WFRF:(Götlind Yu Yuan)
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- Götlind, Yu-Yuan Chiu,1964Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi,Institute of Biomedicine, Department of Microbiology and Immunology (author)
CD4+FoxP3+ regulatory T cells from Gαi2-/- mice are functionally active in vitro, but do not prevent colitis.
- Article/chapterEnglish2011
Publisher, publication year, extent ...
- 2011-09-22
- Public Library of Science (PLoS),2011
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/173354
- https://gup.ub.gu.se/publication/173354URI
- https://doi.org/10.1371/journal.pone.0025073DOI
Supplementary language notes
- Language:English
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- SwePubSwePub
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Notes
- Mice deficient in the inhibitory G protein subunit Gαi2 spontaneously develop a T helper 1 dominated colitis. We examined whether a defect in CD4(+)FoxP3(+) regulatory T cells (Treg) underpins the pathogenesis of colitis in the Gαi2(-/-) (Gαi2-deficient) colitis model.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Immunologi inom det medicinska området hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Immunology in the medical area hsv//eng
- regulatory T cells
- inflammatory bowel disease
- mouse model
Added entries (persons, corporate bodies, meetings, titles ...)
- Raghavan, Sukanya,1974Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi,Institute of Biomedicine, Department of Microbiology and Immunology(Swepub:gu)xragsu (author)
- Bland, Paul William,1949Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi,Institute of Biomedicine, Department of Microbiology and Immunology(Swepub:gu)xblapa (author)
- Hörnquist, Elisabeth Hultgren (author)
- Göteborgs universitetInstitutionen för biomedicin, avdelningen för mikrobiologi och immunologi (creator_code:org_t)
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- In:PloS one: Public Library of Science (PLoS)6:91932-6203
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