A retrospective study on the microbiology in patients with oral complaints and oral mucosal lesions.

• OBJECTIVE: The aim of this study was to microbiologically analyze oral mucosal samples collected during 2 years from patients with oral mucosal complaints. MATERIALS AND METHODS: Mucosal scraping samples were taken from 297 patients and semiquantified by culture for detection of opportunistic microorganisms e.g. Staphylococcus aureus, enterococci, aerobic Gram-negative bacilli (AGNB) and yeasts. Antibiotic susceptibility test was performed. RESULTS: Altogether 297 patients were sampled (mean age 56.8 +/- 20.7). Among the 110 patients with known medical condition, 48 were systemically immunocompromised, 35 had systemic diseases, and 27 had only local oral complaints. Opportunists in moderate growth or more were present commonly in all three groups and most frequent in the immunocompromised patients (66.7%). Candida species were the most frequent opportunist (68.8%), however, their level was low and combinations with bacterial opportunists were common (39.6%). All bacterial opportunists tested were antibiotic multiresistant. Follow-up samples were collected in 23 cases out of which seven showed still presence of opportunists in heavy growth despite repeated treatment with ciprofloxacin. CONCLUSIONS: This study showed a frequent presence of bacterial and fungal opportunists in patients with oral mucosal complaints, which were most common in immunocompromised individuals, however, also frequent in patients with local oral complaints only. Systematic evaluation of different treatment strategies is needed.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Nyckelord

Anti-Bacterial Agents

pharmacology

therapeutic use

Antifungal Agents

pharmacology

therapeutic use

Bacteria

classification

isolation & purification

Candida

classification

isolation & purification

Candidiasis

Oral

microbiology

Disease

Drug Resistance

Bacterial

Enterobacteriaceae

isolation & purification

Enterobacteriaceae Infections

microbiology

Enterococcus

isolation & purification

Female

Gram-Positive Bacterial Infections

microbiology

Humans

Immunocompromised Host

Male

Middle Aged

Mouth

microbiology

Mouth Diseases

drug therapy

microbiology

Mouth Mucosa

microbiology

Opportunistic Infections

microbiology

Organ Transplantation

Pseudomonas Infections

microbiology

Retrospective Studies

Staphylococcal Infections

microbiology

Streptococcal Infections

microbiology

Viridans Streptococci

isolation & purification

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)