Search: WFRF:(Middelveld R. J. M.)
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Assessment of probl...
Assessment of problematic severe asthma in children.
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Lødrup Carlsen, K C (author)
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- Hedlin, G (author)
- Karolinska Institutet
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Bush, A (author)
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- Wennergren, Göran, 1947 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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de Benedictis, F M (author)
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de Jongste, J C (author)
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Baraldi, E (author)
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Pedroletti, C (author)
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Barbato, A (author)
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Malmström, K (author)
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Pohunek, P (author)
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Sindet-Pedersen, Steen (author)
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Piacentini, G L (author)
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- Middelveld, R J M (author)
- Karolinska Institutet
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Carlsen, K H (author)
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(creator_code:org_t)
- 2010-10-28
- 2011
- English.
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In: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 37:2, s. 432-40
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Abstract
Subject headings
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- Assessment of problematic severe asthma in children should be performed in a step-wise manner to ensure an optimal approach. A four-step assessment scheme is proposed. First, a full diagnostic work-up is performed to exclude other diseases which mimic asthma. Secondly, a multi-disciplinary assessment is performed to identify issues that may need attention, including comorbidities. Thirdly, the pattern of inflammation is assessed, and finally steroid responsiveness is documented. Based upon these four steps an optimal individualised treatment plan is developed. In this article the many gaps in our current knowledge in all these steps are highlighted, and recommendations for current clinical practice and future research are made. The lack of good data and the heterogeneity of problematic severe asthma still limit our ability to optimise the management on an individual basis in this small, but challenging group of patients.
Subject headings
- SAMHÄLLSVETENSKAP -- Annan samhällsvetenskap -- Övrig annan samhällsvetenskap (hsv//swe)
- SOCIAL SCIENCES -- Other Social Sciences -- Other Social Sciences not elsewhere specified (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Keyword
- Anti-Asthmatic Agents
- therapeutic use
- Asthma
- diagnosis
- drug therapy
- physiopathology
- Bronchial Hyperreactivity
- diagnosis
- drug therapy
- epidemiology
- Child
- Comorbidity
- Humans
- Respiratory Function Tests
- Rhinitis
- diagnosis
- drug therapy
- epidemiology
- Severity of Illness Index
- Treatment Outcome
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Lødrup Carlsen, ...
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Hedlin, G
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Bush, A
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Wennergren, Göra ...
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de Benedictis, F ...
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de Jongste, J C
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show more...
-
Baraldi, E
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Pedroletti, C
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Barbato, A
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Malmström, K
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Pohunek, P
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Sindet-Pedersen, ...
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Piacentini, G L
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Middelveld, R J ...
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Carlsen, K H
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show less...
- About the subject
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Other Social Sci ...
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and Other Social Sci ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Immunology in th ...
- Articles in the publication
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The European res ...
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European Respira ...
- By the university
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University of Gothenburg
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Karolinska Institutet