Body Mass Index, Cognition, Disability, APOE Genotype, and Mortality: The "Treviso Longeva" Study

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Durante M) > (2010-2014) > Body Mass Index, Co...

Details
MARC

Gustafson, Deborah,1966Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry (author)

Body Mass Index, Cognition, Disability, APOE Genotype, and Mortality: The "Treviso Longeva" Study

Article/chapterEnglish2012

Publisher, publication year, extent ...

2012

Numbers

LIBRIS-ID:oai:gup.ub.gu.se/160940
https://gup.ub.gu.se/publication/160940URI
https://doi.org/10.1097/JGP.0b013e31823031a4DOI

Supplementary language notes

Language:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Objectives: The concurrent contributions of dynamic, interrelated late-life parameters, such as bodymass index (BMI), cognition, and physical functioning on mortality in the elderly are unclear, as is the influence of APOE genotype. We explored these measures in relation to 7-year mortality in long-lived Italian elderly. Design: A representative, age-stratified, population sample. Setting: The Treviso Longeva (TRELONG) Study, in Treviso, Italy. Participants: Three hundred eleven men and 357 women, aged 70 years and older (mean age 84 +/- 8 years). Measurements: Seven-year mortality, BMI, Mini-Mental State Examination (MMSE) score, Activities of Daily Living (ADL), APOE genotype, and a variety of clinical and survey data. Results: In separate age-and sex-adjusted analyses, BMI <18.5 kg/m(2), MMSE <= 24, and ADL <6, were associated with greater 7-year mortality among adults aged 70 years and older. In a multivariate model including all factors, MMSE <= 24, and ADL <6 were associated with greater mortality; BMI >= 30 kg/m(2) was protective. There were no interactions between BMI, MMSE, or ADL. When excluding those dying within 3 years of baseline, only an MMSE <= 24 was related to mortality. APOE epsilon 4 was not related to mortality. Conclusion: Higher MMSE score, higher ADL score, and higher BMI, independent of age, sex, and other factors, are markers for longer life among northern Italian adults aged 70 years or older. Global cognition, BMI, and physical functioning, assessed by short, simple tests are profound indicators of death within less than a decade. (Am J Geriatr Psychiatry 2012; 20:594-602)

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Geriatrik hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Geriatrics hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Psykiatri hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Psychiatry hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
ADL
APOE
BMI
cognition
mortality
alzheimer-disease
longitudinal population
incident dementia
united-states
late-life
aged 70
survival
weight
risk
cholesterol

Added entries (persons, corporate bodies, meetings, titles ...)

Mazzuco, S. (author)
Ongaro, F. (author)
Antuono, P. (author)
Forloni, G. (author)
Albani, D. (author)
Gajo, G. B. (author)
Durante, E. (author)
Caberlotto, L. (author)
Zanardo, A. (author)
Siculi, M. (author)
Gallucci, M. (author)
Göteborgs universitetInstitutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi (creator_code:org_t)

Related titles

In:American Journal of Geriatric Psychiatry20:7, s. 594-6021064-7481

Internet link

Find in a library

American Journal of Geriatric Psychiatry (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Gustafson, Debor ...; Mazzuco, S.; Ongaro, F.; Antuono, P.; Forloni, G.; Albani, D.; show more...; Gajo, G. B.; Durante, E.; Caberlotto, L.; Zanardo, A.; Siculi, M.; Gallucci, M.; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Geriatrics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Neurology

Articles in the publication: American Journal ...

By the university: University of Gothenburg

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se