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  • van Krieken, J. H. (author)

Guideline on the requirements of external quality assessment programs in molecular pathology

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • 2012-12-19
  • Springer Science and Business Media LLC,2013

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/174574
  • https://gup.ub.gu.se/publication/174574URI
  • https://doi.org/10.1007/s00428-012-1354-4DOI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Molecular pathology is an integral part of daily diagnostic pathology and used for classification of tumors, for prediction of prognosis and response to therapy, and to support treatment decisions. For these reasons, analyses in molecular pathology must be highly reliable and hence external quality assessment (EQA) programs are called for. Several EQA programs exist to which laboratories can subscribe, but they vary in scope, number of subscribers, and execution. The guideline presented in this paper has been developed with the purpose to harmonize EQA in molecular pathology. It presents recommendations on how an EQA program should be organized, provides criteria for a reference laboratory, proposes requirements for EQA test samples, and defines the number of samples needed for an EQA program. Furthermore, a system for scoring of the results is proposed as well as measures to be taken for poorly performing laboratories. Proposals are made regarding the content requirements of an EQA report and how its results should be communicated. Finally, the need for an EQA database and a participant manual are elaborated. It is the intention of this guideline to improve EQA for molecular pathology in order to provide more reliable molecular analyses as well as optimal information regarding patient selection for treatment.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Normanno, N. (author)
  • Blackhall, F. (author)
  • Boone, E. (author)
  • Botti, G. (author)
  • Carneiro, F. (author)
  • Celik, I. (author)
  • Ciardiello, F. (author)
  • Cree, I. A. (author)
  • Deans, Z. C. (author)
  • Edsjö, AndersGothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center (author)
  • Groenen, Pjta (author)
  • Kamarainen, O. (author)
  • Kreipe, H. H. (author)
  • Ligtenberg, M. J. L. (author)
  • Marchetti, A. (author)
  • Murray, S. (author)
  • Opdam, F. J. M. (author)
  • Patterson, S. D. (author)
  • Patton, S. (author)
  • Pinto, C. (author)
  • Rouleau, E. (author)
  • Schuuring, E. (author)
  • Sterck, S. (author)
  • Taron, M. (author)
  • Tejpar, S. (author)
  • Timens, W. (author)
  • Thunnissen, E. (author)
  • van de Ven, P. M. (author)
  • Siebers, A. G. (author)
  • Dequeker, E. (author)
  • Göteborgs universitetSahlgrenska Cancer Center (creator_code:org_t)

Related titles

  • In:Virchows Archiv: Springer Science and Business Media LLC462:1, s. 27-370945-63171432-2307

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