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Lapatinib with tras...
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial.
- Article/chapterEnglish2012
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LIBRIS-ID:oai:gup.ub.gu.se/163572
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https://gup.ub.gu.se/publication/163572URI
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https://doi.org/10.1016/S0140-6736(11)61847-3DOI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The anti-HER2 monoclonal antibody trastuzumab and the tyrosine kinase inhibitor lapatinib have complementary mechanisms of action and synergistic antitumour activity in models of HER2-overexpressing breast cancer. We argue that the two anti-HER2 agents given together would be better than single-agent therapy.
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Bradbury, Ian
(author)
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Eidtmann, Holger
(author)
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Di Cosimo, Serena
(author)
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de Azambuja, Evandro
(author)
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Aura, Claudia
(author)
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Gómez, Henry
(author)
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Dinh, Phuong
(author)
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Fauria, Karine
(author)
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Van Dooren, Veerle
(author)
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Aktan, Gursel
(author)
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Goldhirsch, Aron
(author)
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Chang, Tsai-Wang
(author)
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Horváth, Zsolt
(author)
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Coccia-Portugal, Maria
(author)
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Domont, Julien
(author)
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Tseng, Ling-Min
(author)
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Kunz, Georg
(author)
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Sohn, Joo Hyuk
(author)
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Semiglazov, Vladimir
(author)
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Lerzo, Guillermo
(author)
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Palacova, Marketa
(author)
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Probachai, Volodymyr
(author)
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Pusztai, Lajos
(author)
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Untch, Michael
(author)
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Gelber, Richard D
(author)
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Piccart-Gebhart, Martine
(author)
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Holmberg, Stig B,1946Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
(author)
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Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för kirurgi
(creator_code:org_t)
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In:Lancet379:9816, s. 633-401474-547X
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Baselga, José
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Bradbury, Ian
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Eidtmann, Holger
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Di Cosimo, Seren ...
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de Azambuja, Eva ...
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Aura, Claudia
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Gómez, Henry
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Dinh, Phuong
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Fauria, Karine
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Van Dooren, Veer ...
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Aktan, Gursel
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Goldhirsch, Aron
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Chang, Tsai-Wang
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Horváth, Zsolt
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Coccia-Portugal, ...
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Domont, Julien
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Tseng, Ling-Min
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Kunz, Georg
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Sohn, Joo Hyuk
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Semiglazov, Vlad ...
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Lerzo, Guillermo
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Palacova, Market ...
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Probachai, Volod ...
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Pusztai, Lajos
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Untch, Michael
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Gelber, Richard ...
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Piccart-Gebhart, ...
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Holmberg, Stig B ...
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- MEDICAL AND HEALTH SCIENCES
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and Surgery
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University of Gothenburg