Search: id:"swepub:oai:gup.ub.gu.se/138797" >
Influence of Smokin...
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Tettamanti, GiorgioKarolinska Institutet
(author)
Influence of Smoking, Coffee, and Tea Consumption on Bladder Pain Syndrome in Female Twins.
- Article/chapterEnglish2011
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LIBRIS-ID:oai:gup.ub.gu.se/138797
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https://gup.ub.gu.se/publication/138797URI
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https://doi.org/10.1016/j.urology.2010.12.072DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:122670013URI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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OBJECTIVES: To assess the influence of smoking, coffee and tea consumption on the risk for bladder pain syndrome (BPS) using the O'Leary Interstitial Cystitis Symptom Index (ICSI). METHODS: In 2005, all twins born between 1959 and 1985 in Sweden (n = 42,852) were invited to participate in a web-based survey to screen for complex diseases, including BPS. Analyses were limited to female twins with information regarding bladder pain symptoms (n = 9349). Women with an ICSI score ≥6 with required nocturia and bladder pain were defined as having BPS symptoms. Logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (CIs). Environmental and genetic influences were assessed in co-twin control analysis. RESULTS: Tea consumption was associated with an increased risk for BPS (OR 1.26, 95% CI 1.02-1.55 for low tea consumption; OR 1.74, 95% CI 1.24-2.44 for high tea consumption). Coffee consumption was not a risk factor for BPS (OR 1.1, 95% CI .84-1.45). Former and current smoking was associated with a higher risk of BPS (OR 1.5, 95% CI 1.18-1.89; and OR 1.49, 95% CI 1.16-1.92, respectively), but results from co-twin control analysis suggested that the association between smoking and BPS was confounded by familial factors. CONCLUSIONS: Tea and smoking are environmental risk factors for BPS, which are amenable to intervention. The effects of smoking on the risk for BPS may, however, be confounded by familial factors.
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Nyman-Iliadou, Anastasia
(author)
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Pedersen, Nancy LKarolinska Institutet
(author)
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Bellocco, RinoKarolinska Institutet
(author)
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Milsom, Ian,1950Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xmilia
(author)
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Altman, DanielKarolinska Institutet
(author)
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Karolinska InstitutetInstitutionen för kliniska vetenskaper
(creator_code:org_t)
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In:Urology: Elsevier BV1527-99950090-4295
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