id:"swepub:oai:gup.ub.gu.se/144544"
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- Hansson, JohanKarolinska Institutet (author)
Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial.
- Article/chapterEnglish2011
Publisher, publication year, extent ...
- 2011
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/144544
- https://gup.ub.gu.se/publication/144544URI
- https://doi.org/10.1016/S1470-2045(10)70288-6DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:122029343URI
Supplementary language notes
- Language:English
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- SwePubSwePub
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Notes
- Adjuvant high-dose interferon alfa-2b improves relapse-free survival (RFS) in patients with high-risk melanoma, although benefits in overall survival are uncertain. Because of the toxic effects of high-dose regimens, intermediate doses are being explored. We investigated whether adjuvant therapy with intermediate-dose interferon alfa-2b for 1 or 2 years would improve outcomes in patients with stage IIB-IIC or III resected cutaneous melanoma.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
- Adolescent
- Adult
- Aged
- Antineoplastic Agents
- therapeutic use
- Chemotherapy
- Adjuvant
- methods
- Disease-Free Survival
- Dose-Response Relationship
- Drug
- Female
- Humans
- Interferon Alfa-2b
- therapeutic use
- Male
- Melanoma
- drug therapy
- Middle Aged
- Risk Factors
- Time Factors
Added entries (persons, corporate bodies, meetings, titles ...)
- Aamdal, Steinar (author)
- Bastholt, Lars (author)
- Brandberg, YvonneKarolinska Institutet (author)
- Hernberg, Micaela (author)
- Nilsson, Bo (author)
- Stierner, Ulrika,1952Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology(Swepub:gu)xstiul (author)
- von der Maase, Hans (author)
- Karolinska InstitutetInstitutionen för kliniska vetenskaper, Avdelningen för onkologi (creator_code:org_t)
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- In:The lancet oncology12:2, s. 144-521474-5488
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