Sökning: WFRF:(O'Brien Sallyann L) >
Validation of cytop...
Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer.
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Rexhepaj, Elton (författare)
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- Jirström, Karin (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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O'Connor, Darran P (författare)
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O'Brien, Sallyann L (författare)
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- Landberg, Göran, 1963 (författare)
- Lund University,Lunds universitet,Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för patologi,Institute of Biomedicine, Department of Pathology,Patologi, Malmö,Forskargrupper vid Lunds universitet,Pathology, Malmö,Lund University Research Groups
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Duffy, Michael J (författare)
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Brennan, Donal J (författare)
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Gallagher, William M (författare)
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(creator_code:org_t)
- 2010-11-23
- 2010
- Engelska.
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Ingår i: BMC cancer. - : Springer Science and Business Media LLC. - 1471-2407. ; 10
- Relaterad länk:
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https://bmccancer.bi...
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https://portal.resea... (primary) (free)
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http://dx.doi.org/10... (free)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Conflicting data exist regarding the prognostic and predictive impact of survivin (BIRC5) in breast cancer. We previously reported survivin cytoplasmic-to-nuclear ratio (CNR) as an independent prognostic indicator in breast cancer. Here, we validate survivin CNR in a separate and extended cohort. Furthermore, we present new data suggesting that a low CNR may predict outcome in tamoxifen-treated patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Adult
- Aged
- Aged
- 80 and over
- Algorithms
- Breast Neoplasms
- chemistry
- mortality
- therapy
- Cell Nucleus
- chemistry
- Chi-Square Distribution
- Cytoplasm
- chemistry
- Decision Trees
- Estrogen Receptor Modulators
- therapeutic use
- Female
- Humans
- Image Interpretation
- Computer-Assisted
- Immunohistochemistry
- Inhibitor of Apoptosis Proteins
- Kaplan-Meier Estimate
- Ki-67 Antigen
- analysis
- Microtubule-Associated Proteins
- analysis
- Middle Aged
- Pattern Recognition
- Automated
- Predictive Value of Tests
- Proportional Hazards Models
- Receptor
- erbB-2
- analysis
- Receptors
- Estrogen
- analysis
- Receptors
- Progesterone
- analysis
- Reproducibility of Results
- Risk Assessment
- Risk Factors
- Sweden
- Tamoxifen
- therapeutic use
- Time Factors
- Tissue Array Analysis
- Treatment Outcome
- Tumor Markers
- Biological
- analysis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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