; Lundström, Kerst ...; visa färre...

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