Sökning: WFRF:(Bueter Marco) >
Gastric bypass incr...
Gastric bypass increases energy expenditure in rats.
-
Bueter, Marco (författare)
-
Löwenstein, Christian (författare)
-
- Olbers, Torsten, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för gastrokirurgisk forskning och utbildning,Institute of Clinical Sciences, Department of Gastrosurgical Research and Education
-
visa fler...
-
Wang, Maggie (författare)
-
Cluny, Nina L (författare)
-
Bloom, Stephen R (författare)
-
Sharkey, Keith A (författare)
-
Lutz, Thomas A (författare)
-
le Roux, Carel W (författare)
-
visa färre...
-
(creator_code:org_t)
- Elsevier BV, 2010
- 2010
- Engelska.
-
Ingår i: Gastroenterology. - : Elsevier BV. - 1528-0012 .- 0016-5085. ; 138:5, s. 1845-53
- Relaterad länk:
-
https://www.zora.uzh...
-
visa fler...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- BACKGROUND & AIMS: Mechanisms underlying weight loss maintenance after gastric bypass are poorly understood. Our aim was to examine the effects of gastric bypass on energy expenditure in rats. METHODS: Thirty diet-induced obese male Wistar rats underwent either gastric bypass (n = 14), sham-operation ad libitum fed (n = 8), or sham-operation body weight-matched (n = 8). Energy expenditure was measured in an open circuit calorimetry system. RESULTS: Twenty-four-hour energy expenditure was increased after gastric bypass (4.50 +/- 0.04 kcal/kg/h) compared with sham-operated, ad libitum fed (4.29 +/- 0.08 kcal/kg/h) and sham-operated, body weight-matched controls (3.98 +/- 0.10 kcal/kg/h, P < .001). Gastric bypass rats showed higher energy expenditure during the light phase than sham-operated control groups (sham-operated, ad libitum fed: 3.63 +/- 0.04 kcal/kg/h vs sham-operated, body weight-matched: 3.42 +/- 0.05 kcal/kg/h vs bypass: 4.12 +/- 0.03 kcal/kg/h, P < .001). Diet-induced thermogenesis was elevated after gastric bypass compared with sham-operated, body weight-matched controls 3 hours after a test meal (0.41% +/- 1.9% vs 10.5% +/- 2.0%, respectively, P < .05). The small bowel of gastric bypass rats was 72.1% heavier because of hypertrophy compared with sham-operated, ad libitum fed rats (P < .0001). CONCLUSIONS: Gastric bypass in rats prevented the decrease in energy expenditure after weight loss. Diet-induced thermogenesis was higher after gastric bypass compared with body weight-matched controls. Raised energy expenditure may be a mechanism explaining the physiologic basis of weight loss after gastric bypass.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Animals
- Body Composition
- Calorimetry
- Indirect
- Disease Models
- Animal
- Eating
- Energy Metabolism
- Gastric Bypass
- Hypertrophy
- Intestine
- Small
- pathology
- surgery
- Male
- Motor Activity
- Obesity
- metabolism
- physiopathology
- surgery
- Photoperiod
- Pulmonary Gas Exchange
- Rats
- Rats
- Wistar
- Thermogenesis
- Time Factors
- Weight Loss
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Bueter, Marco
-
Löwenstein, Chri ...
-
Olbers, Torsten, ...
-
Wang, Maggie
-
Cluny, Nina L
-
Bloom, Stephen R
-
visa fler...
-
Sharkey, Keith A
-
Lutz, Thomas A
-
le Roux, Carel W
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Kirurgi
- Artiklar i publikationen
-
Gastroenterology
- Av lärosätet
-
Göteborgs universitet