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Preventive effect o...
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Nordström, Anna,1955Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
(författare)
Preventive effect of high-fluoride dentifrice (5,000 ppm) in caries-active adolescents: a 2-year clinical trial.
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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2010-07-03
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S. Karger AG,2010
Nummerbeteckningar
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LIBRIS-ID:oai:gup.ub.gu.se/133280
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https://gup.ub.gu.se/publication/133280URI
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https://doi.org/10.1159/000317490DOI
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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There is a lack of clinical studies comparing dentifrices with high fluoride (F) concentration. The aim was to evaluate a dentifrice containing 5,000 ppm F compared to a dentifrice containing 1,450 ppm F in caries-active adolescents. The design was a 2-year, single-blind randomized controlled trial and 211 adolescents of 279 (76%) completed the trial. The subjects were divided into two groups and were given one of the assigned F dentifrices for daily unsupervised toothbrushing: (1) Duraphat 5,000 ppm F and (2) Pepsodent Superfluor 1,450 ppm F, both as NaF. The outcome variables were caries incidence and progression of proximal and occlusal caries. The subjects were asked to fill in a questionnaire to evaluate their compliance and they were divided into two subgroups: subgroup A, excellent compliance, and subgroup B, poor compliance. The latter group (28%) comprised the subjects who did not brush twice a day or did not use the dentifrice regularly. Adolescents using 5,000 ppm F toothpaste had significantly lower progression of caries compared to those using 1,450 ppm F toothpaste (A: p < 0.01, B: p < 0.001), with a prevented fraction of 40%. Subjects using 5,000 ppm F toothpaste had significantly lower caries incidence for compliance B compared to those using 1,450 ppm F toothpaste (p < 0.05); the prevented fraction was 42%. This may indicate that 5,000 ppm F toothpaste has a greater impact on individuals who do not use toothpaste regularly or do not brush twice a day. Thus, 5,000 ppm F toothpaste appears to be an important vehicle for caries prevention and treatment of adolescents with a high caries risk.
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Birkhed, Dowen,1946Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology(Swepub:gu)xbirdo
(författare)
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Göteborgs universitetInstitutionen för odontologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Caries research: S. Karger AG44:3, s. 323-311421-976X0008-6568
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